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Journal articles
Plasmodium falciparum Plasmepsin 2 Duplications, West Africa
Plasmodium falciparum Plasmepsin 2 Duplications, West Africa
Abstract : Dihydroartemisinin/piperaquine (DHA/PPQ) is increasingly deployed as antimalaria drug in Africa. We report the detection in Mali of Plasmodium falciparum infections carrying plasmepsin 2 duplications (associated with piperaquine resistance) in 7/65 recurrent infections within 2 months after DHA/PPQ treatment. These findings raise concerns about the long-term efficacy of DHA/PPQ treatment in Africa.
Cited literature [20 references]
https://www.hal.inserm.fr/inserm-02093060
Contributor : Christine Dupuis Connect in order to contact the contributor
Submitted on : Monday, April 8, 2019 - 4:06:33 PM
Last modification on : Tuesday, December 15, 2020 - 3:56:02 PM
Long-term archiving on: : Tuesday, July 9, 2019 - 5:14:55 PM
Contributor : Christine Dupuis Connect in order to contact the contributor
Submitted on : Monday, April 8, 2019 - 4:06:33 PM
Last modification on : Tuesday, December 15, 2020 - 3:56:02 PM
Long-term archiving on: : Tuesday, July 9, 2019 - 5:14:55 PM