Propranolol 18F-FDG PET/CT: A Noninvasive Approach for Differential Diagnosis of Hibernoma and Liposarcoma.

Abstract : A 76-year-old woman was referred for F-FDG PET/CT assessment of a colorectal cancer. A 9-cm F-FDG-avid fatty mass was depicted in the right thigh, suggesting either hibernoma or liposarcoma. Because MRI could not rule out well-differentiated liposarcoma, and biopsy was difficult, surveillance was decided. Follow-up PET/CT showed an increase of F-FDG uptake in the fatty mass. We repeated PET/CT after oral administration of 60 mg of propranolol 1 hour before F-FDG injection. A dramatic decrease in F-FDG uptake was observed, strongly supporting the diagnosis of hibernoma.
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Submitted on : Monday, April 8, 2019 - 4:31:46 PM
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Renaud Ciappuccini, Stéphane Bardet, Nicolas Aide. Propranolol 18F-FDG PET/CT: A Noninvasive Approach for Differential Diagnosis of Hibernoma and Liposarcoma.. Clinical Nuclear Medicine, Lippincott, Williams & Wilkins, 2017, 42 (11), pp.879-880. ⟨10.1097/RLU.0000000000001830⟩. ⟨inserm-02093131⟩

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