C. Pui, M. Relling, and J. Downing, Acute Lymphoblastic Leukemia, New England Journal of Medicine, vol.350, issue.15, pp.1535-1548, 2004.
DOI : 10.1056/NEJMra023001

M. Ciofani and J. Zuniga-pflucker, Notch promotes survival of pre???T cells at the ??-selection checkpoint by regulating cellular metabolism, Nature Immunology, vol.126, issue.9, pp.881-888, 2005.
DOI : 10.1042/bj1260525

V. Povoa, PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events, Blood, vol.124, pp.567-578, 2014.

M. Remke, S. Pfister, C. Kox, G. Toedt, N. Becker et al., High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-?? and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response, Blood, vol.114, issue.5, pp.1053-1062, 2009.
DOI : 10.1182/blood-2008-10-186536

M. Tesio, A. Trinquand, E. Macintyre, and V. Asnafi, Oncogenic PTEN functions and models in T-cell malignancies, Oncogene, vol.510, issue.30, pp.3887-3896, 2015.
DOI : 10.1101/gad.313104

V. Asnafi, A. Buzyn, L. Noir, S. Baleydier, F. Simon et al., NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study, Blood, vol.113, issue.17, pp.3918-3924, 2009.
DOI : 10.1182/blood-2008-10-184069

J. Bergeron, E. Clappier, I. Radford, A. Buzyn, C. Millien et al., Prognostic and oncogenic relevance of TLX1/HOX11 expression level in T-ALLs, Blood, vol.110, issue.7, pp.2324-2330, 2007.
DOI : 10.1182/blood-2007-04-079988

H. Li and R. Durbin, Fast and accurate long-read alignment with Burrows???Wheeler transform, Bioinformatics, vol.7, issue.5, pp.589-595, 2010.
DOI : 10.1089/10665270050081478

A. Mckenna, M. Hanna, E. Banks, A. Sivachenko, K. Cibulskis et al., The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data, Genome Research, vol.20, issue.9, pp.1297-1303, 2010.
DOI : 10.1101/gr.107524.110

H. Li, B. Handsaker, A. Wysoker, T. Fennell, J. Ruan et al., The Sequence Alignment/Map format and SAMtools, Bioinformatics, vol.9, issue.11, pp.2078-2079, 2009.
DOI : 10.1146/annurev.genom.9.081307.164359

I. Martincorena and P. Campbell, Somatic mutation in cancer and normal cells, Science, vol.502, issue.7155, pp.1483-1489, 2015.
DOI : 10.1038/nature12634

A. , W. L. Bonora, M. Salmena, L. Song, M. Hobbs et al., Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function, Cell, vol.157, pp.595-610, 2014.

V. Gianfelici, S. Chiaretti, S. Demeyer, D. Giacomo, F. Messina et al., RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications, Haematologica, vol.101, issue.8, pp.941-950, 2016.
DOI : 10.3324/haematol.2015.139410

URL : http://www.haematologica.org/content/haematol/101/8/941.full.pdf

, Supplementary Information accompanies this paper on the Leukemia website