Immune regulatory function of B cells, Annu. Rev. Immunol, vol.30, pp.221-241, 2012. ,
Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice, J. Clin. Invest, vol.121, pp.3645-3656, 2011. ,
Anti-CD45RB/anti-TIM-1-induced tolerance requires regulatory B cells, Am. J. Transplant, vol.12, pp.2072-2078, 2012. ,
TGF-b-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance, Eur. J. Immunol, vol.44, pp.1728-1736, 2014. ,
B-cell-depleting induction therapy and acute cellular rejection, N. Engl. J. Med, vol.360, pp.2683-2685, 2009. ,
Novel suppressive function of transitional 2 B cells in experimental arthritis, J. Immunol, vol.178, pp.7868-7878, 2007. ,
The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals, J. Immunol, vol.182, pp.7459-7472, 2009. ,
Interleukin-35 induces regulatory B cells that suppress autoimmune disease, Nat. Med, vol.20, pp.633-641, 2014. ,
From the regulatory functions of B cells to the identification of cytokine-producing plasma cell subsets, Curr. Opin. Immunol, vol.28, pp.77-83, 2014. ,
CD19+CD24 hi CD38 hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients, Immunity, vol.32, pp.129-140, 2010. ,
Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells, Blood, vol.117, pp.530-541, 2011. ,
Human regulatory B cells combine phenotypic and genetic hallmarks with a distinct differentiation fate, J. Immunol, vol.193, pp.2258-2266, 2014. ,
Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD, Blood, vol.124, pp.2034-2045, 2014. ,
Induction of donor-specific allograft tolerance by short-term treatment with LF15-0195 after transplantation. Evidence for a direct effect on T-cell differentiation, Am. J. Transplant, vol.2, pp.745-757, 2002. ,
Role for thymic and splenic regulatory CD4, 2002. ,
, + T cells induced by donor dendritic cells in allograft tolerance by LF15-0195 treatment, J. Immunol, vol.168, pp.5058-5069
Long-term allograft tolerance is characterized by the accumulation of B cells exhibiting an inhibited profile, Am. J. Transplant, vol.11, pp.429-438, 2011. ,
Patients with drug-free longterm graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype, Kidney Int, vol.78, pp.503-513, 2010. ,
Identification of a B cell signature associated with renal transplant tolerance in humans, J. Clin. Invest, vol.120, pp.1836-1847, 2010. ,
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans, J. Clin. Invest, vol.120, pp.1848-1861, 2010. ,
Unique B cell differentiation profile in tolerant kidney transplant patients, Am. J. Transplant, vol.14, pp.144-155, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-00974748
Improved technique of heart transplantation in rats, J. Thorac. Cardiovasc. Surg, vol.57, pp.225-229, 1969. ,
Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance, J. Immunol, vol.170, pp.1304-1312, 2003. ,
LF 15-0195, a novel immunosuppressive agent prevents rejection and induces operational tolerance in a mouse cardiac allograft model, Transplantation, vol.76, pp.644-650, 2003. ,
Monotherapy with LF 15-0195, an analogue of 15-deoxyspergualin, significantly prolongs renal allograft survival in monkeys, Transplantation, vol.75, pp.1166-1171, 2003. ,
Genetics of the blood transfusion effect on heart allografts in rats, Transplantation, vol.38, pp.63-67, 1984. ,
New evidence for a role of allograft accommodation in long-term tolerance, Transplantation, vol.82, pp.1185-1193, 2006. ,
New lines of GFP transgenic rats relevant for regenerative medicine and gene therapy, Transgenic Res, vol.19, pp.745-763, 2010. ,
Characterization of immunoglobulin heavy chain knockout rats, Eur. J. Immunol, vol.40, pp.2932-2941, 2010. ,
Analysis of relative gene expression data using real-time quantitative PCR and the 2(2DDC T ) method, Methods, vol.25, pp.402-408, 2001. ,
Indirect CD4 + TH1 response, antidonor antibodies and diffuse C4d graft deposits in long-term recipients conditioned by donor antigens priming, Am. J. Transplant, vol.9, pp.697-708, 2009. ,
, MHC-derived allopeptide activates TCR-biased CD8, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-02167782
, + Tregs and suppresses organ rejection, J. Clin. Invest, vol.124, pp.2497-2512
Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice, PLoS One, vol.5, p.15007, 2010. ,
Transcription factor IRF4 regulates germinal center cell formation through a B cellintrinsic mechanism, J. Immunol, vol.192, pp.3200-3206, 2014. ,
Role of IFNg in allograft tolerance mediated by CD4 + CD25 + regulatory T cells by induction of IDO in endothelial cells, Am. J. Transplant, vol.7, pp.2472-2482, 2007. ,
Activated mouse B cells lack expression of granzyme B, J. Immunol, vol.188, pp.3886-3892, 2012. ,
Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions, Nature, vol.491, pp.264-268, 2012. ,
Cutting edge: IL-10-producing regulatory B cells in early human pregnancy, Am. J. Reprod. Immunol, vol.70, pp.448-453, 2013. ,
IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases, Nature, vol.507, pp.366-370, 2014. ,
B-type suppression: a role played by "regulatory B cells" or "regulatory plasma cells"?, Eur. J. Immunol, vol.44, pp.1251-1257, 2014. ,
Deoxyspergualin inhibits kappa light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation, J. Immunol, vol.155, pp.2427-2436, 1995. ,
Murine gammaherpesvirus M2 protein induction of IRF4 via the NFAT pathway leads to IL-10 expression in B cells, PLoS Pathog, vol.10, p.1003858, 2014. ,
Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation, Immunity, vol.41, pp.1040-1051, 2014. ,
Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice, J. Immunol, vol.182, pp.3492-3502, 2009. ,
BANK negatively regulates Akt activation and subsequent B cell responses, Immunity, vol.24, pp.259-268, 2006. ,
Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway, OncoImmunology, vol.1, pp.1368-1375, 2012. ,
Human plasma cells express granzyme B, Eur. J. Immunol, vol.44, pp.275-284, 2014. ,
Trafficking phenotype and production of granzyme B by double negative B cells (IgG + IgD 2 CD27 2 ) in the elderly, Exp. Gerontol, vol.54, pp.123-129, 2014. ,
Interleukin 21-induced granzyme B-expressing B cells infiltrate tumors and regulate T cells, Cancer Res, vol.73, pp.2468-2479, 2013. ,
, , p.5, 2010.
, + B cells from individuals with systemic lupus erythematosus express granzyme B, Eur. J. Immunol, vol.40, pp.2060-2069
Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help, Immunol. Cell Biol, vol.90, pp.457-467, 2012. ,
, , p.4, 2015.
, + T cellderived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients, J. Immunol, vol.194, pp.3768-3777
Tolerant kidney transplant patients produce B cells with regulatory properties, J. Am. Soc. Nephrol, 2015. ,
URL : https://hal.archives-ouvertes.fr/inserm-02148982
CD24 hi CD27 + and plasmablast-like regulatory B cells in human chronic graft-versus-host disease, Blood, vol.125, pp.1830-1839, 2015. ,
Restricted specificity of peripheral alloreactive memory B cells in HLA-sensitized patients awaiting a kidney transplant, Kidney Int, vol.87, pp.1230-1240, 2015. ,
Efficient generation of human alloantigen-specific CD4 + regulatory T cells from naive precursors by CD40-activated B cells, Blood, vol.112, pp.2554-2562, 2008. ,
CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4 + regulatory T cells, Cell. Mol. Immunol, vol.7, pp.44-50, 2010. ,