Biphasic Effect of Prostaglandin E2 on Osteoclast Formation in Spleen Cell Cultures: Role of the EP2 Receptor, Journal of Bone and Mineral Research, vol.18, issue.1, pp.23-29, 2005. ,
DOI : 10.4049/jimmunol.165.8.4254
PGE2 Signaling Through the EP4 Receptor on Fibroblasts Upregulates RANKL and Stimulates Osteolysis, Journal of Bone and Mineral Research, vol.24, issue.10, pp.1753-1762, 2009. ,
DOI : 10.1359/jbmr.090412
Fatty Acid Substrate Specificities of Human Prostaglandin-endoperoxide H Synthase-1 and ???2, Journal of Biological Chemistry, vol.265, issue.33, pp.19330-19336, 1995. ,
DOI : 10.1002/oms.1210010413
Effects of prostaglandin E3 and eicosapentaenoic acid on rat bone in organ culture, Prostaglandins, vol.37, issue.5, pp.615-625, 1989. ,
DOI : 10.1016/0090-6980(89)90076-2
Effects of dietary fats on bone health in advanced age, Prostaglandins, Leukotrienes and Essential Fatty Acids, vol.68, issue.6, pp.379-386, 2003. ,
DOI : 10.1016/S0952-3278(03)00062-0
n???3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases, The American Journal of Clinical Nutrition, vol.24, issue.6, pp.1505-1519, 2006. ,
DOI : 10.1016/j.it.2003.10.002
High Fatty Acid Content in Rabbit Serum Is Responsible for the Differentiation of Osteoblasts Into Adipocyte-like Cells, Journal of Bone and Mineral Research, vol.10, issue.1, pp.96-106, 1998. ,
DOI : 10.1074/jbc.270.5.2367
Expression of PPAR?? and ??/?? in Human Primary Osteoblastic Cells: Influence of Polyunsaturated Fatty Acids, Calcified Tissue International, vol.37, issue.suppl 1, pp.385-392, 2005. ,
DOI : 10.1038/sj.embor.7400254
Activation of Peroxisome Proliferator-activated Receptor-?? Inhibits the Runx2-mediated Transcription of Osteocalcin in Osteoblasts, Journal of Biological Chemistry, vol.113, issue.26, pp.23270-23277, 2003. ,
DOI : 10.1210/jc.86.2.828
Modulation of the expression of cyclooxygenase-2 by fatty acids mediated through Toll-like receptor 4-derived signaling pathways, The FASEB Journal, vol.15, issue.14, pp.2556-2564, 2001. ,
DOI : 10.1074/jbc.274.12.8328
TLR4 links innate immunity and fatty acid???induced insulin resistance, Journal of Clinical Investigation, vol.116, issue.11, pp.3015-3025, 2006. ,
DOI : 10.1172/JCI28898
Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice, Diabetologia, vol.27, issue.2, pp.318-328, 2009. ,
DOI : 10.4049/jimmunol.173.10.5901
is critical for diet-induced metabolic syndrome in a murine model, The FASEB Journal, vol.24, issue.3, pp.731-739, 2010. ,
DOI : 10.2337/diacare.27.6.1487
A genetic basis for the ???Adonis??? phenotype of low adiposity and strong bones, The FASEB Journal, vol.18, issue.11, pp.1282-1284, 2004. ,
DOI : 10.1096/fj.04-1572fje
The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids, Journal of Biological Chemistry, vol.9, issue.13, pp.11303-11311, 2003. ,
DOI : 10.1007/978-1-4615-4861-4_7
Free fatty acids regulate insulin secretion from pancreatic ?? cells through GPR40, Nature, vol.16, issue.6928, pp.173-176, 2003. ,
DOI : 10.2337/diab.16.1.35
Progress in Methodology Improved Reporter Gene Assays Used to Identify Ligands Acting on Orphan Seven-Transmembrane Receptors, Pharmacology and Toxicology, vol.59, issue.6, pp.249-258, 2003. ,
DOI : 10.1126/science.279.5347.84
The G-protein-coupled receptor 40 family (GPR40???GPR43) and its role in nutrient sensing, Biochemical Society Transactions, vol.34, issue.5, pp.770-773, 2006. ,
DOI : 10.1042/BST0340770
GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo, Diabetes, vol.56, issue.4, pp.1087-1094, 2007. ,
