, Food Labeling: Health Claims; Soluble Fiber from Certain Foods and Coronary Heart Disease, US Food and Drug Administration, vol.63, 1998.

Y. Vigouroux and . Le,

D. A. Bender and A. E. Bender, Benders' Dictionary of Nutrition and Food Technology, 1999.

S. H. Lee, I. M. Chung, Y. S. Cha, and Y. Park, Millet consumption decreased serum concentration of triglyceride and C-reactive protein but not oxidative status in hyperlipidemic rats, Nutr Res, vol.30, pp.290-296, 2010.

S. Shobana, M. R. Harsha, K. Platel, K. Srinivasan, and N. G. Malleshi, Amelioration of hyperglycaemia and its associated complications by finger millet (Eleusine coracana L.) seed coat matter in streptozotocin-induced diabetic rats, Br J Nutr, vol.104, pp.1787-95, 2010.

K. Shukla and S. Srivastava, Evaluation of finger millet incorporated noodles for nutritive value and glycemic index, J Food Sci Technol, vol.51, pp.527-561, 2014.

A. Chandrasekara and F. Shahidi, Content of insoluble bound phenolics in millets and their contribution to antioxidant capacity, J Agric Food Chem, vol.58, pp.6706-6720, 2010.

J. A. Duke, Biological Active Phytochemicals and Their Activities, 1992.

M. Watanabe, Antioxidative phenolic compounds from Japanese barnyard millet (Echinochloa utilis) grains, J Agric Food Chem, vol.47, pp.4500-4505, 1999.

S. J. Van-rensburg, Epidemiological and dietary evidence for a specific nutritional predisposition to esophageal cancer, J Natl Cancer Inst, vol.67, pp.243-51, 1981.

F. Chen, P. Cole, Z. Mi, and L. Y. Xing, Corn and wheat-flour consumption and mortality from esophageal cancer in Shanxi, China, Int J Cancer, vol.53, pp.902-908, 1993.

A. Nani, M. Belarbi, Z. Soualem, F. Z. Ghanemi, N. Borsali et al., Study of the impact of millet (Pennisetum glaucum) on the glucidic metabolism in diabetic rats, Ann Biol Res, vol.2, pp.21-24, 2011.

V. S. Nambiar, J. J. Dhaduk, N. Sareen, T. Shahu, and R. Desai, Potential Functional Implications of Pearl millet (Pennisetum glaucum) in Health and Disease, J Appl Pharm Sci, vol.01, pp.62-69, 2011.

K. K. Adom, M. E. Sorrells, and R. H. Liu, Phytochemical profiles and antioxidant activity of wheat varieties, J Agric Food Chem, vol.51, pp.7825-7859, 2003.

M. F. Andreasen, L. P. Christensen, A. S. Meyer, and A. Hansen, Content of phenolic acids and ferulic acid dehydrodimers in 17 rye (Secale cereale L.) varieties, J Agric Food Chem, vol.48, pp.2837-2879, 2000.

B. J. Lloyd, T. J. Siebenmorgen, and K. W. Beers, Effects of commercial processing on antioxidants in rice bran, Cereal Chem, vol.77, pp.551-556, 2000.

M. Maillard and C. Berset, Evolution of antioxidant activity during kilning: role of insoluble bound phenolic acids of barley and malt, J Agric Food Chem, vol.43, pp.1789-93, 1995.

E. Middleton, Effect of plant flavonoids on immune and inflammatory cell function, Adv Exp Med Biol, vol.439, pp.175-82, 1998.

A. Serrano, C. Palacios, G. Roy, C. Cespon, M. Villar et al., Derivatives of gallic acid induce apoptosis in tumoral cell lines and inhibit lymphocyte proliferation, Arch Biochem Biophys, vol.350, pp.49-54, 1998.

E. A. Miles, P. Zoubouli, and P. C. Calder, Effects of polyphenols on human Th1 and Th2 cytokine production, Clin Nutr, vol.24, pp.780-784, 2005.

