Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma, J Biol Chem, vol.270, pp.25715-25721, 1995. ,
Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17, Genomics, vol.28, pp.367-376, 1995. ,
TRAF4 overexpression is a common characteristic of human carcinomas, Oncogene, vol.26, pp.142-147, 2007. ,
Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression, Proc Natl Acad Sci, vol.101, pp.9309-9314, 2004. ,
Tumor necrosis factor receptor-associated factors (TRAFs), Oncogene, vol.20, pp.6482-6491, 2001. ,
The seventh ring: exploring TRAF7 functions, J Cell Physiol, vol.227, pp.1280-1284, 2012. ,
TRAF4, the unique family member, Adv Exp Med Biol, vol.597, pp.60-71, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00189185
Phylogeny of the TRAF/ MATH domain, Adv Exp Med Biol, vol.597, pp.1-24, 2007. ,
Dynamic expression of Drosophila TRAF1 during embryogenesis and larval development, Mechanisms of Development, vol.100, pp.506-508, 2001. ,
Complete structural characterisation of the mammalian and Drosophila TRAF genes: implications for TRAF evolution and the role of RING finger splice variants, Mol Immunol, vol.37, pp.721-734, 2000. ,
Discrete functions of TRAF1 and TRAF2 in Drosophila melanogaster mediated by c-Jun Nterminal kinase and NF-kappaB-dependent signaling pathways, Mol Cell Biol, vol.23, pp.7982-7991, 2003. ,
Role for Traf4 in polarizing adherens junctions as a prerequisite for efficient cell shape changes, Mol Cell Biol, vol.31, pp.4978-4993, 2011. ,
Impaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice, Proc Natl Acad Sci, vol.99, pp.5585-5590, 2002. ,
TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs, Am J Pathol, vol.157, issue.10, pp.64578-64584, 2000. ,
In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis, PLoS One, vol.7, p.30917, 2012. ,
Intracellular localization and transcriptional regulation of tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4), Eur J Biochem, vol.269, pp.4819-4829, 2002. ,
Tumor necrosis factor receptor-associated factor 4 is a dynamic tight junction-related shuttle protein involved in epithelium homeostasis, PLoS One, vol.3, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00350795
TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues, Am J Pathol, vol.152, pp.1549-1561, 1998. ,
Tumor necrosis factor receptor-associated factor 4 is a dynamic tight junction-related shuttle protein involved in epithelium homeostasis, PLoS One, vol.3, 2008. ,
SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization, Genes Dev, vol.27, pp.274-287, 2013. ,
Drosophila homologs of mammalian TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in neuroblasts, EMBO J, vol.25, pp.5783-5793, 2006. ,
Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: role of p47phox phosphorylation and binding to TRAF4, Mol Cell Biol, vol.25, pp.2320-2330, 2005. ,
Subcellular targeting of oxidants during endothelial cell migration, J Cell Biol, vol.171, pp.893-904, 2005. ,
TRAF4, at the crossroad between morphogenesis and cancer, Cancers, vol.3, pp.2734-2749, 2011. ,
Tumor necrosis factorreceptor-associated factor-4 is a positive regulator of transforming growth factor-b signaling that affects neural crest formation, Mol Biol Cell, vol.20, pp.3436-3450, 2009. ,
Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development, Mech Dev, vol.71, pp.187-191, 1998. ,
Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane, Development, vol.105, pp.223-235, 1989. ,
Polarity proteins as regulators of cell junction complexes: Implications for breast cancer, Pharmacology & Therapeutics. Available, 2013. ,
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini, Cell, vol.111, pp.29-40, 2002. ,
Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10, Cancer Res, vol.50, pp.6075-6086, 1990. ,
Induction by transforming growth factor-b1 of epithelial to mesenchymal transition is a rare event in vitro, Breast Cancer Res, vol.6, pp.1-17, 2004. ,
Regulation of CXCL8/IL-8 expression by zonula occludens-1 in human breast cancer cells, Mol Cancer Res, vol.10, pp.121-132, 2012. ,
Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex, Mol Biol Cell, vol.16, pp.2636-2650, 2005. ,
Epithelial membrane polarity: a stable, differentiated feature of an established human breast carcinoma cell line MCF-7, J Histochem Cytochem, vol.35, pp.461-469, 1987. ,
The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain, Cell Mol Life Sci, vol.66, pp.3951-3966, 2009. ,
PDZ domains of Par-3 as potential phosphoinositide signaling integrators, Mol Cell, vol.28, pp.886-898, 2007. ,
Protein lipid overlay assay, Science's STKE, pp.6-6, 2002. ,
The tandem affinity purification (TAP) method: a general procedure of protein complex purification, Methods, vol.24, pp.218-229, 2001. ,
Ligand-metal ion binding to proteins: investigation by ESI mass spectrometry, Methods in enzymology, vol.402, pp.361-389, 2005. ,
Structural basis for selfassociation and receptor recognition of human TRAF2, Nature, vol.398, pp.533-538, 1999. ,
, Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation, vol.38, pp.101-113, 2010.
