One consensual depression diagnosis tool to serve many countries: a challenge! A RAND/UCLA methodology

Patrice Nabbe 1, * Jean Yves Le Reste 1 Morgane Guillou-Landreat 1 Emilie Beck-Robert 1 Radost Assenova 2 Djurdjica Lazic 3 Slawomir Czachowski 4 Stanislava Stojanović-Špehar 3 Melida Hasanagic 5 Heidrun Lingner 6 Ana Clavería 7 Maria Isabel Fernandez San Martin 8 Agnieska Sowinska 9 Stella Argyriadou 10 Charilaos Lygidakis 11 Bernard Le Floch 1 Christa Doerr 12 Tristan Montier 13 Harm van Marwijk 14 Paul van Royen 15
Abstract : OBJECTIVE: From a systematic literature review (SLR), it became clear that a consensually validated tool was needed by European General Practitioner (GP) researchers in order to allow multi-centred collaborative research, in daily practice, throughout Europe. Which diagnostic tool for depression, validated against psychiatric examination according to the DSM, would GPs select as the best for use in clinical research, taking into account the combination of effectiveness, reliability and ergonomics? A RAND/UCLA, which combines the qualities of the Delphi process and of the nominal group, was used. GP researchers from different European countries were selected. The SLR extracted tools were validated against the DSM. The Youden index was used as an effectiveness criterion and Cronbach's alpha as a reliability criterion. Ergonomics data were extracted from the literature. Ergonomics were tested face-to-face. RESULTS: The SLR extracted 7 tools. Two instruments were considered sufficiently effective and reliable for use: the Hospital Anxiety and Depression Scale and the Hopkins Symptoms Checklist-25 (HSCL-25). After testing face-to-face, HSCL-25 was selected. A multicultural consensus on one diagnostic tool for depression was obtained for the HSCL-25. This tool will provide the opportunity to select homogeneous populations for European collaborative research in daily practice.
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Patrice Nabbe, Jean Yves Le Reste, Morgane Guillou-Landreat, Emilie Beck-Robert, Radost Assenova, et al.. One consensual depression diagnosis tool to serve many countries: a challenge! A RAND/UCLA methodology. BMC Research Notes, BioMed Central, 2018, 11 (1), pp.4. ⟨10.1186/s13104-017-3111-x⟩. ⟨inserm-02090434⟩

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