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Journal Articles Acta Orthopaedica Year : 2016

Ageing in the musculoskeletal system

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Abstract

The extent of ageing in the musculoskeletal system during the life course affects the quality and length of life. Loss of bone, degraded articular cartilage, and degenerate, narrowed intervertebral discs are primary features of an ageing skeleton, and together they contribute to pain and loss of mobility. This review covers the cellular constituents that make up some key components of the musculoskeletal system and summarizes discussion from the 2015 Aarhus Regenerative Orthopaedic Symposium (AROS) (Regeneration in the Ageing Population) about how each particular cell type alters within the ageing skeletal microenvironment.
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Dates and versions

inserm-01845546 , version 1 (20-07-2018)

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Sally Roberts, Pauline Colombier, Aneka Sowman, Claire Mennan, Jan H D Rölfing, et al.. Ageing in the musculoskeletal system. Acta Orthopaedica, 2016, 87 (sup363), pp.15 - 25. ⟨10.1080/17453674.2016.1244750⟩. ⟨inserm-01845546⟩
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