Mammalian telomeres end in a large duplex loop, Cell, vol.97, pp.503-514, 1999. ,
Telomere looping in P. sativum (common garden pea), Plant J, vol.36, pp.271-279, 2003. ,
) t-loops at trypanosome telomeres, EMBO J, vol.20, pp.579-588, 2001. ,
How shelterin protects mammalian telomeres, Annu. Rev. Genet, vol.42, pp.301-334, 2008. ,
How telomeres solve the end-protection problem, Science, vol.326, pp.948-952, 2009. ,
How telomeres are replicated, Nat. Rev. Mol. Cell Biol, vol.8, pp.825-838, 2007. ,
The role of double-strand break repair pathways at functional and dysfunctional telomeres, Cold Spring Harb. Perspect. Biol, vol.6, p.16576, 2014. ,
BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function, Mol. Cell. Biol, vol.24, pp.6701-6709, 2004. ,
Semi-conservative DNA replication through telomeres requires Taz1, Nature, vol.440, pp.824-828, 2006. ,
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication, Cell, vol.138, pp.90-103, 2009. ,
Quantitative visualization of DNA G-quadruplex structures in human cells, Nat. Chem, vol.5, pp.182-186, 2013. ,
Genomes and G-quadruplexes: for better or for worse, J. Mol. Biol, vol.425, pp.4782-4789, 2013. ,
G-quadruplex structures: in vivo evidence and function, Trends Cell Biol, vol.19, pp.414-422, 2009. ,
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity, Cell, vol.149, pp.795-806, 2012. ,
G-quadruplexes and their regulatory roles in biology, Nucleic Acids Res, vol.43, pp.8627-8637, 2015. ,
A conserved G4 DNA binding domain in RecQ family helicases, J. Mol. Biol, vol.358, pp.1071-1080, 2006. ,
Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process, Carcinogenesis, vol.24, pp.791-802, 2003. ,
The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo, PLoS Genet, vol.5, p.1000475, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-02109281
Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates, Nat. Struct. Mol. Biol, vol.15, pp.598-604, 2008. ,
Telomeric G-quadruplexes are a substrate and site of localization for human telomerase, Nat. Commun, vol.6, p.7643, 2015. ,
The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening, EMBO J, vol.32, pp.2861-2871, 2013. ,
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends, Science, vol.318, pp.798-801, 2007. ,
Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence, Nucleic Acids Res, vol.40, pp.6649-6659, 2012. ,
Ribonuclease H: the enzymes in eukaryotes, FEBS J, vol.276, pp.1494-1505, 2009. ,
Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence, Nat. Struct. Mol. Biol, vol.20, pp.1199-1205, 2013. ,
RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells, Nat. Commun, vol.5, p.5220, 2014. ,
Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase, Proc. Natl. Acad. Sci. U.S.A, vol.111, pp.3377-3382, 2014. ,
Telomere elongation chooses TERRA ALTernatives, RNA Biol, vol.12, pp.938-941, 2015. ,
Telomere recombination and alternative telomere lengthening mechanisms, Front. Biosci, vol.18, pp.1-20, 2013. ,
Alternative lengthening of telomeres: models, mechanisms and implications, Nat. Rev. Genet, vol.11, pp.319-330, 2010. ,
Molecular mechanisms of activity and derepression of alternative lengthening of telomeres, Nat. Struct. Mol. Biol, vol.22, pp.875-880, 2015. ,
How homologous recombination maintains telomere integrity, Chromosoma, vol.124, pp.119-130, 2015. ,
RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase, Genetics, vol.152, pp.143-152, 1999. ,
Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA, Proc. Natl. Acad. Sci. U.S.A, vol.96, pp.14813-14818, 1999. ,
Living with genome instability: plant responses to telomere dysfunction, Science, vol.291, pp.1797-1800, 2001. ,
, Nucleic Acids Research, vol.46, issue.5, p.2445, 2018.
