, of SR proteins by AKT, Nat Struct Mol Biol, vol.12, pp.1037-1044

M. Blaustein, L. Quadrana, G. Risso, M. Mde, L. Pelisch et al., , 2009.

, ASF regulates proteomic diversity by affecting the balance between translation initiation mechanisms, SF2, pp.826-833

E. Buratti and F. Baralle, Influence of RNA Secondary Structure on the Pre-mRNA Splicing Process, Molecular and Cellular Biology, vol.24, issue.24, pp.10505-10514, 2004.
DOI : 10.1128/MCB.24.24.10505-10514.2004

H. Chang, J. Chi, S. Dudoit, C. Bondre, M. Van-de-rijn et al., Diversity, topographic differentiation, and positional memory in human fibroblasts, Proceedings of the National Academy of Sciences, vol.122, issue.10, pp.12877-12882, 2002.
DOI : 10.1126/science.287.5457.1427

URL : http://www.pnas.org/content/99/20/12877.full.pdf

M. Chen and J. Manley, Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches, Nature Reviews Molecular Cell Biology, vol.78, issue.11, pp.741-754, 2009.
DOI : 10.1128/MCB.12.7.3204

P. Cramer, J. Caceres, D. Cazalla, S. Kadener, A. Muro et al., Coupling of Transcription with Alternative Splicing, Molecular Cell, vol.4, issue.2, pp.251-258, 1999.
DOI : 10.1016/S1097-2765(00)80372-X

URL : https://doi.org/10.1016/s1097-2765(00)80372-x

P. Cramer, C. Pesce, F. Baralle, and A. Kornblihtt, Functional association between promoter structure and transcript alternative splicing, Proceedings of the National Academy of Sciences, vol.241, issue.4867, pp.11456-11460, 1997.
DOI : 10.1126/science.3043662

URL : http://www.pnas.org/content/94/21/11456.full.pdf

C. Damsky, C. Librach, K. Lim, M. Fitzgerald, M. Mcmaster et al., Integrin switching regulates normal trophoblast invasion, Development, vol.120, pp.3657-3666, 1994.

M. De-la-mata, C. Alonso, S. Kadener, J. Fededa, M. Blaustein et al., A Slow RNA Polymerase II Affects Alternative Splicing In Vivo, Molecular Cell, vol.12, issue.2, pp.525-532, 2003.
DOI : 10.1016/j.molcel.2003.08.001

M. De-la-mata, C. Lafaille, and A. Kornblihtt, First come, first served revisited: Factors affecting the same alternative splicing event have different effects on the relative rates of intron removal, RNA, vol.16, issue.5, pp.904-912, 2010.
DOI : 10.1261/rna.1993510

P. Fafet, C. Rebouissou, T. Maudelonde, and M. Vignais, Opposite Effects of Transforming Growth Factor-?? Activation and Rho-Associated Kinase Inhibition on Human Trophoblast Migration in a Reconstituted Placental-Endometrial Coculture System, Endocrinology, vol.149, issue.9, pp.4475-4485, 2008.
DOI : 10.1210/en.2008-0253

URL : https://hal.archives-ouvertes.fr/inserm-01855902

R. Feinberg, H. Kliman, and C. Lockwood, Is oncofetal fibronectin a trophoblast glue for human implantation?, Am J Pathol, vol.138, pp.537-543, 1991.

C. Ffrench-constant, L. Van-de-water, H. Dvorak, and R. Hynes, Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat, The Journal of Cell Biology, vol.109, issue.2, pp.903-914, 1989.
DOI : 10.1083/jcb.109.2.903

C. Frantz, K. Stewart, and V. Weaver, The extracellular matrix at a glance, Journal of Cell Science, vol.123, issue.24, pp.4195-4200, 2010.
DOI : 10.1242/jcs.023820

P. Friedl and A. S. , Cancer Invasion and the Microenvironment: Plasticity and Reciprocity, Cell, vol.147, issue.5, pp.992-1009, 2011.
DOI : 10.1016/j.cell.2011.11.016

URL : https://doi.org/10.1016/j.cell.2011.11.016

E. George, E. Georges-labouesse, R. Patel-king, H. Rayburn, and R. Hynes, Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin, Development, vol.119, pp.1079-1091, 1993.

