T. Aoyama and N. Chua, A glucocorticoid-mediated transcriptional induction system in transgenic plants, Plant J, vol.11, pp.605-612, 1997.

F. F. Assaad and E. R. Signer, Somatic and germinal recombination of a direct repeat in Arabidopsis, Genetics, vol.132, pp.553-566, 1992.

S. Balzergue, B. Dubreucq, S. Chauvin, I. Le-clainche, F. Le-boulaire et al., Improved PCRwalking for large-scale isolation of plant T-DNA borders, Biotechniques, vol.30, p.504, 2001.

M. Christian, T. Cermak, E. L. Doyle, C. Schmidt, F. Zhang et al., Targeting DNA double-strand breaks with TAL effector nucleases, Genetics, vol.186, pp.757-761, 2010.

O. Cotsaftis and E. Guiderdoni, Enhancing gene targeting efficiency in higher plants: rice is on the move, Transgenic Res, vol.184, pp.1-14, 2005.

D. 'halluin, K. Vanderstraeten, C. Stals, E. Cornelissen, M. Ruiter et al., Homologous recombination: a basis for targeted genome optimization in crop species such as maize, Plant Biotechnol. J, vol.6, pp.93-102, 2008.

F. Fauser, N. Roth, M. Pacher, G. Ilg, R. Sà-nchez-fernà-ndez et al., planta gene targeting. Proc. Natl Acad. Sci. USA, vol.109, pp.7535-7540, 2012.

W. J. Gong and K. G. Golic, Ends-out, or replacement, gene targeting in Drosophila, Proc. Natl Acad. Sci. USA, vol.100, pp.2556-2561, 2003.

M. Grelon, D. Vezon, G. Gendrot, and G. Pelletier, AtSPO11-1 is necessary for efficient meiotic recombination in plants, EMBO J, vol.20, pp.589-600, 2001.

M. Hanin and J. Paszkowski, Plant genome modification by homologous recombination, Curr. Opin. Plant Biol, vol.6, pp.157-162, 2003.

M. Hanin, S. Volrath, A. Bogucki, M. Briker, E. Ward et al., Gene targeting in Arabidopsis, Plant J, vol.28, pp.671-677, 2001.

A. Hoekema, P. R. Hirsch, P. J. Hooykaas, and R. A. Schilperoort, A binary plant vector strategy based on separation of vir-and T-region of the Agrobacterium tumefaciens Ti-plasmid, Nature, vol.303, pp.179-180, 1983.

J. Huang, W. Zhou, A. M. Watson, Y. N. Jan, and Y. Hong, Efficient ends-out gene targeting in Drosophila, Genetics, vol.180, pp.703-707, 2008.

Y. Ishida, H. Saito, S. Ohta, Y. Hiei, T. Komari et al., High efficiency transformation of maize (Zea mays L.) mediated by Agrobacterium tumefaciens, Nat. Biotechnol, vol.14, pp.745-750, 1996.

A. Jacquier and B. Dujon, An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene, Cell, vol.41, pp.383-394, 1985.

K. K. Khanna, M. F. Lavin, S. P. Jackson, and T. D. Mulhern, ATM, a central controller of cellular responses to DNA damage, Cell Death Differ, vol.8, pp.1052-1065, 2001.

T. Komari, Y. Hiei, Y. Saito, N. Murai, and T. Kumashiro, Vectors carrying two separate T-DNAs for co-transformation of higher plants mediated by Agrobacterium tumefaciens and segregation of transformants free from selection markers, Plant J, vol.10, pp.165-174, 1996.

P. J. Krysan, J. C. Young, and M. R. Sussman, T-DNA as an insertional mutagen in Arabidopsis, Plant Cell, vol.11, pp.2283-2290, 1999.

C. Lu, V. Vasil, and I. K. Vasil, Improved efficiency of somatic embryogenesis and plant regeneration in tissue cultures of maize (Zea mays L.), Theor. Appl. Genet, vol.66, pp.285-289, 1983.

A. J. Matzke and M. A. Matzke, Position effects and epigenetic silencing of plant transgenes, Curr. Opin. Plant Biol, vol.1, pp.142-148, 1998.

D. Mcelroy, A. D. Blowers, B. Jenes, and R. Wu, Construction of expression vectors based on the rice actin 1 (Act1) 5? region for use in monocot transformation, Mol. Gen. Genet, vol.231, pp.150-160, 1991.

