HIV infection and care pathway: From guidelines to clinical practice

Abstract : OBJECTIVES: To quantify within a cohort of HIV-infected individuals the number of medical visits and procedures to be carried out according to comorbidities and risk factors to implement a personalized care pathway. PATIENTS AND METHODS: Retrospective study of 915 patients consulting from January 1 to December 31, 2016 at an outpatient unit of multidisciplinary consultations, using an electronic patient record. We built an algorithm using parameters required for the application of the national guidelines for the management of HIV-infected individuals. The frequency of comorbidities was measured according to gender, transmission risk group, and nadir CD4 (200/mm3). RESULTS: Patients were mostly men (median age: 52 years), of whom 16% were aged≥60 years. Viral load was<40 copies/mL in 93.5% of treated patients and CD4 cell count≥500/mm3 for 73%. Overall, 74.5% of patients had at least one comorbidity. The number of comorbidities was similar in men and women but was significantly higher in patients with a nadir CD4 <200/mm3 and increased with age (irrespective of gender). The minimum number of consultations to be scheduled per year was 8123: 70% for the management of comorbidities with an average of six consultations/year/patient. Overall, 53% of patients should attend a proctology consultation. The minimum number of paramedical procedures to be performed was 5115. CONCLUSION: The implementation of a personalized multidisciplinary management within a single facility seems to be a suitable care model to address the needs of HIV-infected individuals.
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Submitted on : Tuesday, April 16, 2019 - 2:14:59 PM
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Isabelle Poizot-Martin, V Obry-Roguet, Olivia Zaegel-Faucher, C Lions, C Cano, et al.. HIV infection and care pathway: From guidelines to clinical practice. Médecine et Maladies Infectieuses, Elsevier Masson, 2019, 49 (1), pp.23-33. ⟨10.1016/j.medmal.2018.07.005⟩. ⟨inserm-02101017⟩

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