5UNH - Unité de Nutrition Humaine (Site INRAE Theix : 63122 Saint-Gènes-Champanelle // Site Clermont : UFR de Médecine et de Pharmacie, TSA 50400, 28 Place Henri Dunant, 63001 Clermont-Ferrand - France)
6UNH - Unité de Nutrition Humaine (Site INRAE Theix : 63122 Saint-Gènes-Champanelle // Site Clermont : UFR de Médecine et de Pharmacie, TSA 50400, 28 Place Henri Dunant, 63001 Clermont-Ferrand - France)
Abstract : Osteoarthritis (OA) is a degenerative joint disease with no curative treatments. Many studies have begun to demonstrate the efficacy of nutraceuticals for slowing down OA. Animal models are utilized as a compulsory step in demonstrating the protective potential of these compounds on joint health. Nevertheless, there exist a wide variety of available OA models and selecting a suitable system for evaluating the effects of a specific compound remains difficult. Here, we discuss animal studies that have
investigated nutraceutical effects on OA. In particular, we highlight the large spectrum of animal models that are currently accepted for examining the OA-related effects of nutraceuticals, giving recommendations for their use.
https://www.hal.inserm.fr/inserm-01847472
Contributor : Valérie Pecqueret <>
Submitted on : Monday, July 23, 2018 - 3:49:38 PM Last modification on : Thursday, March 4, 2021 - 10:52:04 AM Long-term archiving on: : Wednesday, October 24, 2018 - 3:53:40 PM
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