J. Paszkowski, M. Baur, A. Bogucki, and I. Potrykus, Gene targeting in plants, EMBO J, vol.7, pp.4021-4026, 1988.

. De, S. Pater, L. W. Neuteboom, J. E. Pinas, P. J. Hooykaas et al., ZFN-induced mutagenesis and gene-targeting in Arabidopsis through Agrobacterium-mediated floral dip transformation, Plant Biotechnol. J, vol.7, pp.821-835, 2009.

A. Peterhans, H. Schlupmann, C. Basse, and J. , Intrachromosomal recombination in plants, EMBO J, vol.9, pp.3437-3445, 1990.

H. Puchta, Double-strand break-induced recombination between ectopic homologous sequences in somatic plant cells, Genetics, vol.152, pp.1173-1181, 1999.

H. Puchta, B. Dujon, and B. Hohn, Homologous recombination in plant cells is enhanced by in vivo induction of double strand breaks into DNA by a site-specific endonuclease, Nucleic Acids Res, vol.21, pp.5034-5040, 1993.

H. Puchta, B. Dujon, and B. Hohn, Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination, Proc. Natl Acad. Sci. USA, vol.93, pp.5055-5060, 1996.

Y. S. Rong, Gene targeting by homologous recombination: a powerful addition to the genetic arsenal for Drosophila geneticists, Biochem. Biophys. Res. Commun, vol.297, pp.1-5, 2002.

C. Sallaud, D. Meynard, J. Van-boxtel, C. Gay, M. Bes et al., Highly efficient production and characterization of T-DNA plants for rice, Oryza sativa L.) functional genomics. Theor. Appl. Genet, vol.106, pp.1396-1408, 2003.

J. Sambrook and D. W. Russell, The condensed protocols from Molecular cloning: a laboratory manual, 2006.

P. H. Schü-nmann, D. J. Llewellyn, B. Surin, P. Boevink, R. C. Feyter et al., A suite of novel promoters and terminators for plant biotechnology, Funct. Plant Biol, vol.30, pp.443-452, 2003.

V. K. Shukla, Y. Doyon, J. C. Miller, R. C. Dekelver, E. A. Moehle et al., Precise genome modification in the crop species Zea mays using zinc-finger nucleases, Nature, vol.459, pp.437-441, 2009.

J. W. Szostak, T. L. Orr-weaver, R. J. Rothstein, and F. W. Stahl, The double-strand-break repair model for recombination, Cell, vol.33, pp.25-35, 1983.

N. Tuteja, P. Ahmad, B. B. Panda, and R. Tuteja, Genotoxic stress in plants: shedding light on DNA damage, repair and DNA repair helicases, Mutation Res, vol.681, pp.134-149, 2009.

T. Tzfira and C. White, Towards targeted mutagenesis and gene replacement in plants, Trends Biotechnol, vol.23, pp.567-569, 2005.
URL : https://hal.archives-ouvertes.fr/inserm-00595923

T. Tzfira, J. Li, B. I. Lacroix, and V. Citovsky, Agrobacterium T-DNA integration: molecules and models, Trends Genet, vol.20, pp.375-383, 2004.

T. Tzfira, D. Weinthal, I. Marton, V. Zeevi, A. Zuker et al., Genome modifications in plant cells by custom-made restriction enzymes, Plant Biotechnol. J, vol.10, pp.373-389, 2012.

B. Verdaguer, A. De-kochko, C. I. Fux, R. N. Beachy, and C. Fauquet, Functional organization of the cassava vein mosaic virus (CsVMV) promoter, Plant Mol. Biol, vol.37, pp.1055-1067, 1998.

A. C. Vergunst, L. E. Jansen, and P. J. Hooykaas, Site-specific integration of Agrobacterium T-DNA in Arabidopsis thaliana mediated by Cre recombinase, Nucleic Acids Res, vol.26, pp.2729-2734, 1998.

S. Wehrkamp-richter, F. Degroote, J. B. Laffaire, W. Paul, P. Perez et al., Characterisation of a new reporter system allowing high throughput in planta screening for recombination events before and after controlled DNA double strand break induction, Plant Physiol. Biochem, vol.47, pp.248-255, 2009.

J. White, S. Y. Chang, and M. J. Bibb, A cassette containing the bar gene of Streptomyces hygroscopicus: a selectable marker for plant transformation, Nucleic Acids Res, vol.18, p.1062, 1990.

M. Yang, V. Djukanovic, J. Stagg, B. Lenderts, D. Bidney et al., Targeted mutagenesis in the progeny of maize transgenic plants, Plant Mol. Biol, vol.70, pp.669-679, 2009.