J. Guan, J. Trevithick, and R. Hynes, Retroviral expression of alternatively spliced forms of rat fibronectin, The Journal of Cell Biology, vol.110, issue.3, pp.833-847, 1990.
DOI : 10.1083/jcb.110.3.833

URL : http://jcb.rupress.org/content/110/3/833.full.pdf

L. Harris, C. Jones, and J. Aplin, Adhesion Molecules in Human Trophoblast ??? A Review. II. Extravillous Trophoblast, Placenta, vol.30, issue.4, pp.299-304, 2009.
DOI : 10.1016/j.placenta.2008.12.003

B. Hartmann and J. Valcarcel, Decrypting the genome's alternative messages, Current Opinion in Cell Biology, vol.21, issue.3, pp.377-386, 2009.
DOI : 10.1016/j.ceb.2009.02.006

J. Heino, The collagen family members as cell adhesion proteins, BioEssays, vol.15, issue.10, pp.1001-1010, 2007.
DOI : 10.1093/embo-reports/kve094

J. Johnson, J. Castle, P. Garrett-engele, Z. Kan, P. Loerch et al., Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays, Science, vol.302, issue.5653, pp.2141-2144, 2003.
DOI : 10.1126/science.1090100

J. Joyce and J. Pollard, Microenvironmental regulation of metastasis, Nature Reviews Cancer, vol.19, issue.4, pp.239-252, 2009.
DOI : 10.1053/sonc.2002.37263

S. Kadener, P. Cramer, G. Nogues, D. Cazalla, M. De-la-mata et al., Antagonistic effects of T-Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing, The EMBO Journal, vol.20, issue.20, pp.5759-5768, 2001.
DOI : 10.1093/emboj/20.20.5759

S. Kadener, J. Fededa, M. Rosbash, and A. Kornblihtt, Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation, Proceedings of the National Academy of Sciences, vol.26, issue.24, pp.8185-8190, 2002.
DOI : 10.1093/nar/26.24.5568

K. Kadler, A. Hill, and E. Canty-laird, Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators, Current Opinion in Cell Biology, vol.20, issue.5, pp.495-501, 2008.
DOI : 10.1016/j.ceb.2008.06.008

R. Karni, E. De-stanchina, S. Lowe, R. Sinha, D. Mu et al., The gene encoding the splicing factor SF2/ASF is a proto-oncogene, Nature Structural & Molecular Biology, vol.66, issue.3, pp.185-193, 2007.
DOI : 10.1038/sj.onc.1202835

B. Kuo, T. Uporova, H. Liang, V. Bennett, R. Tuan et al., Alternative splicing during chondrogenesis: Modulation of fibronectin exon EIIIA splicing by SR proteins, Journal of Cellular Biochemistry, vol.270, issue.1, pp.45-55, 2002.
DOI : 10.1074/jbc.270.16.9486


Y. Abe, N. Bui-thanh, C. Ballantyne, and A. Burns, Extra domain A and type III connecting segment of fibronectin in assembly and cleavage, Biochemical and Biophysical Research Communications, vol.338, issue.3, pp.1640-1647, 2005.
DOI : 10.1016/j.bbrc.2005.10.134

A. Al-ayoubi, H. Zheng, Y. Liu, T. Bai, and S. Eblen, Mitogen-Activated Protein Kinase Phosphorylation of Splicing Factor 45 (SPF45) Regulates SPF45 Alternative Splicing Site Utilization, Proliferation, and Cell Adhesion, Molecular and Cellular Biology, vol.32, issue.14, pp.2880-2893, 2012.
DOI : 10.1128/MCB.06327-11

J. Aplin, T. Haigh, C. Jones, H. Church, and L. Vicovac, Development of Cytotrophoblast Columns from Explanted First-Trimester Human Placental Villi: Role of Fibronectin and Integrin ??5??11, Biology of Reproduction, vol.120, issue.4, pp.828-838, 1999.
DOI : 10.1126/science.277.5332.1669

S. Astrof, D. Crowley, and R. Hynes, Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin, Developmental Biology, vol.311, issue.1, pp.11-24, 2007.
DOI : 10.1016/j.ydbio.2007.07.005

Y. Barash, J. Calarco, W. Gao, Q. Pan, X. Wang et al., Deciphering the splicing code, Nature, vol.27, issue.7294, pp.53-59, 2010.
DOI : 10.1128/MCB.18.7.3900

D. Barkan, J. Green, and A. Chambers, Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth, European Journal of Cancer, vol.46, issue.7, pp.1181-1188, 2010.
DOI : 10.1016/j.ejca.2010.02.027

P. Bischof, L. Haenggeli, and A. Campana, Gelatinase and oncofetal fibronectin secretion is dependent on integrin expression on human cytotrophoblasts, Molecular Human Reproduction, vol.1, issue.1, pp.734-742, 1995.
DOI : 10.1093/molehr/1.1.36

, Molecular Biology of the Cell

R. Pankov and K. Yamada, Non-Radioactive Quantification of Fibronectin Matrix Assembly, Current Protocols in Cell Biology, vol.277, issue.1, 2004.
DOI : 10.1074/jbc.M200270200

