Systemic inflammation and disease progression in Alzheimer disease, Neurology, vol.73, pp.768-774, 2009. ,
Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research, Alzheimers Res Ther, vol.7, p.33, 2015. ,
Microglial priming in neurodegenerative disease, Nat Rev Neurol, vol.10, pp.217-224, 2014. ,
Neutrophils at work, Nat Immunol, vol.15, pp.602-611, 2014. ,
The role of neutrophils in autoimmune diseases, Immunol Lett, vol.143, pp.9-19, 2012. ,
Neutrophils and immunity: challenges and opportunities, Nat Rev Immunol, vol.6, pp.173-182, 2006. ,
Involvement of ROS in BBB dysfunction, Free Radic Res, vol.43, pp.348-364, 2009. ,
Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin, Nat Med, vol.21, pp.880-886, 2015. ,
Proinflammatory cytokines, sickness behavior, and Alzheimer disease, Neurology, vol.77, pp.212-218, 2011. ,
Alterations in immune functions during normal aging and Alzheimer's disease, Psychiatry Res, vol.85, pp.71-80, 1999. ,
Oxidative stress level in circulating neutrophils is linked to neurodegenerative diseases, J Clin Immunol, vol.24, pp.683-692, 2004. ,
Neutrophils CD11b and fibroblasts PGE(2) are elevated in Alzheimer's disease, Neurobiol Aging, vol.23, pp.523-530, 2002. ,
Increased chemiluminescence response of neutrophils from the peripheral blood of patients with senile dementia of the Alzheimer's type, J Neuroimmunol, vol.51, pp.21-26, 1994. ,
Phagocytic activity and state of bactericidal systems in polymorphonuclear leukocytes from patients with Alzheimer's disease, Bull Exp Biol Med, vol.136, pp.355-3557, 2003. ,
Oxidative metabolism and release of myeloperoxidase from polymorphonuclear leukocytes obtained from blood sedimentation in a FicollHypaque gradient, Cell Biochem Funct, vol.18, pp.127-132, 2000. ,
Alteration of polymorphonuclear neutrophil surface receptor expression and migratory activity after isolation: comparison of whole blood and isolated PMN preparations from normal and postfracture trauma patients, J Trauma, vol.60, pp.844-850, 2006. ,
Amnestic syndrome of the medial temporal type identifies prodromal AD: a longitudinal study, Neurology, vol.69, pp.1859-1867, 2007. ,
URL : https://hal.archives-ouvertes.fr/inserm-00169640
Revising the definition of Alzheimer's disease: a new lexicon, Lancet Neurol, vol.9, pp.1118-1127, 2010. ,
Similar amyloid-beta burden in posterior cortical atrophy and Alzheimer's disease, Brain, vol.134, issue.7, pp.2036-2043, 2011. ,
Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging, Brain, vol.139, pp.1252-1264, 2016. ,
DOI : 10.1093/brain/aww017
URL : https://academic.oup.com/brain/article-pdf/139/4/1252/17349144/aww017.pdf
Use of CSF biomarkers in the diagnosis of Alzheimer's disease in clinical practice, Rev Neurol, vol.167, pp.474-484, 2011. ,
Reduced Oxidative Burst by Primed Neutrophils in the Elderly Individuals Is Associated With Increased Levels of the CD16bright/CD62Ldim Immunosuppressive Subset, J Gerontol A Biol Sci Med Sci, vol.72, pp.163-172, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01545496
Neutrophils in antiretroviral therapy-controlled HIV demonstrate hyperactivation associated with a specific IL-17/IL-22 environment, J Allergy Clin Immunol, vol.134, pp.1142-1152, 2014. ,
The effect of HMGB1, a damage-associated molecular pattern molecule, on polymorphonuclear neutrophil migration depends on its concentration, J Innate Immun, vol.4, pp.41-58, 2012. ,
Neutrophil extracellular traps downregulate lipopolysaccharide-induced activation of monocyte-derived dendritic cells, J Immunol, vol.193, pp.5689-5698, 2014. ,
DOI : 10.4049/jimmunol.1400586
URL : http://www.jimmunol.org/content/jimmunol/193/11/5689.full.pdf
Netting neutrophils in autoimmune small-vessel vasculitis, Nat Med, vol.15, pp.623-625, 2009. ,
DOI : 10.1038/nm.1959
URL : http://europepmc.org/articles/pmc2760083?pdf=render
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad, J Immunol, vol.174, pp.3633-3642, 2005. ,
RNA-seq reveals activation of both common and cytokine-specific pathways following neutrophil priming, PLoS One, vol.8, p.58598, 2013. ,
DOI : 10.1371/journal.pone.0058598
URL : https://doi.org/10.1371/journal.pone.0058598
Ly6C(1) monocyte efferocytosis and cross-presentation of cell-associated antigens, Cell Death Differ, vol.23, pp.997-1003, 2016. ,
