C. ). Berger-saint-etienne and C. Bergeron,

P. Bordigoni, N. ). , P. Boutard-caen-), and P. Chastagner, Geneviève Margueritte (H^ opital Arnaud de Villeneuve Yves Perel (H^ opital Pellegrin Tripode The authors thank all families for their generous participation, Virginie Gandemer (Centre Hospitalier Universitaire ? H^ opital Sud, Rennes), St ephanie Haouy (H^ opital Arnaud de Villeneuve, Montpellier), Jean-Pierre Lamagnere (Centre Gatien de Clocheville Françoise Mechinaud Martine M? unzer (American Memorial Hospital Marilyne Poiree (Fondation Lenval Nicolas Sirvent (H^ opital Arnaud de Villeneuve) and Jean-Pierre Vannier

, References

B. Lacour, A. Guyot-goubin, and S. Guissou, Incidence of childhood cancer in France: National Children Cancer Registries, 2000???2004, European Journal of Cancer Prevention, vol.19, issue.3, pp.173-81, 2000.
DOI : 10.1097/CEJ.0b013e32833876c0

K. Johnson, J. Cullen, and J. Barnholtz-sloan, Childhood Brain Tumor Epidemiology: A Brain Tumor Epidemiology Consortium Review, Cancer Epidemiology Biomarkers & Prevention, vol.23, issue.12, pp.2716-2752, 2014.
DOI : 10.1158/1055-9965.EPI-14-0207

D. Vienneau, D. Infanger, and M. Feychting, A multinational case-control study on childhood brain tumours, anthropogenic factors, birth characteristics and prenatal exposures: A validation of interview data, Cancer Epidemiology, vol.40, pp.52-61, 2016.
DOI : 10.1016/j.canep.2015.11.006

S. Oksuzyan, C. Crespi, and M. Cockburn, Birth weight and other perinatal factors and childhood CNS tumors: A case???control study in California, Cancer Epidemiology, vol.37, issue.4, pp.402-411, 2013.
DOI : 10.1016/j.canep.2013.03.007

O. Neill, K. Murphy, M. Bunch, and K. , I n f a n t birthweight and risk of childhood cancer: international population-based case control studies of 40 000 cases, Int J Epidemiol, vol.44, pp.153-68, 2015.

M. Sprehe, N. Barahmani, and Y. Cao, Comparison of birth weight corrected for gestational age and birth weight alone in prediction of development of childhood leukemia and central nervous system tumors, Pediatric Blood & Cancer, vol.6, pp.242-251, 2010.
DOI : 10.1515/JPEM.2000.13.3.289

J. Maclean, S. Partap, and P. Reynolds, B i r t hw e i g h t and order as risk factors for childhood central nervous system tumors. JP e d i a t r2010, pp.450-455

L. Schmidt, J. Schuz, and P. Lahteenmaki, Fetal Growth, Preterm Birth, Neonatal Stress and Risk for CNS Tumors in Children: A Nordic Population- and Register-Based Case-Control Study, Cancer Epidemiology Biomarkers & Prevention, vol.19, issue.4, pp.1042-52, 2010.
DOI : 10.1158/1055-9965.EPI-09-1273

T. Bjorge, H. Sorensen, and T. Grotmol, Fetal Growth and Childhood Cancer: A Population-Based Study, PEDIATRICS, vol.132, issue.5, pp.1265-75, 2013.
DOI : 10.1542/peds.2013-1317

C. Crump, J. Sundquist, and W. Sieh, Perinatal and Familial Risk Factors for Brain Tumors in Childhood through Young Adulthood, Cancer Research, vol.75, issue.3, pp.576-83, 2015.
DOI : 10.1158/0008-5472.CAN-14-2285

K. Greenop, E. Blair, and C. Bower, Factors relating to pregnancy and birth and the risk of childhood brain tumors: Results from an Australian case-control study, Pediatric Blood & Cancer, vol.145, issue.3, pp.493-501, 2014.
DOI : 10.1093/oxfordjournals.aje.a009032

E. Milne, K. Greenop, and C. Bower, Maternal Use of Folic Acid and Other Supplements and Risk of Childhood Brain Tumors, Cancer Epidemiology Biomarkers & Prevention, vol.21, issue.11, pp.1933-1974, 2012.
DOI : 10.1158/1055-9965.EPI-12-0803

J. Ortega-garcia, J. Ferris-tortajada, and L. Claudio, Case control study of periconceptional folic acid intake and nervous system tumors in children, Child's Nervous System, vol.44, issue.No. RR-14, pp.1727-1760, 2010.
DOI : 10.7326/0003-4819-129-7-199810010-00002

G. Bunin, P. Gallagher, and L. Rorke-adams, Maternal Supplement, Micronutrient, and Cured Meat Intake during Pregnancy and Risk of Medulloblastoma during Childhood: A Children's Oncology Group Study, Cancer Epidemiology Biomarkers & Prevention, vol.15, issue.9, pp.1660-1667, 2006.
DOI : 10.1158/1055-9965.EPI-06-0254