R. González, I. Ballester, R. López-posadas, M. D. Suárez, A. Zarzuelo et al., Effects of flavonoids and other polyphenols on inflammation, Crit Rev Food Sci Nutr, vol.51, pp.331-62, 2011.

F. Ghiringhelli, C. Rebe, A. Hichami, and D. Delmas, Immunomodulation and antiinflammatory roles of polyphenols as anticancer agents, Anticancer Agents Med Chem, vol.12, pp.852-73, 2012.

P. S. Tappia and R. F. Grimble, Complex modulation of cytokine induction by endotoxin and tumour necrosis factor from peritoneal macrophages of rats by diets containing fats of different saturated, monounsaturated and polyunsaturated fatty acid composition, Clin Sci, vol.87, pp.173-181, 1994.

F. A. Wallace, S. J. Neely, E. A. Miles, and P. C. Calder, Dietary fats affect macrophagemediated cytotoxicity towards tumour cells, Immunol Cell Biol, vol.78, pp.40-48, 2000.

D. S. Kelley, Modulation of human immune and inflammatory responses by dietary fatty acids, Nutrition, vol.17, pp.669-73, 2001.

C. R. Cavaglieri, A. Nishiyama, L. C. Fernandes, R. Curi, E. A. Miles et al., Differential effects of short-chain fatty acids on proliferation and production of pro-and anti-inflammatory cytokines by cultured lymphocytes, Life Sci, vol.73, pp.1683-90, 2003.

T. Kurita-ochiai, S. Seto, and K. Ochiai, Role of cell-cell communication in inhibiting butyric acid-induced T-cell apoptosis Infections, Infect Immun, vol.72, pp.5947-54, 2004.

A. N. Yusufi, J. Cheng, M. A. Thompson, H. J. Walker, C. E. Gray et al., Differential effects of low-dose docosahexaenoic acid and eicosapentaenoic acid on the regulation of mitogenic signaling pathways in mesangial cells, J Lab Clin Med, vol.141, pp.318-347, 2003.

I. Lestienne, M. Buisson, and V. Lullien-pellerin, Losses of nutrients and anti-nutritional factors during abrasive decortication of two pearl millet cultivars (Pennisetum glaucum), Food Chem, vol.100, pp.1316-1339, 2007.

C. M. Liyana-pathirana and F. Shahidi, Importance of insoluble-bound phenolics to antioxidant properties of wheat, J Agric Food Chem, vol.54, pp.1256-64, 2006.

O. Folin and V. Ciocalteu, On tyrosine and tryptophane determinations in proteins, J Biol Chem, vol.27, pp.627-50, 1927.

G. Miliauskas, P. R. Venskutonis, and T. A. Van-beek, Screening of radical scavenging activity of some medicinal and aromatic plant extracts, Food Chem, vol.85, pp.231-238, 2004.

A. Hara and N. S. Radin, Lipid extraction of tissues with a low-toxicity solvent, Anal Biochem, vol.90, pp.420-426, 1978.

C. Triboulot, A. Hichami, A. Denys, and N. A. Khan, Dietary (n-3) Polyunsaturated Fatty Acids Exert Antihypertensive Effects by Modulating Calcium Signaling in T Cells of Rats, J Nutr, vol.131, pp.2364-2373, 2001.

A. Bonin and N. A. Khan, Regulation of calcium signaling by docosahexaenoic acid in human T-cells: implication of CRAC channels, J Lipid Res, vol.41, pp.277-84, 2000.

A. E. Nel, C. Hanekom, A. Rheeder, K. Williams, S. Pollack et al., Stimulation of MAP-2 kinase activity in T lymphocytes by anti-CD3 or anti-Ti monoclonal antibody is partially dependent on protein kinase C, J Immunol, vol.144, pp.2683-2692, 1990.

A. Yessoufou, A. Plé, K. Moutairou, A. Hichami, and N. A. Khan, Docosahexaenoic acid reduces suppressive and migratory functions of CD4 + CD25+ regulatory T-cells, J Lipid Res, vol.50, pp.2377-88, 2009.