D. Peters, L. Portz, J. Fullenwider, and D. Mosher, Co-assembly of plasma and cellular fibronectins into fibrils in human fibroblast cultures, The Journal of Cell Biology, vol.111, issue.1, pp.249-256, 1990.
DOI : 10.1083/jcb.111.1.249

J. Rinn, C. Bondre, H. Gladstone, P. Brown, and H. Chang, Anatomic Demarcation by Positional Variation in Fibroblast Gene Expression Programs, PLoS Genetics, vol.6, issue.7, p.119, 2006.
DOI : 10.1371/journal.pgen.0020119.st001

J. Rybak, C. Roesli, M. Kaspar, A. Villa, and D. Neri, The Extra-domain A of Fibronectin Is a Vascular Marker of Solid Tumors and Metastases, Cancer Research, vol.67, issue.22, pp.10948-10957, 2007.
DOI : 10.1158/0008-5472.CAN-07-1436

S. Sen, I. Talukdar, and N. Webster, SRp20 and CUG-BP1 Modulate Insulin Receptor Exon 11 Alternative Splicing, Molecular and Cellular Biology, vol.29, issue.3, pp.871-880, 2009.
DOI : 10.1128/MCB.01709-08

P. Singh, C. Carraher, and J. Schwarzbauer, Assembly of Fibronectin Extracellular Matrix, Annual Review of Cell and Developmental Biology, vol.26, issue.1, pp.397-419, 2010.
DOI : 10.1146/annurev-cellbio-100109-104020

R. Sinha, E. Allemand, Z. Zhang, R. Karni, M. Myers et al., Arginine Methylation Controls the Subcellular Localization and Functions of the Oncoprotein Splicing Factor SF2/ASF, Molecular and Cellular Biology, vol.30, issue.11, pp.2762-2774, 2010.
DOI : 10.1128/MCB.01270-09

J. Sottile, F. Shi, I. Rublyevska, H. Chiang, L. J. Chandler et al., Fibronectin-dependent collagen I deposition modulates the cell response to fibronectin, American Journal of Physiology-Cell Physiology, vol.293, issue.6, pp.1934-1946, 2007.
DOI : 10.1074/jbc.M312609200

R. Soundararajan and A. Rao, Trophoblast " pseudo-tumorigenesis " : significance and contributory factors, Reproductive Biology and Endocrinology, vol.2, issue.1, p.15, 2004.
DOI : 10.1186/1477-7827-2-15

S. Sun, Z. Zhang, R. Sinha, R. Karni, and A. Krainer, SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control, Nature Structural & Molecular Biology, vol.30, issue.3, pp.306-312, 2010.
DOI : 10.1128/MCB.16.1.146

C. Valacca, S. Bonomi, E. Buratti, S. Pedrotti, F. Baralle et al., Sam68 regulates EMT through alternative splicing???activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene, The Journal of Cell Biology, vol.164, issue.1, pp.87-99, 2010.
DOI : 10.1038/nature07509

J. Venables, RBFOX2 Is an Important Regulator of Mesenchymal Tissue-Specific Splicing in both Normal and Cancer Tissues, Molecular and Cellular Biology, vol.33, issue.2, pp.396-405, 2013.
DOI : 10.1128/MCB.01174-12

E. Wang, R. Sandberg, S. Luo, I. Khrebtukova, L. Zhang et al., Alternative isoform regulation in human tissue transcriptomes, Nature, vol.15, issue.7221, pp.470-476, 2008.
DOI : 10.1038/nature07509

E. White, F. Baralle, and A. Muro, New insights into form and function of fibronectin splice variants, The Journal of Pathology, vol.4, issue.1, pp.1-14, 2008.
DOI : 10.1161/01.ATV.18.9.1363

E. White, Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway, Experimental Cell Research, vol.316, issue.16, pp.2644-2653, 2010.
DOI : 10.1016/j.yexcr.2010.06.028

A. Zahler, K. Neugebauer, J. Stolk, and M. Roth, Human SR proteins and isolation of a cDNA encoding SRp75., Molecular and Cellular Biology, vol.13, issue.7, pp.4023-4028, 1993.
DOI : 10.1128/MCB.13.7.4023

N. Zoppi, M. Ritelli, and M. Colombi, Type III and V collagens modulate the expression and assembly of EDA+ fibronectin in the extracellular matrix of defective Ehlers???Danlos syndrome fibroblasts, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1820, issue.10, pp.1576-1587, 2012.
DOI : 10.1016/j.bbagen.2012.06.004

M. Leiss, K. Beckmann, A. Giros, M. Costell, and R. Fassler, The role of integrin binding sites in fibronectin matrix assembly in vivo, Current Opinion in Cell Biology, vol.20, issue.5, pp.502-507, 2008.
DOI : 10.1016/j.ceb.2008.06.001