G. Bunin, R. Kuijten, and J. Buckley, Relation between Maternal Diet and Subsequent Primitive Neuroectodermal Brain Tumors in Young Children, New England Journal of Medicine, vol.329, issue.8, pp.536-577, 1993.
DOI : 10.1056/NEJM199308193290804

J. Mortensen, N. Oyen, and T. Fomina, Supplemental folic acid in pregnancy and childhood cancer risk, British Journal of Cancer, vol.87, issue.1, pp.71-76, 2016.
DOI : 10.1136/bmj.39079.618287.0B

S. Gonseth, R. Roy, and E. Houseman, Periconceptional folate consumption is associated with neonatal DNA methylation modifications in neural crest regulatory and cancer development genes, Epigenetics, vol.65, issue.12, pp.1166-76, 2015.
DOI : 10.1038/ng1180

R. Martin, D. Gunnell, C. Owen, and G. Smith, Breast-feeding and childhood cancer: A systematic review with metaanalysis, International Journal of Cancer, vol.9, issue.6, pp.1020-1051, 2005.
DOI : 10.1016/S0140-6736(00)82011-5

K. Greenop, H. Bailey, and M. Miller, Breastfeeding and Nutrition to 2 Years of Age and Risk of Childhood Acute Lymphoblastic Leukemia and Brain Tumors, Nutrition and Cancer, vol.3, issue.3, pp.431-441, 2015.
DOI : 10.1186/1471-2288-12-179

P. Rios, H. Bailey, and L. Orsi, Risk of neuroblastoma, birth-related characteristics, congenital malformations and perinatal exposures: A pooled analysis of the ESCALE and ESTELLE French studies (SFCE), International Journal of Cancer, vol.23, issue.9, pp.1936-1984, 2016.
DOI : 10.1200/JCO.2005.05.571

URL : https://hal.archives-ouvertes.fr/hal-01482620

P. Mckinney, E. Juszczak, and E. Findlay, Pre- and perinatal risk factors for childhood leukaemia and other malignancies: a Scottish case control study, British Journal of Cancer, vol.80, issue.11, pp.1844-51, 1999.
DOI : 10.1038/sj.bjc.6690609

J. Schuz, U. Kaletsch, and P. Kaatsch, Risk factors for pediatric tumors of the central nervous system: Results from a German population-based case-control study, Medical and Pediatric Oncology, vol.34, issue.2, pp.274-82, 2001.
DOI : 10.1038/bjc.1997.22

N. Harding, J. Birch, S. Hepworth, and P. Mckinney, Breastfeeding and risk of childhood CNS tumours, British Journal of Cancer, vol.9, issue.5, pp.815-822, 2007.
DOI : 10.1016/S0140-6736(00)82011-5

L. Hardell and A. Dreifaldt, Breast-feeding duration and the risk of malignant diseases in childhood in Sweden, European Journal of Clinical Nutrition, vol.55, issue.3, pp.179-85, 2001.
DOI : 10.1038/sj.ejcn.1601142

C. Chen, T. Xu, and J. Chen, Allergy and risk of glioma: a meta-analysis, European Journal of Neurology, vol.6, issue.3, pp.387-95, 2011.
DOI : 10.1038/74710

N. Harding, J. Birch, S. Hepworth, and P. Mckinney, Atopic dysfunction and risk of central nervous system tumours in children, European Journal of Cancer, vol.44, issue.1, pp.92-101, 2008.
DOI : 10.1016/j.ejca.2007.10.007

F. Roncarolo and C. Infante-rivard, Asthma and risk of brain cancer in children, Cancer Causes & Control, vol.10, issue.3, pp.617-640, 2012.
DOI : 10.1016/S0140-6736(06)69283-0

S. Carozza, P. Langlois, E. Miller, and M. Canfield, Are Children With Birth Defects at Higher Risk of Childhood Cancers?, American Journal of Epidemiology, vol.1, issue.2, pp.1217-1241, 2012.
DOI : 10.1038/35101031

T. Bjorge, S. Cnattingius, and R. Lie, Cancer Risk in Children with Birth Defects and in Their Families: A Population Based Cohort Study of 5.2 Million Children from Norway and Sweden, Cancer Epidemiology Biomarkers & Prevention, vol.17, issue.3, pp.500-506, 2008.
DOI : 10.1158/1055-9965.EPI-07-2630

K. Sundh, A. Henningsen, and K. Kallen, Cancer in children and young adults born after assisted reproductive technology: a Nordic cohort study from the Committee of Nordic ART and Safety (CoNARTaS), Human Reproduction, vol.369, issue.8730, pp.2050-2057, 2014.
DOI : 10.1056/NEJMoa1301675

M. Hargreave, A. Jensen, and I. Deltour, Increased risk for cancer among offspring of women with fertility problems, International Journal of Cancer, vol.132, issue.5, pp.1180-1186, 2013.
DOI : 10.1093/rpd/ncn261

M. Hargreave, A. Jensen, and A. Toender, Fertility treatment and childhood cancer risk: a systematic meta-analysis, Fertility and Sterility, vol.100, issue.1, pp.150-61, 2013.
DOI : 10.1016/j.fertnstert.2013.03.017