D. K. Sojka, D. Bruniquel, R. H. Schwartz, and N. J. Singh, IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition, J Immunol, vol.172, pp.6136-6179, 2004.

S. Abdoul-azize, M. Bendahmane, A. Hichami, G. Dramane, A. M. Simonin et al., Effects of Zizyphus lotus L. (Desf.) polyphenols on Jurkat cell signaling and proliferation, Int Immunopharmacol, vol.15, pp.364-71, 2013.

V. Aires, S. Adote, A. Hichami, K. Moutairou, E. E. Boustani et al., Modulation of intracellular calcium concentrations and T cell activation by prickly pear polyphenols, Mol Cell Biochem, vol.260, pp.103-113, 2004.

O. Thastrup, P. J. Cullen, B. K. Drobak, M. R. Hanley, and A. P. Dawson, Thapsigargin, a tumor promoter, discharges intracellular Ca 2+ stores by specific inhibition of the endoplasmic reticulum Ca 2+ -ATPase, Proc Natl Acad Sci, vol.87, pp.2466-70, 1990.

Z. Pan, X. Zhao, and M. Brotto, Fluorescence-based Measurement of Store-operated Calcium Entry in Live Cells: from Cultured Cancer Cell to Skeletal Muscle Fiber, J Vis Exp, vol.10, pp.3415-791, 2012.

L. Dykes and L. W. Rooney, Sorghum and millet phenols and antioxidants, J Cereal Sci, vol.44, pp.236-51, 2006.

S. Ragaee, M. El-sayed, and A. Mn, Antioxydant activity and nutrient composition of selected cereals for food use, Food Chem, vol.98, pp.32-40, 2006.

G. Hithamani and K. Srinivasan, Effect of domestic processing on the polyphenol content and bioaccessibility in finger millet (Eleusine coracana) and pearl millet (Pennisetum glaucum), Food Chem, vol.164, pp.55-62, 2014.

F. Shahidi and A. Chandrasekara, Millet grain phenolics and their role in disease risk reduction and health promotion: A review, J Funct Foods, vol.5, pp.570-81, 2013.

M. Daniel, M. Denni, and D. Chauhan, Polyphenols, phospholipids and fixed oil composition of pearl millet, IJPLS, vol.3, pp.2098-102, 2012.

Y. Baba-hamed, A. Medjdoub, M. Kara, B. Merzouk, H. Villemin et al., 6-Dihydro-2H-pyranones and 5,6-dihydro-2H-pyridones and their derivatives modulate in vitro human T lymphocyte function, Mol Cell Biochem, vol.5, pp.23-33, 2012.

J. Christiansen, G. Farm, R. Eid-forest, C. Anderson, K. Cederbrant et al., Interferon-gamma secreted from peripheral blood mononuclear cells as a possible diagnostic marker for allergic contact dermatitis to gold, Contact Dermatitis, vol.55, pp.101-113, 2006.

E. Donnadieu, G. Bismuth, and A. Trautmann, X Calcium fluxes in T-lymphocytes, J Biol Chem, vol.267, pp.25864-72, 1992.

P. A. Negulescu, N. Shastri, and M. D. Cahalan, Intracellular calcium dependence of gene expression in single T lymphocytes, Proc Natl Acad Sci, vol.91, pp.2873-2880, 1994.

Y. Yin, F. Y. Gong, X. X. Wu, Y. Sun, Y. H. Li et al., Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita, J Ethnopharmacol, vol.120, pp.1-6, 2008.

Z. D. Liang, Y. Y. Zeng, X. Y. Huang, and F. He, Effect of Apigenin on proliferation, cell cycle and apoptosis of mouse T cells in vitro, Chinese J Cell Mol Immunol, vol.24, pp.337-377, 2008.

E. A. Hudson, P. A. Dinh, T. Kokubun, M. S. Simmonds, and A. Gescher, Characterization of potentially chemopreventive phenols in extracts of brown rice that inhibit the growth of human breast and colon cancer cells, Cancer Epidemiol Biomarkers Prev, vol.9, pp.1163-70, 2000.

