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Klüver & Bucy Syndrome: An investigation of social and affective cognition

Abstract : Klüver-Bucy syndrome (KBS) leads to important behavioural symptoms and social maladaptation. Rarely described in humans, no previous study has investigated the social and affective cognitive profile of KBS. Here, we report the case of ASP, a patient with history of herpetic encephalitis who developed a complete KBS at 9 years old that evolved into an incomplete KBS. Imaging examinations evidenced orbitofrontal and temporal damages. While a classic neuropsychological assessment showed a preserved global functioning, an extensive evaluation of her social and affective cognition (reversal-learning, decision-making, emotion recognition, theory of mind, creative-thinking) showed remarkable deficits. The relevancy of such findings for the characterization of cognitive damage in KBS and the field of neuropsychology are discussed.
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Maxime Bertoux, Elisa de Paula França Resende, Leonardo Cruz de Souza. Klüver & Bucy Syndrome: An investigation of social and affective cognition. Neurocase, Taylor & Francis (Routledge), In press, Epub ahead of print. ⟨inserm-01848640⟩



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