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Detecting and Interpreting Heterogeneity and Publication Bias in Image-Based Meta-Analyses
Abstract : With the increase of data sharing, meta-analyses are becoming increasingly important in the neuroimaging community. They provide a quantitative summary of published results and heightened confidence due to higher statistical power. The gold standard approach to combine results from neuroimaging studies is an Image-Based Meta-Analysis (IBMA) [1] in which group-level maps from different studies are combined.
Recently, we have introduced the IBMA toolbox, an extension for SPM that provides methods for combining image maps from multiple studies [2]. However, the current toolbox lacks diagnostic tools used to assess critical assumptions of meta-analysis, in particular whether there is inter-study variation requiring random-effects IBMA, and whether publication bias is present. Here, we present two new tools added to the IBMA toolbox to detect heterogeneity and to assess evidence of publication bias.
https://www.hal.inserm.fr/inserm-01933023
Contributor : Camille Maumet <>
Submitted on : Thursday, November 29, 2018 - 5:22:23 PM
Last modification on : Tuesday, February 25, 2020 - 8:08:11 AM
Contributor : Camille Maumet <>
Submitted on : Thursday, November 29, 2018 - 5:22:23 PM
Last modification on : Tuesday, February 25, 2020 - 8:08:11 AM
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MaullinSapey_OHBM2018.pdf
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