L. R. Ferguson, I. F. Lim, A. E. Pearson, J. Ralph, and P. J. Harris, Bacterial antimutagenesis by hydroxycinnamic acids from plant cell walls, Mutat Res, vol.542, pp.49-58, 2003.
DOI : 10.1016/j.mrgentox.2003.08.005

C. Luceri, F. Guglielmi, M. Lodovici, L. Giannini, L. Messerini et al., Plant phenolic 4-coumaric acid protects against intestinal inflammation in rats, Scand J Gastroenterol, vol.39, pp.1128-1161, 2004.

D. Atluru, T. M. Jackson, and S. Atluru, Genistein, a selective protein tyrosine kinase inhibitor, inhibits interleukin-2 and leukotriene B4 production from human mononuclear cells, Clin Immunol Immunopathol, vol.59, pp.379-87, 1991.
DOI : 10.1016/0090-1229(91)90033-7
URL : https://deepblue.lib.umich.edu/bitstream/2027.42/29309/1/0000372.pdf

M. A. Devi and N. P. Das, In vitro effects of natural plant polyphenols on the proliferation of normal and abnormal human lymphocytes and their secretions of interleukin-2, Cancer Lett, vol.69, pp.191-197, 1993.

X. Gao, Y. X. Xu, N. Janakiraman, R. A. Chapman, and S. C. Gautman, Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cellmediated cytotoxicity, and cytokine production, Biochem Pharmacol, vol.62, pp.1299-308, 2001.

I. Okamoto, K. Iwaki, S. Koya-miyata, T. Tanimoto, K. Kohno et al., The flavonoid kaempferol suppresses the graftversus-host reaction by inhibiting type 1 cytokine production and CD8+ T cell engraftment, Clin Immunol, vol.103, pp.132-176, 2002.

Y. J. Wang, M. H. Pan, A. L. Cheng, L. I. Lin, Y. S. Ho et al., Stability of curcumin in buffer solutions and characterization of its degradation products, J Pharm Biomed Anal, vol.15, pp.1867-76, 1997.

X. Ma, Z. Jiang, and C. Lai, Significance for Human Health of Increasing n-3PUFA Content in Pork, Crit Rev Food Sci Nutr, 2015.

Y. Liu, L. Gong, D. Li, Z. Feng, L. Zhao et al., Effects of fish oil on lymphocyte proliferation, cytokine production and intracellular signaling in weanling pigs, Arch Tierernahr, vol.57, pp.151-65, 2003.

M. F. Cury-boaventura, R. Gorjão, T. M. De-lima, P. Newsholme, and R. Curi, Comparative toxicity of oleic and linoleic acid on human lymphocytes, Life Sci, vol.78, pp.1448-56, 2006.
DOI : 10.1016/j.lfs.2005.07.038

A. Denys, A. Hichami, and N. A. Khan, n-3 PUFAs modulate T-cell activation via protein kinase C-? and -? and the NF-?B signaling pathway, J Lipid Res, vol.46, pp.752-760, 2005.

G. R. Crabtree, Generic signals and specific outcomes: Signaling through Ca 2+ , calcineurin, and NF-AT, Cell, vol.96, pp.611-615, 1999.
DOI : 10.1016/s0092-8674(00)80571-1
URL : https://doi.org/10.1016/s0092-8674(00)80571-1

D. Cantrell, T cell antigen receptor signal transduction pathways, Annu Rev Immunol, vol.14, pp.259-74, 1996.
DOI : 10.1146/annurev.immunol.14.1.259

T. Neuhaus, S. Pabst, S. Stier, A. A. Weber, K. Schrör et al., Inhibition of the vascular-endothelial growth factor-induced intracellular signaling and mitogenesis of human endothelial cells by epigallocatechin-3 gallate, Eur J Pharmacol, vol.483, pp.223-230, 2004.

Y. Hou, J. Yang, G. Zhao, and Y. J. Yuan, Ferulic acid inhibits endothelial cell proliferation through NO down-regulating ERK1/2 pathway, Cell Biochem, vol.93, pp.1203-1212, 2004.
DOI : 10.1002/jcb.20281