Age-related macular degeneration, Lancet, vol.431379, issue.9827, pp.1728-1766, 2012. ,
Global prevalence of age-related macular degeneration and 433 ,
, disease burden projection for 2020 and 2040: a systematic review and meta-analysis, Lancet, vol.434
, Glob Health, vol.2, issue.2, pp.106-122, 2014.
Ranibizumab for neovascular age-related 436 ,
, macular degeneration, N Engl J Med, vol.355, issue.4, pp.1419-1450, 2006.
Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration, Ophthalmology, vol.119, issue.12, pp.2537-2585, 2012.,
DOI : 10.1016/j.ophtha.2012.09.006
High Variation of Intravitreal Injection Rates 440 ,
, and Medicare Anti-Vascular Endothelial Growth Factor Payments per Injection in the United 441
, States. Ophthalmology, vol.123, issue.6, pp.1257-62, 2016.
Nature and nurture- genes and environment- predict onset and progression of macular degeneration, Progress in Retinal and Eye Research, vol.40, issue.7, pp.1-15, 2014.,
DOI : 10.1016/j.preteyeres.2013.12.004
Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration, JAMA: The Journal of the American Medical Association, vol.272, issue.18, pp.1413-1433, 1994.,
DOI : 10.1001/jama.1994.03520180037032
Lutein and Zeaxanthin in the Diet and Serum and Their Relation to Age-related Maculopathy in the Third National Health and Nutrition Examination Survey, American Journal of Epidemiology, vol.153, issue.5, pp.424-456, 2001.,
DOI : 10.1001/archopht.1995.01100060069034
Plasma lutein and zeaxanthin and other 451 carotenoids as modifiable risk factors for age-related maculopathy and cataract, p.452 ,
, Study. Invest Ophthalmol Vis Sci, vol.47, issue.6, pp.2329-2364, 2006.
Prospective study of lutein/zeaxanthin intake and risk of age-related macular degeneration, The American Journal of Clinical Nutrition, vol.84, issue.6, pp.1837-1880, 2008.,
DOI : 10.1093/ajcn/84.5.1107
Lutein and zeaxanthin intake and the risk of age-related 456 ,
macular degeneration: a systematic review and meta-analysis Dietary intake of antioxidants and risk 458 of age-related macular degeneration, Br J Nutr JAMA, vol.107294, issue.459, pp.350-359, 2005. ,
Progression of age-related macular degeneration: 460 association with dietary fat, transunsaturated fat, nuts, and fish intake, Arch Ophthalmol, vol.461121, issue.462, pp.1728-1765, 2003. ,
Cigarette smoking, fish consumption, omega-3 fatty 463 acid intake, and associations with age-related macular degeneration: the US Twin Study of Age, p.464 ,
, Related Macular Degeneration, Arch Ophthalmol, vol.124, issue.465, pp.995-1001, 2006.
Circulating Omega-3 Fatty Acids and Neovascular Age-Related Macular Degeneration, Investigative Opthalmology & Visual Science, vol.55, issue.3, pp.2010-2019, 2014.,
DOI : 10.1167/iovs.14-13916
Oily fish consumption, dietary docosahexaenoic acid and eicosapentaenoic acid intakes, and associations with neovascular age-related macular degeneration, The American Journal of Clinical Nutrition, vol.83, issue.2, pp.398-406, 2008.,
DOI : 10.1093/ajcn/83.6.1526S
Dietary omega-3 fatty acid and fish intake in the 471 primary prevention of age-related macular degeneration: a systematic review and meta-analysis, p.472 ,
, Arch Ophthalmol, vol.126, issue.473, pp.826-859, 2008.
Mediterranean diet pyramid: a cultural model for healthy eating, The American Journal of Clinical Nutrition, vol.61, issue.6, pp.1402-1408, 1995.,
DOI : 10.1093/ajcn/61.6.1402S
Diet and overall survival in elderly 476 people Primary prevention of cardiovascular disease 478 with a Mediterranean diet, BMJ N Engl J Med, vol.311368121, issue.508, pp.1457-601279, 1995. ,
The Wisconsin age-related maculopathy grading 509 system An international classification and grading 511 system for age-related maculopathy and age-related macular degeneration. The International 512 ARM Epidemiological Study Group Dietary assessment in the 514 elderly: validation of a semiquantitative food frequency questionnaire, Ophthalmology Surv Ophthalmol Eur J Clin Nutr, vol.983952, issue.516, pp.1128-34367, 1991. ,
, , p.517
, French elderly community dwellers and association with socio-demographic characteristics: data 518 from the Bordeaux sample of the Three-City Study, Br J Nutr, vol.98, issue.519, pp.1046-57, 2007.
Dietary patterns derived by hybrid clustering 520 method in older people: association with cognition, mood, and self-rated health Adherence to a Mediterranean 523 diet and survival in a Greek population Determinants of disease 525 and disability in the elderly: the Rotterdam Elderly Study, J Am Diet Assoc N Engl J Med Eur J Epidemiol, vol.5211083487, issue.526, pp.1461-712599, 1991. ,
Reducing the genetic risk of age-related 527 ,
, macular degeneration with dietary antioxidants, zinc, and omega-3 fatty acids: the Rotterdam 528 study, Arch Ophthalmol, vol.129, issue.529, pp.758-66, 2011.
Genome-wide association study identifies variants at 530 Secondary 1823 (41.2) 529 (29.3) 130 (23.7) 56 (19.8) Higher 403, pp.128-135 ,
, Body mass index, mean (SD), kg