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Acquisition duration in resting-state arterial spin labeling. How long is enough?

Corentin Vallée 1, * Pierre Maurel 1 Isabelle Corouge 1 Christian Barillot 1
* Corresponding author
1 Empenn
INSERM - Institut National de la Santé et de la Recherche Médicale, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
Abstract : Resting-state Arterial Spin Labeling (rs-ASL) is a rather confidential method compared to resting-state BOLD but drives great prospects with respect to potential clinical applications. By enabling the study of CBF maps, rs-ASL can lead to significant clinical subject-scaled applications as CBF is a biomarker in neuropathology. An important parameter to consider in functional imaging is the acquisition duration. Despite directly impacting practicability and functional networks representation, there is no standard for rs-ASL. Our work here focuses on strengthening the confidence in ASL as a rs-fMRI method and on studying the influence of the acquisition duration. To this end, we acquired a long rs-ASL sequence and assessed the quality of typical functional brain networks quality over time compared to gold-standard networks. Our results show that after 14 min of duration acquisition, functional networks representation can be considered as stable.
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Submitted on : Wednesday, September 18, 2019 - 5:48:11 PM
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Corentin Vallée, Pierre Maurel, Isabelle Corouge, Christian Barillot. Acquisition duration in resting-state arterial spin labeling. How long is enough?. Frontiers in Neuroscience, Frontiers, 2020, ⟨10.3389/fnins.2020.00598⟩. ⟨inserm-02129799v2⟩

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