Q. T. Ostrom, L. Bauchet, F. G. Davis, I. Deltour, J. L. Fisher et al., The epidemiology of glioma in adults: a ''state of the science" review, vol.16, pp.896-913, 2014.

R. Stupp, W. P. Mason, M. J. Van-den-bent, M. Weller, B. Fisher et al., European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups, National Cancer Institute of Canada Clinical Trials Group, Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma, N. Engl. J. Med, vol.352, pp.987-996, 2005.

R. Stupp, M. E. Hegi, W. P. Mason, M. J. Van-den-bent, M. J. Taphoorn et al.,

. Mirimanoff, European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups, National Cancer Institute of Canada Clinical Trials Group, Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial, Lancet Oncol, vol.10, pp.459-466, 2009.

J. Lemée, A. Clavreul, and P. Menei, Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone, Neuro-Oncol, vol.17, pp.1322-1332, 2015.

M. Niyazi, M. Brada, A. J. Chalmers, S. E. Combs, S. C. Erridge et al., ESTRO-ACROP guideline ''target delineation of glioblastomas, Radiother. Oncol, vol.118, pp.35-42, 2016.

K. Petrecca, M. Guiot, V. Panet-raymond, and L. Souhami, Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma, J. Neurooncol, vol.111, pp.19-23, 2013.

C. Angelucci, A. D'alessio, G. Lama, E. Binda, A. Mangiola et al., Cancer stem cells from peritumoral tissue of glioblastoma multiforme: the possible missing link between tumor development and progression, Oncotarget, vol.9, pp.28116-28130, 2018.

M. Glas, B. H. Rath, M. Simon, R. Reinartz, A. Schramme et al., Residual tumor cells are unique cellular targets in glioblastoma, Ann. Neurol, vol.68, pp.264-269, 2010.

S. G. Piccirillo, S. Dietz, B. Madhu, J. Griffiths, S. J. Price et al., Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin, Br. J. Cancer, vol.107, pp.462-468, 2012.

W. Jabbour and D. , Wion, Extent of Resection and Survival in Glioblastoma Multiforme, JAMA Oncol, vol.2, p.1509, 2016.

J. Lemée, A. Clavreul, M. Aubry, E. Com, M. De-tayrac et al., Characterizing the peritumoral brain zone in glioblastoma: a multidisciplinary analysis, J. Neurooncol, vol.122, pp.53-61, 2015.

A. Clavreul, A. Etcheverry, A. Chassevent, V. Quillien, T. Avril et al., Grand Ouest Glioma Project Network, P. Menei, Isolation of a new cell population in the glioblastoma microenvironment, J. Neurooncol, vol.106, pp.493-504, 2012.

A. Clavreul, C. Guette, R. Faguer, C. Tétaud, A. Boissard et al., Glioblastoma-associated stromal cells (GASCs) from histologically normal surgical margins have a myofibroblast phenotype and angiogenic properties, J. Pathol, vol.233, pp.74-88, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01064615

A. Clavreul, A. Etcheverry, C. Tétaud, A. Rousseau, T. Avril et al., Identification of two glioblastoma-associated stromal cell subtypes with different carcinogenic properties in histologically normal surgical margins, J. Neurooncol, vol.122, pp.1-10, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01117114

L. Hamard, D. Ratel, L. Selek, F. Berger, B. Van-der-sanden et al., The brain tissue response to surgical injury and its possible contribution to glioma recurrence, J. Neurooncol, vol.128, pp.1-8, 2016.
URL : https://hal.archives-ouvertes.fr/inserm-01342471

B. Van-der-sanden, F. Appaix, F. Berger, L. Selek, J. Issartel et al., Translation of the ecological trap concept to glioma therapy: the cancer cell trap concept, Future Oncol, vol.9, pp.817-824, 2013.
URL : https://hal.archives-ouvertes.fr/inserm-00851156

J. L. Shah, G. Li, J. L. Shaffer, M. I. Azoulay, I. C. Gibbs et al., Stereotactic Radiosurgery and Hypofractionated Radiotherapy for Glioblastoma, Neurosurgery, vol.82, pp.24-34, 2018.