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif, The EMBO J, vol.24, pp.2244-2253, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00090227
Studying in vitro membrane curvature recognition by proteins and its role in vesicular trafficking, Methods Cell Biol, vol.108, pp.47-71, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00759930
Thermodynamic characterization of the interaction between TRAF2 and tumor necrosis factor receptor peptides by isothermal titration calorimetry, PNAS, vol.97, pp.8961-8966, 2000. ,
Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin, EMBO J, vol.24, pp.3985-3995, 2005. ,
Genomewide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains, Molecular Cell, vol.13, pp.677-688, 2004. ,
Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5, Sci Signal, vol.5, p.81, 2012. ,
Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily, vol.68, pp.225-279, 2004. ,
Phosphoinositides in cell architecture, Cold Spring Harb Perspect Biol, vol.3, p.4796, 2011. ,
Molecular characteristics of phosphoinositide binding, Pflugers Arch -Eur J Physiol, vol.455, pp.45-53, 2007. ,
Expression, purification and characterization of fourth FAS1 domain of TGFbIp-associated corneal dystrophic mutants, Protein Expression and Purification, vol.84, pp.108-115, 2012. ,
Development and validation of a genetic algorithm for flexible docking, J Mol Biol, vol.267, pp.727-748, 1997. ,
Phosphoinositides in cell regulation and membrane dynamics, Nature, vol.443, pp.651-657, 2006. ,
Visualisation of cellular phosphoinositide pools with GFP-fused protein-domains, Curr Protoc Cell Biol CHAPTER, 2009. ,
Live cell imaging of phosphoinositide dynamics with fluorescent protein domains, Biochimica et Biophysica Acta (BBA) -Molecular and Cell Biology of Lipids, vol.1761, pp.957-967, 2006. ,
Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells, Nat Cell Biol, vol.8, pp.963-970, 2006. ,
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42, Cell, vol.128, pp.383-397, 2007. ,
Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle, Science, vol.297, pp.1193-1196, 2002. ,
The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes, Biochemistry, vol.34, pp.16228-16234, 1995. ,
Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration, EMBO J, vol.30, pp.665-678, 2011. ,
The epithelial polarity program: machineries involved and their hijacking by cancer, Oncogene, vol.27, pp.6939-6957, 2008. ,
Phosphoinositide signaling pathways: promising role as builders of epithelial cell polarity, Int Rev Cell Mol Biol, vol.273, pp.313-343, 2009. ,
Translation of the phosphoinositide code by PI effectors, Nat Chem Biol, vol.6, pp.507-513, 2010. ,
Pleckstrin homology domain 1 of mouse alpha 1-syntrophin binds phosphatidylinositol 4,5-bisphosphate, Biochemistry, vol.38, pp.5596-5602, 1999. ,
Molecular basis for CD40 signaling mediated by TRAF3, PNAS, vol.97, pp.10395-10399, 2000. ,
Distinct molecular mechanism for initiating TRAF6 signalling, Nature, vol.418, pp.443-447, 2002. ,
TRAF-mediated regulation of immune and inflammatory responses, Sci China Life Sci, vol.53, pp.159-168, 2010. ,
Modular peptide recognition domains in eukaryotic signaling, Annual Review of Biophysics and Biomolecular Structure, vol.26, pp.259-288, 1997. ,
Apicobasal polarity and neural tube closure, Dev Growth Differ, vol.55, pp.164-172, 2013. ,
Tumor necrosis factorreceptor-associated factor-4 is a positive regulator of transforming growth factor-beta signaling that affects neural crest formation, Mol Biol Cell, vol.20, pp.3436-3450, 2009. ,
