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Translational molecular imaging in exocrine pancreatic cancer

Bart Cornelissen 1, * James Knight 1 Somnath Mukherjee 1 Laura Evangelista 2 Catarina Xavier 3 Federico Caobelli 4 Silvana del Vecchio 5 Latifa Rbah-Vidal 6 Jacques Barbet 6 Marion de Jong 7 Fijs van Leeuwen 8
* Corresponding author
1 CRUK/MRC - Department of Oncology [Oxford, UK]
2 Istituto Oncologico Veneto I.R.C.C.S. [Padova, Italy]
3 VUB - Vrije Universiteit Brussel
4 Department of Radiology [Basel, Switzerland]
5 Università degli studi di Napoli Federico II
6 CRCINA-ÉQUIPE 13 - Nuclear Oncology
CRCINA - Centre de Recherche en Cancérologie et Immunologie Nantes-Angers
7 Department of Radiology & Nuclear Medicine [Rotterdam, The Netherlands]
8 Interventional Molecular Imaging Laboratory [Leiden, the Netherlands]
Abstract : Effective treatment for pancreatic cancer remains challenging, particularly the treatment of pancreatic ductal adenocarcinoma (PDAC), which makes up more than 95% of all pancreatic cancers. Late diagnosis and failure of chemotherapy and radiotherapy are all too common, and many patients die soon after diagnosis. Here, we make the case for the increased use of molecular imaging in PDAC preclinical research and in patient management.
Keywords : Preclinical developments SPECT Molecular imaging PET Pancreatic ductal adenocarcinoma
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https://www.hal.inserm.fr/inserm-01885212
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Bart Cornelissen, James Knight, Somnath Mukherjee, Laura Evangelista, Catarina Xavier, et al.. Translational molecular imaging in exocrine pancreatic cancer. European Journal of Nuclear Medicine and Molecular Imaging, Springer Verlag (Germany), 2018, Epub ahead of print. ⟨10.1007/s00259-018-4146-5⟩. ⟨inserm-01885212⟩

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