Q. Chai, Y. Jiao, and X. Yu, Hydrogels for Biomedical Applications: Their Characteristics and the Mechanisms behind Them, vol.3, p.6, 2017.

S. M. Kabir, P. P. Sikdar, B. Haque, M. A. Bhuiyan, A. Ali et al., Cellulosebased hydrogel materials: chemistry, properties and their prospective applications, Prog. Biomater, vol.7, pp.153-174, 2018.

G. F. Picheth, C. L. Pirich, M. R. Sierakowski, M. A. Woehl, C. N. Sakakibara et al., Bacterial cellulose in biomedical applications: a review, vol.104, pp.97-106, 2017.

M. L. Cacicedo, I. E. León, J. S. Gonzalez, L. M. Porto, V. A. Alvarez et al., Modified bacterial cellulose scaffolds for localized doxorubicin release in human colorectal HT-29 cells, Colloids Surf. B Biointerfaces, vol.140, pp.421-429, 2016.

M. L. Cacicedo, M. C. Castro, I. Servetas, L. Bosnea, K. Boura et al., Progress in bacterial cellulose matrices for biotechnological applications, Bioresour. Technol, vol.213, pp.172-180, 2016.

M. M. Abeer, M. C. Mohd-amin, and C. Martin, A review of bacterial cellulose-based drug delivery systems: their biochemistry, current approaches and future prospects, J. Pharm. Pharmacol, vol.66, pp.1047-1061, 2014.

M. L. Cacicedo, G. A. Islan, I. E. León, V. A. Álvarez, I. Chourpa et al., Bacterial cellulose hydrogel loaded with lipid nanoparticles for localized cancer treatment, Colloids Surf. B Biointerfaces, vol.170, pp.596-608, 2018.
URL : https://hal.archives-ouvertes.fr/hal-01864033

M. L. Cacicedo, G. A. Islan, M. F. Drachemberg, V. A. Alvarez, L. C. Bartel et al., Hybrid bacterial cellulose-pectin films for delivery of bioactive molecules, New J. Chem, vol.42, pp.7457-7467, 2018.

Y. Pötzinger, D. Kralisch, and D. Fischer, Bacterial nanocellulose: the future of controlled drug delivery?, Ther Deliv, vol.8, pp.753-761, 2017.

R. F. Barth and B. Kaur, Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas, J. Neurooncol, vol.94, pp.299-312, 2009.

A. Clavreul, M. Delhaye, E. Jadaud, and P. Menei, Effects of syngeneic cellular vaccinations alone or in combination with GM-CSF on the weakly immunogenic F98 glioma model, J. Neurooncol, vol.79, pp.9-17, 2006.

M. L. Cacicedo, K. Cesca, V. E. Bosio, L. M. Porto, and G. R. Castro, Self-assembly of carrageenin-CaCO3 hybrid microparticles on bacterial cellulose films for doxorubicin sustained delivery, J. Appl. Biomed, vol.13, pp.239-248, 2015.

E. Goldschmidt, M. Cacicedo, S. Kornfeld, M. Valinoti, M. Ielpi et al., Construction and in vitro testing of a cellulose dura mater graft, Neurol. Res, vol.38, pp.25-31, 2016.

L. Stoppini, P. A. Buchs, and D. Muller, A simple method for organotypic cultures of nervous tissue, J. Neurosci. Methods, vol.37, pp.173-182, 1991.

P. J. Basser and D. K. Jones, Diffusion-tensor MRI: theory, experimental design and data analysis-a technical review, NMR Biomed, vol.15, pp.456-467, 2002.

G. P. Winston, The physical and biological basis of quantitative parameters derived from diffusion MRI, Quant, Imaging Med. Surg, vol.2, pp.254-265, 2012.

A. Beliveau, G. Thomas, J. Gong, Q. Wen, and A. Jain, Aligned nanotopography promotes a migratory state in glioblastoma multiforme tumor cells, Sci. Rep, vol.6, p.26143, 2016.

A. Jain, M. Betancur, G. D. Patel, C. M. Valmikinathan, V. J. Mukhatyar et al., Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres, Nat. Mater, vol.13, pp.308-316, 2014.

