Complications of intracerebral haemorrhage, Lancet Neurol, vol.11, pp.101-118, 2012. ,
Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges, Lancet Neurol, vol.9, pp.689-701, 2010. ,
Cerebral small vessel disease: insights and opportunities from mouse models of collagen IV-related small vessel disease and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, Stroke, vol.45, pp.1215-1221, 2014. ,
Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease, N. Engl. J. Med, vol.360, pp.1729-1739, 2009. ,
Heterozygous HTRA1 mutations are associated with autosomal dominant cerebral small vessel disease, Brain, vol.138, pp.2347-2358, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01987719
Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy, Ann. Neurol, vol.80, pp.741-753, 2016. ,
Cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL), Neurology, vol.87, pp.1777-1786, 2016. ,
, Cadasil. Lancet. Neurol, vol.8, pp.643-653, 2009.
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration, Lancet Neurol, vol.12, pp.822-838, 2013. ,
Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people, Cardiovasc. Health Study Stroke, vol.27, pp.1274-1282, 1996. ,
Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study, J. Neurol. Neurosurg. Psychiatr, vol.70, pp.9-14, 2001. ,
Subclinical brain magnetic resonance imaging abnormalities predict physical functional decline in high-functioning older adults, J. Am. Geriatr. Soc, vol.53, pp.649-654, 2005. ,
Antihypertensive treatment and change in blood pressure are associated with the progression of white matter lesion volumes: the Three-City (3C)-Dijon Magnetic Resonance Imaging Study, Circulation, vol.123, pp.266-273, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-01154298
Progression of cerebral white matter lesions: 6-year results of the Austrian Stroke Prevention Study, Lancet, vol.361, pp.2046-2048, 2003. ,
The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis, BMJ, vol.341, 2010. ,
White matter lesion progression: a surrogate endpoint for trials in cerebral small-vessel disease, Neurology, vol.63, pp.139-144, 2004. ,
White matter and cognition: making the connection, J. Neurophysiol, vol.116, pp.2093-2104, 2016. ,
Myelination of the nervous system: mechanisms and functions, Annu. Rev. Cell Dev. Biol, vol.30, pp.503-533, 2014. ,
Stability of the myelin membrane, Science, vol.147, pp.1099-1107, 1965. ,
The turnover of the lipid components of myelin, J. Am. Oil Chem. Soc, vol.42, pp.1013-1018, 1965. ,
Identification of long-lived proteins reveals exceptional stability of essential cellular structures, Cell, vol.154, pp.971-982, 2013. ,
Electron microscopy of myelin: structure preservation by high-pressure freezing, Brain Res, vol.1641, pp.92-100, 2016. ,
Oligodendrocyte development and plasticity, Cold Spring Harb. Perspect. Biol, vol.8, 2015. ,
, , 2016.
, Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system, Science, vol.352, pp.1326-1329
Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain, Nat. Neurosci, vol.16, pp.668-676, 2013. ,
Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue, Cell, vol.156, pp.277-290, 2014. ,
Myelin architecture: zippering membranes tightly together, Cell. Mol. Life Sci, vol.71, pp.1265-1277, 2014. ,
A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets, Dev. Cell, vol.21, pp.445-456, 2011. ,
Myelin degeneration in multiple system atrophy detected by unique antibodies, Am. J. Pathol, vol.153, pp.735-744, 1998. ,
Loss of myelin basic protein function triggers myelin breakdown in models of demyelinating diseases, Cell Rep, vol.16, pp.314-322, 2016. ,
Biology of oligodendrocyte and myelin in the mammalian central nervous system, Physiol. Rev, vol.81, pp.871-927, 2001. ,
Oligodendrocyte dynamics in the healthy adult CNS: evidence for myelin remodeling, Neuron, vol.77, pp.873-885, 2013. ,
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain, Science, vol.344, p.1252304, 2014. ,
Impaired adult myelination in the prefrontal cortex of socially isolated mice, Nat. Neurosci, vol.15, pp.1621-1623, 2012. ,
A critical period for social experience-dependent oligodendrocyte maturation and myelination, Science, vol.337, pp.1357-1360, 2012. ,
Diffusion tensor imaging of white matter tract evolution over the lifespan, Neuroimage, vol.60, pp.340-352, 2012. ,
Assessment of normal myelination with magnetic resonance imaging, Semin. Neurol, vol.32, pp.15-28, 2012. ,
Dynamics of oligodendrocyte generation and myelination in the human brain, Cell, vol.159, pp.766-774, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01092151
Oligodendrocytes, their progenitors and other neuroglial cells in the aging primate cerebral cortex, Cereb. Cortex, vol.14, pp.995-1007, 2004. ,
