L. M. Vrooman, L-Asparaginase Each Improve Outcome of Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia: Results From a Randomized Study???Dana-Farber Cancer Institute ALL Consortium Protocol 00-01, Journal of Clinical Oncology, vol.31, issue.9, pp.1202-1210, 2013.
DOI : 10.1200/JCO.2012.43.2070
URL : http://europepmc.org/articles/pmc3595424?pdf=render

B. Asselin and C. Rizzari, Asparaginase pharmacokinetics and implications of therapeutic drug monitoring, Leukemia & Lymphoma, vol.122, issue.1, pp.2273-2280, 2015.
DOI : 10.1182/blood-2014-02-553040
URL : http://europepmc.org/articles/pmc4732456?pdf=render

M. Jarrar, Asparagine depletion after pegylatedE. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: A Children's Oncology Group study (CCG-1941), Pediatric Blood & Cancer, vol.17, issue.2, pp.141-146, 2006.
DOI : 10.1093/oxfordjournals.annonc.a010722

M. Wetzler, Effective asparagine depletion with pegylated asparaginase results in improved outcomes in adult acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 9511, Blood, vol.109, issue.10, pp.4164-4167, 2007.
DOI : 10.1182/blood-2006-09-045351
URL : http://www.bloodjournal.org/content/bloodjournal/109/10/4164.full.pdf

E. H. Panosyan, Asparaginase Antibody and Asparaginase Activity in Children With Higher-Risk Acute Lymphoblastic Leukemia, Journal of Pediatric Hematology/Oncology, vol.26, issue.4, pp.217-226, 2004.
DOI : 10.1097/00043426-200404000-00002

F. Huguet, The upper age limit for a pediatric-like treatment in adult patients with acute lymphoblastic leukemia: report of the Graall-2005 study, Blood

S. Lepretre, Pediatric-Like Acute Lymphoblastic Leukemia Therapy in Adults With Lymphoblastic Lymphoma: The GRAALL-LYSA LL03 Study, Journal of Clinical Oncology, vol.34, issue.6, pp.572-580, 2016.
DOI : 10.1200/JCO.2015.61.5385
URL : https://hal.archives-ouvertes.fr/inserm-01411210

N. Dhédin, Role of allogeneic stem cell transplantation in adult patients with Ph-negative acute lymphoblastic leukemia, Blood, vol.125, issue.16, pp.2486-2496, 2015.
DOI : 10.1182/blood-2014-09-599894

S. Maury, Rituximab in B-Lineage Adult Acute Lymphoblastic Leukemia, New England Journal of Medicine, vol.375, issue.11, pp.1044-1053, 2016.
DOI : 10.1056/NEJMoa1605085

F. Méchinaud and N. H. Corradini, Asparaginase use: benefits and limits, Corresp. Oncohématol, vol.1, pp.39-45, 2006.

I. M. Van-der-sluis, Consensus expert recommendations for identification and management of asparaginase hypersensitivity and silent inactivation, Haematologica, vol.101, issue.3, pp.279-285, 2016.
DOI : 10.3324/haematol.2015.137380