R. Luco, M. Allo, I. Schor, A. Kornblihtt, and T. Misteli, Epigenetics in Alternative Pre-mRNA Splicing, Cell, vol.144, issue.1, pp.16-26, 2011.
DOI : 10.1016/j.cell.2010.11.056

R. Luco, Q. Pan, K. Tominaga, B. Blencowe, O. Pereira-smith et al., Regulation of Alternative Splicing by Histone Modifications, Science, vol.27, issue.7, pp.996-1000, 2010.
DOI : 10.1038/nbt.1550

P. Lu, V. Weaver, and Z. Werb, The extracellular matrix: A dynamic niche in cancer progression, The Journal of Cell Biology, vol.62, issue.4, pp.395-406, 2012.
DOI : 10.1002/1097-0142(19950215)75:4<1010::AID-CNCR2820750417>3.0.CO;2-O

R. Manabe, N. Ohe, T. Maeda, T. Fukuda, and K. Sekiguchi, Modulation of Cell-adhesive Activity of Fibronectin by the Alternatively Spliced EDA Segment, The Journal of Cell Biology, vol.6, issue.1, pp.295-307, 1997.
DOI : 10.1021/bi00644a025

Y. Mao and J. Schwarzbauer, Fibronectin fibrillogenesis, a cell-mediated matrix assembly process, Matrix Biology, vol.24, issue.6, pp.389-399, 2005.
DOI : 10.1016/j.matbio.2005.06.008

P. Mckeown-longo and C. Etzler, Induction of fibronectin matrix assembly in human fibrosarcoma cells by dexamethasone, The Journal of Cell Biology, vol.104, issue.3, pp.601-610, 1987.
DOI : 10.1083/jcb.104.3.601

J. Mermoud, P. Cohen, and A. Lamond, Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism, EMBO J, vol.13, pp.5679-5688, 1994.

T. Misteli, J. Caceres, J. Clement, A. Krainer, M. Wilkinson et al., Serine Phosphorylation of SR Proteins Is Required for Their Recruitment to Sites of Transcription In Vivo, The Journal of Cell Biology, vol.12, issue.2, pp.297-307, 1998.
DOI : 10.1038/372809a0

T. Misteli, J. Caceres, and D. Spector, The dynamics of a pre-mRNA splicing factor in living cells, Nature, vol.387, issue.6632, pp.523-527, 1997.
DOI : 10.1038/387523a0

F. Moretti, A. Chauhan, A. Iaconcig, F. Porro, F. Baralle et al., A Major Fraction of Fibronectin Present in the Extracellular Matrix of Tissues Is Plasma-derived, Journal of Biological Chemistry, vol.109, issue.38, pp.28057-28062, 2007.
DOI : 10.1074/jbc.M406283200

M. Munoz, M. De-la-mata, and A. Kornblihtt, The carboxy terminal domain of RNA polymerase II and alternative splicing, Trends in Biochemical Sciences, vol.35, issue.9, pp.497-504, 2010.
DOI : 10.1016/j.tibs.2010.03.010

A. Muro, A. Chauhan, S. Gajovic, A. Iaconcig, F. Porro et al., Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan, The Journal of Cell Biology, vol.6, issue.1, pp.149-160, 2003.
DOI : 10.1016/S0092-8674(02)00636-0

D. Nguyen, P. Bos, and J. Massague, Metastasis: from dissemination to organ-specific colonization, Nature Reviews Cancer, vol.100, issue.4, pp.274-284, 2009.
DOI : 10.1016/S0002-9440(10)65628-3

G. Nogues, S. Kadener, P. Cramer, D. Bentley, and A. Kornblihtt, Transcriptional Activators Differ in Their Abilities to Control Alternative Splicing, Journal of Biological Chemistry, vol.414, issue.45, pp.43110-43114, 2002.
DOI : 10.1093/nar/26.24.5568

G. Nogués, M. Muñoz, and A. Kornblihtt, Influence of Polymerase II Processivity on Alternative Splicing Depends on Splice Site Strength, Journal of Biological Chemistry, vol.19, issue.52, pp.52166-52171, 2003.
DOI : 10.1128/MCB.19.4.2657

E. Norwitz, D. Schust, and S. Fisher, Implantation and the Survival of Early Pregnancy, New England Journal of Medicine, vol.345, issue.19, pp.1400-1408, 2001.
DOI : 10.1056/NEJMra000763

S. Paget, THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST., The Lancet, vol.133, issue.3421, pp.571-573, 1889.
DOI : 10.1016/S0140-6736(00)49915-0