The effects of normal aging on myelin and nerve fibers: a review, J. Neurocytol, vol.31, pp.581-593, 2002. ,
Age-related myelin degradation burdens the clearance function of microglia during aging, Nat. Neurosci, vol.19, pp.995-998, 2016. ,
Axonal swellings and degeneration in mice lacking the major proteolipid of myelin, Science, vol.280, pp.1610-1613, 1998. ,
Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination, Nat. Genet, vol.33, pp.366-374, 2003. ,
, Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity, Nature, vol.485, pp.517-521
Oligodendroglia metabolically support axons and contribute to neurodegeneration, Nature, vol.487, pp.443-448, 2012. ,
Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism, Neuron, vol.91, pp.119-132, 2016. ,
Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system, Neuroscience, vol.168, pp.982-1008, 2010. ,
Genetic and physiological evidence that oligodendrocyte gap junctions contribute to spatial buffering of potassium released during neuronal activity, Lancet Neurol, vol.26, pp.973-985, 2006. ,
Brain white matter oedema due to ClC-2 chloride channel deficiency: an observational analytical study, Lancet Neurol, vol.12, pp.659-668, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-00842764
Microvasculature of the human cerebral white matter: arteries of the deep white matter, Neuropathology, vol.23, pp.111-118, 2003. ,
Features of the cerebral vascular pattern that predict vulnerability to perfusion or oxygenation deficiency: an anatomic study, Am. J. Neuroradiol, vol.11, pp.431-439, 1990. ,
The microvasculature of the cerebral white matter: arteries of the subcortical white matter, J. Neuropathol. Exp. Neurol, vol.62, pp.154-161, 2003. ,
The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat, J. Neurochem, vol.28, pp.897-916, 1977. ,
The energetics of CNS white matter, J. Neurosci, vol.32, pp.356-371, 2012. ,
Impact of cerebral white matter changes on functionality in older adults: an overview of the LADIS Study results and future directions, Geriatr. Gerontol. Int, vol.15, issue.1, pp.10-16, 2015. ,
White matter lesions as a predictor of depression in the elderly: the 3C-Dijon study, Biol. Psychiatry, vol.63, pp.663-669, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00175779
White-matter lesions without lacunar infarcts in CADASIL, J. Alzheimers Dis, vol.29, pp.903-911, 2012. ,
Reaction time is a marker of early cognitive and behavioral alterations in pure cerebral small vessel disease, J. Alzheimers Dis, vol.47, pp.413-419, 2015. ,
Heterogeneity in age-related white matter changes, Acta Neuropathol, vol.122, pp.171-185, 2011. ,
A novel hereditary extensive vascular leukoencephalopathy mapping to chromosome 20q13, Neurology, vol.79, pp.2283-2287, 2012. ,
MRI features of pontine autosomal dominant microangiopathy and leukoencephalopathy (PADMAL), J. Neuroimaging, vol.20, pp.134-140, 2010. ,
Clinical severity in CADASIL related to ultrastructural damage in white matter: in vivo study with diffusion tensor MRI, Stroke, vol.30, pp.2637-2643, 1999. ,
URL : https://hal.archives-ouvertes.fr/hal-00349907
Monitoring disease progression in CADASIL with diffusion magnetic resonance imaging: a study with whole brain histogram analysis, Stroke, vol.33, pp.2902-2908, 2002. ,
URL : https://hal.archives-ouvertes.fr/hal-00349703
Strategic white matter tracts for processing speed deficits in age-related small vessel disease, Neurology, vol.82, pp.1946-1950, 2014. ,
Assessing white matter ischemic damage in dementia patients by measurement of myelin proteins, J. Cereb. Blood Flow Metab, vol.33, pp.1050-1057, 2013. ,
Microvascular pathology and morphometrics of sporadic and hereditary small vessel diseases of the brain, Brain Pathol, vol.24, pp.495-509, 2014. ,
Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia, Brain, vol.139, pp.242-258, 2016. ,
Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations, J. Neurol. Neurosurg. Psychiatr, vol.82, pp.126-135, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00584605
Postmortem MR imaging of formalin-fixed human brain, Neuroimage, vol.21, pp.1585-1595, 2004. ,
Do brain T2/FLAIR white matter hyperintensities correspond to myelin loss in normal aging? A radiologic-neuropathologic correlation study, Acta Neuropathol. Commun, vol.1, p.14, 2013. ,
Neuropathological correlates of temporal pole white matter hyperintensities in CADASIL, Stroke, vol.40, 2004. ,
Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease, J. Clin. Invest, vol.120, pp.433-445, 2010. ,
White matter hyperintensity volume and cerebral perfusion in older individuals with hypertension using arterial spin-labeling, Acta Neuropathol. Commun, vol.2, 2009. ,