DOI : 10.1038/cdd.2016.24
URL : https://www.nature.com/articles/cdd201624.pdf
Profiler-a web server for functional interpretation of gene lists (2016 update), Nucleic Acids Res, vol.44, issue.W1, pp.83-89, 2016. ,
Regulation of production of soluble Fc gamma receptors type III in normal and pathological conditions, Immunol Lett, vol.68, pp.125-134, 1999. ,
Leukocyte migration is regulated by L-selectin endoproteolytic release, Immunity, vol.19, pp.713-724, 2003. ,
DOI : 10.1016/s1074-7613(03)00295-4
URL : https://doi.org/10.1016/s1074-7613(03)00295-4
Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils, J Clin Invest, vol.92, pp.1467-1476, 1993. ,
Neutrophils, from marrow to microbes, Immunity, vol.33, pp.657-670, 2010. ,
DOI : 10.1016/j.immuni.2010.11.011
URL : https://doi.org/10.1016/j.immuni.2010.11.011
Novel cell death program leads to neutrophil extracellular traps, J Cell Biol, vol.176, pp.231-241, 2007. ,
DOI : 10.1084/jem2041oia2
URL : http://europepmc.org/articles/pmc2063942?pdf=render
In tuberculous pleural effusions, activated neutrophils undergo apoptosis and acquire a dendritic cell-like phenotype, J Infect Dis, vol.192, pp.399-409, 2005. ,
Anti-myeloperoxidase antibodies enhance phagocytosis, IL-8 production, and glucose uptake of polymorphonuclear neutrophils rather than antiproteinase 3 antibodies leading to activation-induced cell death of the neutrophils, Clin Rheumatol, vol.26, pp.216-224, 2007. ,
Mechanisms regulating neutrophil survival and cell death, Semin Immunopathol, vol.35, pp.423-437, 2013. ,
Fcgamma receptors exhibit different phagocytosis potential in human neutrophils, Cell Immunol, vol.263, pp.114-121, 2010. ,
Neutrophil ageing is regulated by the microbiome, Nature, vol.525, pp.528-532, 2015. ,
Human suppressive neutrophils CD16bright/CD62Ldim exhibit decreased adhesion, J Leukoc Biol, vol.92, pp.1011-1020, 2012. ,
A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1, J Clin Invest, vol.122, pp.327-336, 2012. ,
Polymorphonuclear Neutrophil Functions are Differentially Altered in Amnestic Mild Cognitive Impairment and Mild Alzheimer's Disease Patients, J Alzheimers Dis, vol.60, pp.23-42, 2017. ,
Increased expression of DC-SIGN1IL-121IL-18 1 and CD831IL-12-IL-18-dendritic cell populations in the colonic mucosa of patients with Crohn's disease, Eur J Immunol, vol.33, pp.143-151, 2003. ,
Global changes in gene expression by human polymorphonuclear leukocytes during receptor-mediated phagocytosis: cell fate is regulated at the level of gene expression, Proc Natl Acad Sci U S A, vol.99, pp.6901-6906, 2002. ,
Transdifferentiation of polymorphonuclear neutrophils: acquisition of CD83 and other functional characteristics of dendritic cells, J Mol Med (Berl), vol.79, pp.464-474, 2001. ,
Gene expression in mature neutrophils: early responses to inflammatory stimuli, J Leukoc Biol, vol.75, pp.358-372, 2004. ,
Up-regulation of the dendritic cell marker CD83 on polymorphonuclear neutrophils (PMN): divergent expression in acute bacterial infections and chronic inflammatory disease, Clin Exp Immunol, vol.130, pp.501-508, 2002. ,
Neutrophils process exogenous bacteria via an alternate class I MHC processing pathway for presentation of peptides to T lymphocytes, J Immunol, vol.167, pp.2538-2546, 2001. ,
Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells, J Exp Med, vol.192, pp.681-694, 2000. ,
Salt-inducible kinases 1 and 3 negatively regulate Toll-like receptor 4-mediated signal, Mol Endocrinol, vol.27, pp.1958-1968, 2013. ,
Cysteine-rich intestinal protein 2 (CRIP2) acts as a repressor of NF-kappaB-mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis, Proc Natl Acad Sci U S A, vol.108, pp.8390-8395, 2011. ,
The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus, Proc Natl Acad Sci U S A, vol.102, pp.303-308, 2005. ,
Role of inositol 1,4,5-triphosphate and p38 mitogen-activated protein kinase in reactive oxygen species generation by granulocytes in a cyclic AMPdependent manner: an age-related phenomenon, Gerontology, vol.53, pp.228-233, 2007. ,
Cytohesin-1 regulates the Arf6-phospholipase D signaling axis in human neutrophils: impact on superoxide anion production and secretion, J Immunol, vol.184, pp.637-649, 2010. ,