Role of alternative telomere lengthening unmasked in telomerase knock-out mutant plants, Plant Mol. Biol, vol.66, pp.637-646, 2008. ,
ATM regulates the length of individual telomere tracts in Arabidopsis, Proc. Natl. Acad. Sci. U.S.A, vol.104, pp.18145-18150, 2007. ,
Meiotic recombination in Arabidopsis is catalysed by DMC1, with RAD51 playing a supporting role, PLoS Genet, vol.9, p.1003787, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-01907382
Green fluorescent protein fused to the C terminus of RAD51 specifically interferes with secondary DNA binding by the RAD51-ssDNA complex, Genes Genet. Syst, vol.89, pp.169-179, 2014. ,
Arabidopsis thaliana RNase H2 deficiency counteracts the needs for the WEE1 checkpoint kinase but triggers genome instability, Plant Cell, vol.26, pp.3680-3692, 2014. ,
URL : https://hal.archives-ouvertes.fr/inserm-01907361
The Arabidopsis thaliana homolog of the helicase RTEL1 plays multiple roles in preserving genome stability, Plant Cell, vol.26, pp.4889-4902, 2014. ,
Xrcc1-dependent and Ku-dependent DNA double-strand break repair kinetics in Arabidopsis plants, Plant J, vol.64, pp.280-290, 2010. ,
URL : https://hal.archives-ouvertes.fr/inserm-00595784
The recombinases DMC1 and RAD51 are functionally and spatially separated during meiosis in Arabidopsis, Plant Cell, vol.24, pp.2058-2070, 2012. ,
Distinct roles of the ATR kinase and the Mre11-Rad50-Nbs1 complex in the maintenance of chromosomal stability in Arabidopsis, Plant Cell, vol.22, pp.3020-3033, 2010. ,
URL : https://hal.archives-ouvertes.fr/inserm-00595794
Chromosome painting in plants, Methods Cell Sci, vol.23, pp.57-69, 2001. ,
DOI : 10.1007/978-94-010-0330-8_7
Two roles for Rad50 in telomere maintenance, EMBO J, vol.25, pp.4577-4585, 2006. ,
URL : https://hal.archives-ouvertes.fr/inserm-00595800
RAD50 function is essential for telomere maintenance in Arabidopsis, Proc. Natl. Acad. Sci. U.S.A, vol.98, pp.1711-1716, 2001. ,
DOI : 10.1073/pnas.98.4.1711
URL : https://hal.archives-ouvertes.fr/inserm-00595834
Molecular analysis of telomere fusions in Arabidopsis: multiple pathways for chromosome end-joining, EMBO J, vol.23, pp.2304-2313, 2004. ,
The Arabidopsis homologue of Xrcc3 plays an essential role in meiosis, EMBO J, vol.23, pp.439-449, 2004. ,
URL : https://hal.archives-ouvertes.fr/inserm-00595813
ERCC1/XPF protects short telomeres from homologous recombination in Arabidopsis thaliana, PLoS Genet, vol.5, p.1000380, 2009. ,
DOI : 10.1371/journal.pgen.1000380
URL : https://hal.archives-ouvertes.fr/inserm-00595799
Transcription as a threat to genome integrity, Annu. Rev. Biochem, vol.85, pp.291-317, 2016. ,
DOI : 10.1146/annurev-biochem-060815-014908
URL : https://digital.csic.es/bitstream/10261/165338/1/accesoRestringido.pdf
Hypomethylating drugs efficiently decrease cytosine methylation in telomeric DNA and activate telomerase without affecting telomere lengths in tobacco cells, Plant Mol. Biol, vol.77, pp.371-380, 2011. ,
) siRNA-mediated methylation of Arabidopsis telomeres, PLoS Genet, vol.6, p.1000986, 2010. ,
TERRA and the state of the telomere, Nat. Struct. Mol. Biol, vol.22, pp.853-858, 2015. ,
, RTEL1 maintains genomic stability by suppressing homologous recombination, vol.135, pp.261-271, 2008.
DOI : 10.1016/j.cell.2008.08.016
URL : https://doi.org/10.1016/j.cell.2008.08.016
The DNA damage response at eroded telomeres and tethering to the nuclear pore complex, Nat. Cell Biol, vol.11, pp.980-987, 2009. ,
Early telomerase inactivation accelerates aging independently of telomere length, Cell, vol.160, pp.928-939, 2015. ,
Early loss of telomerase action in yeast creates a dependence on the DNA damage response adaptor proteins, Mol. Cell. Biol, vol.36, pp.1908-1919, 2016. ,
Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages, Nat. Commun, vol.6, p.7680, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01308895
BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping, Nat. Struct. Mol. Biol, vol.17, pp.1461-1469, 2010. ,
Alternative lengthening of telomeres in normal mammalian somatic cells, Genes Dev, vol.27, pp.18-23, 2013. ,
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA, Cell, vol.91, pp.25-34, 1997. ,
DOI : 10.1016/s0092-8674(01)80006-4
URL : https://doi.org/10.1016/s0092-8674(01)80006-4
Alternative lengthening of telomeres mediated by mitotic DNA synthesis engages break-induced replication processes, Mol. Cell. Biol, vol.37, pp.226-243, 2017. ,
Alternative lengthening of human telomeres is a conservative DNA replication process with features of break-induced replication, EMBO Rep, vol.17, pp.1731-1737, 2016. ,
Interchromosomal homology searches drive directional ALT telomere movement and synapsis, Cell, vol.159, pp.108-121, 2014. ,
DOI : 10.1016/j.cell.2014.08.030
URL : https://doi.org/10.1016/j.cell.2014.08.030
Break-induced telomere synthesis underlies alternative telomere maintenance, Nature, vol.539, pp.54-58, 2016. ,
DOI : 10.1038/nature20099
URL : http://europepmc.org/articles/pmc5384111?pdf=render
Extrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase delta-mediated telomere-telomere recombination in Saccharomyces cerevisiae, Eukaryot. Cell, vol.4, pp.327-336, 2005. ,
DOI : 10.1128/ec.4.2.327-336.2005
URL : http://europepmc.org/articles/pmc549320?pdf=render
Telomerase-and capping-independent yeast survivors with alternate telomere states, Nat. Cell Biol, vol.8, pp.741-747, 2006. ,
Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination, Nucleic Acids Res, vol.38, pp.182-189, 2010. ,
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity, Nat. Biotechnol, vol.27, pp.1181-1185, 2009. ,
Ku suppresses formation of telomeric circles and alternative telomere lengthening in Arabidopsis, Mol. Cell, vol.27, pp.163-169, 2007. ,
Telomere maintenance is dependent on activities required for end repair of double-strand breaks, Curr. Biol, vol.8, pp.657-660, 1998. ,
Break-induced replication and recombinational telomere elongation in yeast, Annu. Rev. Biochem, vol.75, pp.111-135, 2006. ,
Break induced replication in eukaryotes: mechanisms, functions, and consequences, Crit. Rev. Biochem. Mol. Biol, vol.52, pp.395-413, 2017. ,
BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres, EMBO J, vol.36, pp.2907-2919, 2017. ,