Vascular dysfunction in leukoaraiosis, Am. J. Neuroradiol, vol.37, pp.2258-2264, 2016. ,
Cerebral blood flow in small vessel disease: a systematic review and meta-analysis, J. Cereb. Blood Flow Metab, vol.36, pp.1653-1667, 2016. ,
Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolus tracking, Stroke, vol.31, pp.1904-1912, 2000. ,
URL : https://hal.archives-ouvertes.fr/hal-00349831
Reduced blood flow in normal white matter predicts development of leukoaraiosis, J. Cereb. Blood Flow Metab, vol.35, pp.0-16, 2015. ,
Longitudinal relationship between cerebral small-vessel disease and cerebral blood flow: the second manifestations of arterial disease-magnetic resonance study, Stroke, vol.46, pp.1233-1238, 2015. ,
White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion, Stroke, vol.35, pp.2598-2603, 2004. ,
Substantial reduction of parenchymal cerebral blood flow in mice with bilateral common carotid artery stenosis, Sci. Rep, vol.6, p.32179, 2016. ,
Matrix metalloproteinase-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents, Stroke, vol.37, pp.2816-2823, 2006. ,
Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice, Ann. Neurol, vol.79, pp.387-403, 2016. ,
The Cerebral Circulation, Morgan & Claypool Life Sciences, 2009. ,
Impaired dynamic cerebrovascular response to hypercapnia predicts development of white matter hyperintensities, Neuroimage Clin, vol.11, pp.796-801, 2016. ,
Development of white matter hyperintensity is preceded by reduced cerebrovascular reactivity, Ann. Neurol, vol.80, pp.277-285, 2016. ,
Cerebrovascular reactivity is a main determinant of white matter hyperintensity progression in CADASIL, Am. J. Neuroradiol, vol.30, pp.1244-1247, 2009. ,
Hypertension and cerebrovascular dysfunction, Cell Metab, vol.7, pp.476-484, 2008. ,
Functional vascular contributions to cognitive impairment and dementia (VCID): mechanisms and consequences of cerebral microvascular dysfunction in aging, Am. J. Physiol. Heart Circ. Physiol, vol.312, pp.1-20, 2017. ,
Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL, Brain, vol.136, pp.1830-1845, 2013. ,
Establishment and dysfunction of the blood-brain barrier, Cell, vol.163, pp.1064-1078, 2015. ,
Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis, Neurobiol. Aging, vol.30, pp.337-352, 2009. ,
Blood-brain barrier dysfunction in Binswanger's disease; an immunohistochemical study, Acta Neuropathol, vol.95, pp.78-84, 1998. ,
Perivascular deposits of serum proteins in cerebral cortex in vascular dementia, Acta Neuropathol, vol.66, pp.292-298, 1985. ,
, CADASIL and CARASIL. Brain Pathol, vol.24, pp.525-544, 2014.
Tracer kinetic modelling for DCE-MRI quantification of subtle blood-brain barrier permeability, Neuroimage, vol.125, pp.446-455, 2016. ,
Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis, J. Neurol. Neurosurg. Psychiatr, vol.81, pp.192-197, 2010. ,
Long-term blood-brain barrier permeability changes in Binswanger disease, Stroke, vol.46, pp.2413-2418, 2015. ,
Integrity of normal-appearing white matter: influence of age, visible lesion burden and hypertension in patients with small-vessel disease, J. Cereb. Blood Flow Metab. Mar, vol.1, 2016. ,
Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review, Int. J. Stroke, vol.6, pp.434-444, 2011. ,
Cerebrovascular lesions in stroke-prone spontaneously hypertensive rats, Acta Neuropathol, vol.68, pp.284-294, 1985. ,
Cyst formation and glial response in the brain lesions of stroke-prone spontaneously hypertensive rats, Acta Neuropathol, vol.76, pp.441-450, 1988. ,
Oligodendrocyte precursors migrate along vasculature in the developing nervous system, Science, vol.351, pp.379-384, 2016. ,
Adrenomedullin promotes differentiation of oligodendrocyte precursor cells into myelin-basic-protein expressing oligodendrocytes under pathological conditions in vitro, Stem Cell Res, vol.15, pp.68-74, 2015. ,
Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis, Cell, vol.158, pp.383-396, 2014. ,
An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells, J. Neurosci, vol.29, pp.4351-4355, 2009. ,
Integrin-growth factor interactions as regulators of oligodendroglial development and function, CrossRef Clinical Science, vol.49, p.0, 2005. ,
Perturbations of the cerebrovascular matrisome: a convergent mechanism in small vessel disease of the brain?, J. Cereb. Blood Flow Metab, vol.36, pp.143-157, 2016. ,
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid ?, Sci. Transl, 2012. ,
Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain, J. Neurosci, vol.33, pp.18190-18199, 2013. ,
Impairment of paravascular clearance pathways in the aging brain, The Author(s), vol.76, pp.845-861, 2014. ,