J. Goverman, Autoimmune T cell responses in the central nervous system, Nat Rev Immunol, vol.9, pp.393-407, 2009.

M. Sospedra and R. Martin, Immunology of multiple sclerosis, Annu Rev Immunol, vol.23, pp.683-747, 2005.

R. Hohlfeld and H. Wekerle, Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: from pipe dreams to (therapeutic) pipelines, Proc Natl Acad Sci, vol.101, issue.2, pp.14599-14606, 2004.

S. L. Hauser, A. K. Bhan, F. Gilles, M. Kemp, C. Kerr et al., Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions, Ann Neurol, vol.19, pp.578-587, 1986.

H. Babbe, A. Roers, and A. Waisman, Clonal expansions of CD8(1) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction, J Exp Med, vol.192, pp.393-404, 2000.

C. Skulina, S. Schmidt, and K. Dornmair, Multiple sclerosis: brain-infiltrating CD81 T cells persist as clonal expansions in the cerebrospinal fluid and blood, Proc Natl Acad Sci, vol.101, pp.2428-2433, 2004.

A. Junker, J. Ivanidze, and J. Malotka, Multiple sclerosis: T-cell receptor expression in distinct brain regions, Brain, vol.130, pp.2789-2799, 2007.

M. A. Friese and L. Fugger, Pathogenic CD8(1) T cells in multiple sclerosis, Ann Neurol, vol.66, pp.132-141, 2009.

A. Saxena, G. Martin-blondel, L. T. Mars, and R. S. Liblau, Role of CD8 T cell subsets in the pathogenesis of multiple sclerosis, FEBS Lett, vol.585, pp.3758-3763, 2011.

M. Montes, X. Zhang, and L. Berthelot, Oligoclonal myelinreactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells, Clin Immunol, vol.130, pp.133-144, 2009.

S. Seitz, C. K. Schneider, and J. Malotka, Reconstitution of paired T cell receptor alpha-and beta-chains from microdissected single cells of human inflammatory tissues, Proc Natl Acad Sci, vol.103, pp.12057-12062, 2006.

F. Tilloy, E. Treiner, and S. H. Park, An invariant T cell receptor alpha chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted alpha/beta T cell subpopulation in mammals, J Exp Med, vol.189, pp.1907-1921, 1999.

E. Martin, E. Treiner, and L. Duban, Stepwise development of MAIT cells in mouse and human, PLoS Biol, vol.7, p.54, 2009.
URL : https://hal.archives-ouvertes.fr/inserm-00707793

M. C. Gold, S. Cerri, and S. Smyk-pearson, Human mucosal associated invariant T cells detect bacterially infected cells, PLoS Biol, vol.8, p.1000407, 2010.
URL : https://hal.archives-ouvertes.fr/inserm-00707307

R. Reantragoon, A. J. Corbett, and I. G. Sakala, Antigenloaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells, J Exp Med, vol.210, pp.2305-2320, 2013.

M. Lepore, A. Kalinichenko, and A. Colone, Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRb repertoire, Nat Commun, vol.5, p.3866, 2014.

E. Treiner, L. Duban, and S. Bahram, Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1, Nature, vol.422, pp.164-169, 2003.

L. Bourhis, L. , M. E. Peguillet, and I. , Antimicrobial activity of mucosal-associated invariant T cells, Nat Immunol, vol.11, pp.701-708, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00550333

M. C. Gold, J. E. Mclaren, and J. A. Reistetter, MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage, J Exp Med, vol.211, pp.1601-1610, 2014.

B. Arden, S. P. Clark, D. Kabelitz, and T. W. Mak, Human T-cell receptor variable gene segment families, Immunogenetics, vol.42, pp.455-500, 1995.

S. M. Kim, L. Bhonsle, and P. Besgen, Analysis of the paired TCR a-and b-chains of single human T cells, PloS One, vol.7, p.37338, 2012.

E. Alamyar, V. Giudicelli, S. Li, P. Duroux, and M. P. Lefranc, IMGT/HighV-QUEST: the IMGT(R) web portal for immunoglobulin (IG) or antibody and T cell receptor (TR) analysis from NGS high throughput and deep sequencing, Immunome Res, vol.8, p.26, 2012.

J. R. Fergusson, V. M. Fleming, and P. Klenerman, CD161-expressing human T cells, Front Immunol, vol.2, p.36, 2011.

Z. Illés, M. Shimamura, J. Newcombe, N. Oka, and T. Yamamura, Accumulation of Valpha7.2-Jalpha33 invariant T cells in human autoimmune inflammatory lesions in the nervous system, Int Immunol, vol.16, pp.223-230, 2004.

V. Annibali, G. Ristori, and D. F. Angelini, CD161(high) CD81T cells bear pathogenetic potential in multiple sclerosis, Brain, vol.134, pp.542-554, 2011.

Y. Miyazaki, S. Miyake, A. Chiba, O. Lantz, and T. Yamamura, Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis, Int Immunol, vol.23, pp.529-535, 2011.

S. V. Abrahamsson, D. F. Angelini, and A. N. Dubinsky, Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis, Brain, vol.136, pp.2888-2903, 2013.

A. Willing, O. A. Leach, and F. Ufer, CD8(1) MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis, Eur J Immunol, vol.44, pp.3119-3128, 2014.

M. Dusseaux, E. Martin, and N. Serriari, Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells, Blood, vol.117, pp.1250-1259, 2011.

H. Wekerle, K. Berer, and G. Krishnamoorthy, Remote controltriggering of brain autoimmune disease in the gut, Curr Opin Immunol, vol.25, pp.683-689, 2013.

L. Kjer-nielsen, O. Patel, and A. J. Corbett, MR1 presents microbial vitamin B metabolites to MAIT cells, Nature, vol.491, pp.717-723, 2012.

O. Patel, L. Kjer-nielsen, L. Nours, and J. , Recognition of vitamin B metabolites by mucosal-associated invariant T cells, Nat Commun, vol.4, p.2142, 2013.