Interactions between Twist and other core epithelial-mesenchymal transition factors are controlled by GSK3-mediated phosphorylation, Nat Commun, vol.4, p.1542, 2013. ,
The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression, Cell Adh Migr, vol.6, pp.365-373, 2012. ,
Two distinct amplified regions at 17q11-q21 involved in human primary breast cancer, Cancer Res, vol.56, pp.3886-3890, 1996. ,
TRAF4 promotes TGF-b receptor signaling and drives breast cancer metastasis, Mol Cell, 2013. ,
Ubiquitination of tumor necrosis factor receptor-associated factor 4 (TRAF4) by Smad ubiquitination regulatory factor 1 (Smurf1) regulates motility of breast epithelial and cancer cells, J Biol Chem, vol.288, pp.21784-21792, 2013. ,
Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module, J Biol Chem, vol.279, pp.33702-33715, 2004. ,
Tumor necrosis factor receptor-associated factor 4 is a dynamic tight junction-related shuttle protein involved in epithelium homeostasis, PLoS One, vol.3, 2008. ,
Sensitivity of CFP/YFP and GFP/mCherry pairs to donor photobleaching on FRET determination by fluorescence lifetime imaging microscopy in living cells, Microsc Res Tech, vol.69, pp.933-939, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00115169
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen, Cell, vol.124, pp.1283-1298, 2006. ,
The steroidogenic acute regulatory protein homolog MLN64, a late endosomal cholesterol-binding protein, J Biol Chem, vol.276, pp.4261-4269, 2001. ,
, Protein Lipid Overlay Assay. Sci STKE, p.6, 2002.
PCDDB: the Protein Circular Dichroism Data Bank, a repository for circular dichroism spectral and metadata, Nucleic Acids Res, vol.39, pp.480-486, 2011. ,
, XDS. Acta Crystallogr D Biol Crystallogr, vol.66, pp.125-132, 2010.
Scaling and assessment of data quality, Acta Crystallogr D Biol Crystallogr, vol.62, pp.72-82, 2006. ,
An introduction to data reduction: space-group determination, scaling and intensity statistics, Acta Crystallogr D Biol Crystallogr, vol.67, pp.282-292, 2011. ,
, The CCP4 suite: programs for protein crystallography, Acta Crystallogr D Biol Crystallogr, vol.50, pp.760-763, 1994.
Phaser crystallographic software, J Appl Crystallogr, vol.40, pp.658-674, 2007. ,
PHENIX: a comprehensive Python-based system for macromolecular structure solution, Acta Crystallogr D Biol Crystallogr, vol.66, pp.213-221, 2010. ,
CHAINSAW: a program for mutating pdb files used as templates in molecular replacement, Journal of Applied Crystallography, vol.41, pp.641-643, 2008. ,
Solvent content of protein crystals, J Mol Biol, vol.33, pp.491-497, 1968. ,
Features and development of Coot, Acta Crystallogr D Biol Crystallogr, vol.66, pp.486-501, 2010. ,
MolProbity: all-atom structure validation for macromolecular crystallography, Acta Crystallogr D Biol Crystallogr, vol.66, pp.12-21, 2010. ,
PRO-CHECK: a program to check the stereochemical quality of protein structures, J Appl Crystal, vol.26, pp.283-291, 1993. ,
The PyMOL molecular graphics system, 2002. ,
Comparison of automatic threedimensional model builders using 639 X-ray structures, J Chem Inf Comput Sci, vol.34, pp.1000-1008, 1994. ,
, Santa Fe: OpenEye Scientific Software. Available
1699 South Hanley Rd ,
, GOLD (n.d.). Cambridge CB2 1EZ
Automatic atom type and bond type perception in molecular mechanical calculations, J Mol Graph Model, vol.25, pp.247-260, 2006. ,
The Amber biomolecular simulation programs, J Comput Chem, vol.26, pp.1668-1688, 2005. ,
Assembly of epithelial tight junctions is negatively regulated by Par6, Curr Biol, vol.12, pp.663-670, 2002. ,
A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide, J Cell Biol, vol.102, pp.457-468, 1986. ,