A framework for assessing immunological correlates of protection in vaccine trials, J. Infect. Dis, vol.196, pp.1304-1312, 2007. ,
Evaluating a surrogate endpoint at three levels, with application to vaccine development, Stat. Med, vol.27, pp.4758-4778, 2008. ,
DOI : 10.1002/sim.3122
URL : http://europepmc.org/articles/pmc2646675?pdf=render
The 'anti-hype' vaccine, Nat. Biotechnol, vol.35, pp.193-197, 2017. ,
Immunological mechanisms of vaccination, Nat. Immunol, vol.12, pp.509-517, 2011. ,
DOI : 10.1038/ni.2039
URL : http://europepmc.org/articles/pmc3253344?pdf=render
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy: restoring the immunogenicity of immunosilent mRNA, J. Control. Release, vol.266, pp.287-300, 2017. ,
Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity, J. Immunother, vol.34, pp.1-15, 2011. ,
DOI : 10.1097/cji.0b013e3181f7dbe8
Cationic lipids activate intracellular signaling pathways, Adv. Drug Deliv. Rev, vol.64, pp.1749-1758, 2012. ,
DOI : 10.1016/j.addr.2012.05.009
Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines, Mol. Ther, vol.21, pp.251-259, 2013. ,
Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection, Nat. Biotechnol, vol.30, pp.1210-1216, 2012. ,
Zika virus protection by a single low-dose nucleosidemodified mRNA vaccination, Nature, vol.543, pp.248-251, 2017. ,
DOI : 10.1038/nature21428
URL : https://www.nature.com/articles/nature21428.pdf
mRNA-based dendritic cell vaccines, Expert Rev. Vaccines, vol.14, pp.161-176, 2015. ,
DOI : 10.1586/14760584.2014.957684
Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation, Gene Ther, vol.18, pp.702-708, 2011. ,
Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon, Mol. Ther. Nucleic Acids, vol.5, p.326, 2016. ,
Dynamic imaging of T cell-dendritic cell interactions in lymph nodes, Science, vol.296, pp.1873-1876, 2002. ,
Routing dependent immune responses after experimental R848-adjuvated vaccination, Vaccine, vol.36, pp.1405-1413, 2018. ,
Comparison of lyophilized versus liquid modified vaccinia Ankara (MVA) formulations and subcutaneous versus intradermal routes of administration in healthy vaccinia-naive subjects, Vaccine, vol.33, pp.5225-5234, 2015. ,
Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference, Proc. Natl Acad. Sci. USA, vol.104, pp.16534-16539, 2007. ,
Design of ionizable lipids to overcome the limiting step of endosomal escape: application in the intracellular delivery of mRNA, DNA, and siRNA, J. Med. Chem, vol.59, pp.3046-3062, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01831743
Self-assembling complexes between binary mixtures of lipids with different linkers and nucleic acids promote universal mRNA, DNA and siRNA delivery, J. Control. Release, vol.249, pp.131-142, 2017. ,
DOI : 10.1016/j.jconrel.2017.01.041
URL : https://hal.archives-ouvertes.fr/inserm-01473687
Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA-protein correlations at the level of single cells, Nucleic Acids Res, vol.45, p.113, 2017. ,
Imaging viral RNA using multiply labeled tetravalent RNA imaging probes in live cells, Methods, vol.98, pp.91-98, 2016. ,
Unifying in vitro and in vivo IVT mRNA expression discrepancies in skeletal muscle via mechanotransduction, Biomaterials, vol.159, pp.189-203, 2018. ,
Efficient targeting and activation of antigen-presenting cells in vivo after modified mRNA vaccine administration in rhesus macaques, Mol. Ther, vol.25, pp.2635-2647, 2017. ,
Production of pseudoinfectious yellow fever virus with a two-component genome, J. Virol, vol.81, pp.11737-11748, 2007. ,
Role of the transmembrane domains of prM and E proteins in the formation of yellow fever virus envelope, J. Virol, vol.77, pp.813-820, 2003. ,
Fundamental limits of spatial resolution in PET, Nucl. Instrum. Methods Phys. Res. A, vol.648, pp.236-240, 2011. ,
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches, Immunity, vol.46, pp.1073-1088, 2017. ,
Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant, Vaccine, vol.31, pp.3979-3986, 2013. ,
Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes, Vaccine, vol.29, pp.1812-1823, 2011. ,
Implications of lymphatic transport to lymph nodes in immunity and immunotherapy, Annu. Rev. Biomed. Eng, vol.18, pp.207-233, 2016. ,
Regulatory immune cells in transplantation, Nat. Rev. Immunol, vol.12, pp.417-430, 2012. ,
Targeting co-stimulatory pathways: transplantation and autoimmunity, Nat. Rev. Nephrol, vol.10, pp.14-24, 2014. ,
Key roles of adjuvants in modern vaccines, Nat. Med, vol.19, pp.1597-1608, 2013. ,
Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines, Expert Opin. Drug Deliv, vol.11, pp.885-899, 2014. ,
Local innate immune responses in the vaccine adjuvant-injected muscle, Clin. Transl. Immunol, vol.5, p.74, 2016. ,
Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake, Sci. Transl. Med, vol.9, p.2094, 2017. ,