Granulocyte macrophage colony-stimulating factor signaling and proteasome inhibition delay neutrophil apoptosis by increasing the stability of Mcl-1, J Biol Chem, vol.279, pp.26915-26921, 2004. ,
DOI : 10.1074/jbc.m313875200
URL : http://www.jbc.org/content/279/26/26915.full.pdf
Proteasome Inhibition Diminishes the Formation of Neutrophil Extracellular Traps and Prevents the Death of Cardiomyocytes in Coculture with Activated Neutrophils during AnoxiaReoxygenation, Pathobiology, vol.82, pp.290-298, 2015. ,
Circadian regulation of human peripheral neutrophils, Brain Behav Immun, vol.57, pp.209-221, 2016. ,
DOI : 10.1016/j.bbi.2016.04.016
Metalloproteinases in biology and pathology of the nervous system, Nat Rev Neurosci, vol.2, pp.502-511, 2001. ,
Oxidative stress and blood-brain barrier dysfunction under particular consideration of matrix metalloproteinases, Antioxid Redox Signal, vol.15, pp.1305-1323, 2011. ,
DOI : 10.1089/ars.2011.3923
Tissue inhibitors of metalloproteinases: evolution, structure and function, Biochim Biophys Acta, vol.1477, pp.267-283, 2000. ,
DOI : 10.1016/s0167-4838(99)00279-4
Systemic immune responses in Alzheimer's disease: in vitro mononuclear cell activation and cytokine production, J Alzheimers Dis, vol.21, pp.181-192, 2010. ,
Priming of polymorphonuclear neutrophils by tumor necrosis factor alpha in whole blood: identification of two polymorphonuclear neutrophil subpopulations in response to formyl-peptides, Blood, vol.82, pp.633-640, 1993. ,
Differential priming effects of proinflammatory cytokines on human neutrophil oxidative burst in response to bacterial Nformyl peptides, Infect Immun, vol.62, pp.2195-2201, 1994. ,
Neutrophil extracellular traps and their role in the development of chronic inflammation and autoimmunity, Autoimmun Rev, vol.14, pp.633-640, 2015. ,
A study on the association between infectious burden and Alzheimer's disease, Eur J Neurol, vol.22, pp.1519-1525, 2015. ,
Adrover AM. Answer to the Letter to the Editor of L. P. Ardigo et al. concerning "Validity and reliability of photographic measures to evaluate waistline asymmetry in idiopathic scoliosis, J Alzheimers Dis, vol.41, pp.301-311, 2014. ,
, Eur Spine J, vol.25, pp.3019-3020, 2016.
Blood-brain barrier impairment in dementia: current and future in vivo assessments, Neurosci Biobehav Rev, vol.49, pp.71-81, 2015. ,
Blood-brain barrier impairment in Alzheimer disease: stability and functional significance, Neurology, vol.68, pp.1809-1814, 2007. ,
Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo, PLoS One, vol.8, p.64034, 2013. ,
Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia, Am J Physiol Heart Circ Physiol, vol.289, pp.558-568, 2005. ,
NOX enzymes and the biology of reactive oxygen, Nat Rev Immunol, vol.4, pp.181-189, 2004. ,
MMPs in the central nervous system: where the good guys go bad, Semin Cell Dev Biol, vol.19, pp.42-51, 2008. ,
Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction, J Neurochem, vol.101, pp.566-576, 2007. ,
Aged neutrophils contribute to the first line of defense in the acute inflammatory response, Blood, vol.128, pp.2327-2337, 2016. ,
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease, J Neurosci, vol.25, pp.8843-8853, 2005. ,
GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP, Brain, vol.138, pp.3076-3088, 2015. ,
An early and late peak in microglial activation in Alzheimer's disease trajectory, Brain, vol.140, pp.792-803, 2017. ,
High interleukin-6 plasma levels are associated with functional impairment in older patients with vascular dementia, Int J Geriatr Psychiatry, vol.22, pp.305-311, 2007. ,
Altered plasma cytokine levels in Alzheimer's disease: correlation with the disease progression, Immunol Lett, vol.114, pp.46-51, 2007. ,
Increased serum levels of interleukin-18,-23 and-17 in Chinese patients with Alzheimer's disease, Dement Geriatr Cogn Disord, vol.38, pp.321-329, 2014. ,
The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease, J Alzheimers Dis, vol.43, pp.725-738, 2015. ,
Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly, Neurobiol Aging, vol.49, pp.60-68, 2017. ,
Deregulation of purine metabolism in Alzheimer's disease, Neurobiol Aging, vol.36, pp.68-80, 2015. ,