N. Mallol-mesnard, F. Menegaux, and B. Lacour, Birth characteristics and childhood malignant central nervous sytem tumors: The ESCALE study (French Society for Childhood Cancer), Cancer Detection and Prevention, vol.32, issue.1, pp.79-86, 2008.
DOI : 10.1016/j.cdp.2008.02.003

URL : https://hal.archives-ouvertes.fr/inserm-00273538

R. Ajrouche, J. Rudant, and L. Orsi, Maternal reproductive history, fertility treatments and folic acid supplementation in the risk of childhood acute leukemia: the ESTELLE Study, Cancer Causes & Control, vol.86, issue.10, pp.1283-93, 2014.
DOI : 10.1038/sj.bjc.6600091

URL : https://hal.archives-ouvertes.fr/hal-01064579

E. Steliarova-foucher, C. Stiller, B. Lacour, and P. Kaatsch, International Classification of Childhood Cancer, third edition, Cancer, vol.82, issue.7, pp.1457-67, 2005.
DOI : 10.1016/S1043-0679(99)70069-9

, AUDiPOG) Morphom etrie n eonatale. Poids, taille et p erimètre cr^ anien al a naissance: Calcul des Z scores et des centiles en fonction de l';^ age gestationnel et du sexeed, 2008.

, Weight gain during pregnancy; Reexamining the guidelines Available at: https, 2009.

C. Bower, R. E. Quick, and J. , Western Australian Regiser of Developmental anomalies 1980- 2013. Subiaco: Government of Western Australia Department of Health, 2015.

J. Tort, N. Lelong, and C. Prunet, Maternal and health care determinants of preconceptional use of folic acid supplementation in France: results from the 2010 National Perinatal Survey, BJOG: An International Journal of Obstetrics & Gynaecology, vol.65, issue.54, pp.1661-1668, 2013.
DOI : 10.1301/nr.2007.nov.504-511

B. Blondel, N. Lelong, M. Kermarrec, and F. Goffinet, Trends in perinatal health in France from 1995 to 2010. Results from the French National Perinatal Surveys, Journal de Gyn??cologie Obst??trique et Biologie de la Reproduction, vol.41, issue.4, pp.1-15, 2012.
DOI : 10.1016/j.jgyn.2012.04.014

URL : https://hal.archives-ouvertes.fr/inserm-00857949

T. Harder, A. Plagemann, and A. Harder, Birth Weight and Subsequent Risk of Childhood Primary Brain Tumors: A Meta-Analysis, American Journal of Epidemiology, vol.17, issue.3, pp.366-73, 2008.
DOI : 10.1046/j.1365-3016.2003.00496.x

URL : https://academic.oup.com/aje/article-pdf/168/4/366/17337726/kwn144.pdf

K. Stalberg, B. Haglund, B. Stromberg, and H. Kieler, Prenatal exposure to medicines and the risk of childhood brain tumor, Cancer Epidemiology, vol.34, issue.4, p.400, 2010.
DOI : 10.1016/j.canep.2010.04.018

S. Preston-martin, J. Pogoda, and B. Mueller, Prenatal vitamin supplementation and risk of childhood brain tumors, International Journal of Cancer, vol.5, issue.S11, pp.17-22, 1998.
DOI : 10.1002/(SICI)1097-0215(1998)78:11+<17::AID-IJC6>3.0.CO;2-Q

C. Bower, M. Miller, J. Payne, and P. Serna, Promotion of folate for the prevention of neural tube defects: who benefits?, Paediatric and Perinatal Epidemiology, vol.38, issue.6, pp.435-479, 2005.
DOI : 10.1111/j.1365-3016.2004.00567.x

B. Blondel and M. Kermarrec, Enqu^ ete Nationale P erinatale 2010: Les naisssances en 2010 et leur evolution depuis Paris: Inserm Available from: http://social-sante. gouv, 2003.

G. Bunin, J. Buckley, and C. Boesel, Risk factors for astrocytic glioma and primitive neuroectodermal tumor of the brain in young children: a report from the Children's Cancer Group, Cancer Epidemiol Biomarkers Prev, vol.3, pp.197-204, 1994.

S. Dawson, A. Charles, and C. Bower, Risk of cancer among children with birth defects: A novel approach, Birth Defects Research Part A: Clinical and Molecular Teratology, vol.121, issue.4, pp.284-91, 2015.
DOI : 10.1002/cncr.20910

M. Mccredie, J. Little, and S. Cotton, SEARCH international case-control study of childhood brain tumours: role of index pregnancy and birth, and mother's reproductive history, Paediatric and Perinatal Epidemiology, vol.91, issue.3, pp.325-366, 1999.
DOI : 10.1093/oxfordjournals.aje.a121158

T. Heiden, H. Bailey, B. Armstrong, and E. Milne, Participation in paediatric cancer studies: timing and approach to recruitment, BMC Research Notes, vol.6, issue.1, p.191, 2013.
DOI : 10.1016/S0895-4356(98)00088-2

URL : https://bmcresnotes.biomedcentral.com/track/pdf/10.1186/1756-0500-6-191?site=bmcresnotes.biomedcentral.com