J. Johnson, M. O. Nowicki, C. H. Lee, E. A. Chiocca, M. S. Viapiano et al., Quantitative analysis of complex glioma cell migration on electrospun polycaprolactone using time-lapse microscopy, Tissue Eng. Part C Methods, vol.15, pp.531-540, 2009.

F. M. Kievit, A. Cooper, S. Jana, M. C. Leung, K. Wang et al., Aligned chitosan-polycaprolactone polyblend nanofibers promote the migration of glioblastoma cells, Adv. Healthc. Mater, vol.2, pp.1651-1659, 2013.

H. Bäckdahl, G. Helenius, A. Bodin, U. Nannmark, B. R. Johansson et al., Mechanical properties of bacterial cellulose and interactions with smooth muscle cells, Biomaterials, issue.27, pp.2141-2149, 2006.

M. Paolillo, M. Serra, and S. Schinelli, Integrins in glioblastoma: Still an attractive target?, Pharmacol Res, vol.113, pp.55-61, 2016.

G. Tabatabai, J. Tonn, R. Stupp, and M. Weller, The role of integrins in glioma biology and anti-glioma therapies, Curr. Pharm. Des, vol.17, pp.2402-2410, 2011.

R. A. Pértile, S. Moreira, R. M. Gil-da-costa, A. Correia, L. Guãrdao et al., Bacterial cellulose: long-term biocompatibility studies, J. Biomater. Sci. Polym. Ed, vol.23, pp.1339-1354, 2012.

L. Tang and J. W. Eaton, Inflammatory responses to biomaterials, Am. J. Clin. Pathol, vol.103, pp.466-471, 1995.
DOI : 10.1093/ajcp/103.4.466

W. J. Hu, J. W. Eaton, T. P. Ugarova, and L. Tang, Molecular basis of biomaterialmediated foreign body reactions, Blood, vol.98, pp.1231-1238, 2001.
DOI : 10.1182/blood.v98.4.1231

V. Jadhav and J. H. Zhang, Surgical brain injury: prevention is better than cure, Front. Biosci, vol.13, pp.3793-3797, 2008.
DOI : 10.2741/2968

M. Ul-islam, T. Khan, and J. K. Park, Water holding and release properties of bacterial cellulose obtained by in situ and ex situ modification, Carbohydr. Polym, vol.88, pp.596-603, 2012.
DOI : 10.1016/j.carbpol.2012.01.006

G. Helenius, H. Bäckdahl, A. Bodin, U. Nannmark, P. Gatenholm et al., In vivo biocompatibility of bacterial cellulose, J. Biomed. Mater. Res. A, vol.76, pp.431-438, 2006.
DOI : 10.1002/jbm.a.30570

F. G. Torres, S. Commeaux, and O. P. Troncoso, Biocompatibility of bacterial cellulose based biomaterials, J. Funct. Biomater, vol.3, pp.864-878, 2012.
DOI : 10.3390/jfb3040864

URL : http://www.mdpi.com/2079-4983/3/4/864/pdf

A. Valster, N. L. Tran, M. Nakada, M. E. Berens, A. Y. Chan et al., Cell migration and invasion assays, Methods San Diego Calif, vol.37, pp.208-215, 2005.
DOI : 10.1016/j.ymeth.2005.08.001

A. Müller, Z. Ni, N. Hessler, F. Wesarg, F. A. Müller et al., The biopolymer bacterial nanocellulose as drug delivery system: investigation of drug loading and release using the model protein albumin, J. Pharm. Sci, vol.102, pp.579-592, 2013.

V. P. Ferrer, V. M. Neto, and R. Mentlein, Glioma infiltration and extracellular matrix: key players and modulators, Glia, 2018.
DOI : 10.1002/glia.23309

J. B. Wolinsky, Y. L. Colson, and M. W. Grinstaff, Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers, J. Control. Release, vol.159, pp.14-26, 2012.
DOI : 10.1016/j.jconrel.2011.11.031

URL : http://europepmc.org/articles/pmc3878823?pdf=render