DOI : 10.2337/db06-1532
GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes, Diabetes, Obesity and Metabolism, vol.1, issue.Suppl 2, pp.271-278, 2012. ,
DOI : 10.1007/s13340-010-0006-7
TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial, The Lancet, vol.379, issue.9824, pp.1403-1411, 2012. ,
DOI : 10.1016/S0140-6736(11)61879-5
Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids, Biochemical and Biophysical Research Communications, vol.303, issue.4, pp.1047-1052, 2003. ,
DOI : 10.1016/S0006-291X(03)00488-1
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects, Cell, vol.142, issue.5, pp.687-698, 2010. ,
DOI : 10.1016/j.cell.2010.07.041
Modulation of Osteoclastogenesis by Fatty Acids, Endocrinology, vol.149, issue.11, pp.5688-5695, 2008. ,
DOI : 10.1210/en.2008-0111
URL : https://academic.oup.com/endo/article-pdf/149/11/5688/8998212/endo5688.pdf
Thiazolidinediones Induce Osteocyte Apoptosis by a G Protein-coupled Receptor 40-dependent Mechanism, Journal of Biological Chemistry, vol.2, issue.28, pp.23517-23526, 2012. ,
DOI : 10.1210/en.140.11.5060
URL : http://www.jbc.org/content/287/28/23517.full.pdf
High d(+)glucose concentration inhibits RANKL-induced osteoclastogenesis, Bone, vol.42, issue.6, pp.1122-1130, 2008. ,
DOI : 10.1016/j.bone.2008.02.006
URL : http://europepmc.org/articles/pmc2696157?pdf=render
, GPR40 Activation Protects from Bone Loss
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules, British Journal of Pharmacology, vol.43, issue.Suppl 2, pp.619-628, 2006. ,
DOI : 10.1016/S1388-1981(02)00342-6
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis, The Journal of Experimental Medicine, vol.96, issue.9, pp.1261-1269, 2005. ,
DOI : 10.1007/s00109-004-0612-6
Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets, Diabetes, vol.58, issue.11, pp.2607-2615, 2009. ,
DOI : 10.2337/db09-0362
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice., Endocrinology, vol.137, issue.10, pp.4189-4195, 1996. ,
DOI : 10.1210/endo.137.10.8828476
The Peroxisome Proliferator Activator Receptor Alpha/Delta Agonists Linoleic Acid and Bezafibrate Upregulate Osteoblast Differentiation and Induce Periosteal Bone Formation In Vivo, Calcified Tissue International, vol.302, issue.4, pp.285-292, 2008. ,
DOI : 10.1007/s00223-008-9175-9
PPAR agonists modulate human osteoclast formation and activity in vitro, Bone, vol.40, issue.1, pp.149-159, 2007. ,
DOI : 10.1016/j.bone.2006.07.029
Activation of peroxisome proliferator-activated receptor ?? inhibits TNF-??-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression, Bone, vol.42, issue.4, pp.765-774, 2008. ,
DOI : 10.1016/j.bone.2007.11.016
PPAR-?? regulates osteoclastogenesis in mice, Nature Medicine, vol.13, issue.12, pp.1496-1503, 2007. ,
DOI : 10.1172/JCI24130
Cloning and Function of Rabbit Peroxisome Proliferator-activated Receptor ??/?? in Mature Osteoclasts, Journal of Biological Chemistry, vol.17, issue.11, pp.8126-8132, 2000. ,
DOI : 10.1038/386081a0
The Action and Mode of Binding of Thiazolidinedione Ligands at Free Fatty Acid Receptor 1, Journal of Biological Chemistry, vol.250, issue.26, pp.17527-17539, 2009. ,
DOI : 10.1007/978-1-59745-205-2_8
Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor, American Journal of Physiology-Lung Cellular and Molecular Physiology, vol.296, issue.6, pp.970-978, 2009. ,
DOI : 10.1056/NEJMra041001
Saturated fatty acids enhance osteoclast survival, Journal of Lipid Research, vol.96, issue.5, pp.892-899, 2010. ,
DOI : 10.1016/S0303-7207(01)00394-X