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, Supporting information Additional Supporting Information may be found online in the supporting information tab for this article
, Radiograph grading score for bone defect healing as determined by two blinded, independent assessors. Grades for (i) defect tissue/material structure and (ii) bridging were combined to give a final combined radiograph score
, Semi-quantitation of bone formation was performed by taking (A) the total defect area and applying thresholding parameters to (B) create a mask of new callus using Adobe Photoshop CS5