, oncotarget USA), and Cal51 from DSMZ

E. The, MCF-10A cell line was a generous gift of, Dr Kevin Struhl (Harvard Medical School

, The ER-Src MCF-10A cells contain an integrated fusion of the v-Src oncoprotein and the ligandbinding domain of estrogen receptor and are induced to rapidly transform when grown with 1 ?M as previously described [13]. YM155, Necrostatin-1 and BAY11-7085 were purchased from Selleck Chemicals (Houston, USA) and the pan-caspase inhibitor Q-VD-OPh from R&DSystems Chloroquine, 3-Methyl-Adenin (3-MA), Bafilomycin A1 were purchased from Sigma-Aldrich (Saint- Quentin Yvelines, France) AS602868 was a generous gift of Merck-Serono International SA [14]. Antibodies against Survivin was purchased from R&DSystems, All cell lines were cultured following supplier's recommendations antibodies against LC3 antibodies against HSP90, p53 and cleaved (i.e. activated) caspase3 from Becton Dickinson antibody against BAX from Dako), and antibody against p62 from Santa Cruz, pp.15-53


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