Production and quality control of monoclonal antibodies and related substances, 2009. ,
Similar biological medicinal products [Internet], 2014. ,
Recombinant therapeutic monoclonal antibodies: mechanisms of action in relation to structural and functional duality, Crit Rev Oncol Hematol, vol.64, pp.226-259, 2007. ,
Rituximab-dependent cytotoxicity by natural killer cells: influence of FCGR3A polymorphism on the concentration-effect relationship, Cancer Res, vol.64, pp.4664-4673, 2004. ,
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor Fcgamma RIIIa gene, Blood, vol.99, issue.3, pp.754-762, 2002. ,
DOI : 10.1182/blood.V99.3.754
URL : http://www.bloodjournal.org/content/bloodjournal/99/3/754.full.pdf
???Positive Metastatic Breast Cancer, Journal of Clinical Oncology, vol.26, issue.11, pp.1789-96, 2008. ,
DOI : 10.1200/JCO.2007.14.8957
FCGR2A and FCGR3A Polymorphisms Associated With Clinical Outcome of Epidermal Growth Factor Receptor???Expressing Metastatic Colorectal Cancer Patients Treated With Single-Agent Cetuximab, Journal of Clinical Oncology, vol.25, issue.24, pp.3712-3720, 2007. ,
DOI : 10.1200/JCO.2006.08.8021
Superior In vivo Efficacy of Afucosylated Trastuzumab in the Treatment of HER2-Amplified Breast Cancer, Cancer Research, vol.70, issue.11, pp.4481-4490, 2010. ,
DOI : 10.1158/0008-5472.CAN-09-3704
Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity, Blood, vol.115, issue.22, pp.4393-402, 2009. ,
DOI : 10.1182/blood-2009-06-225979
GADOLIN: Primary results from a phase III study of obinutuzumab plus bendamustine compared with bendamustine alone in patients with rituximab-refractory indolent non-Hodgkin lymphoma., Journal of Clinical Oncology, vol.33, issue.18_suppl, p.8502, 2015. ,
DOI : 10.1200/jco.2015.33.18_suppl.lba8502
Obinutuzumab (GA101) in relapsed/refractory chronic lymphocytic leukemia: final data from the phase 1/2 GAUGUIN study, Blood, vol.124, issue.14, pp.2196-202, 2014. ,
DOI : 10.1182/blood-2014-07-586610
URL : https://hal.archives-ouvertes.fr/hal-01147035
Antibodies to watch in 2014, mAbs, vol.6, issue.1, pp.5-14, 2014. ,
DOI : 10.4161/mabs.2.1.10677
URL : http://www.tandfonline.com/doi/pdf/10.4161/mabs.27333?needAccess=true
Quantitative titration, kinetic behaviour, and inhibition of cytotoxic mouse isoantisera, Immunology, vol.9, pp.287-3005838200, 1965. ,
Quantitative assay of the lytic action of immune lymphoid cells of 51Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs, Immunology, vol.14, pp.181-964966657, 1968. ,
CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity, Journal of Immunological Methods, vol.172, issue.2, pp.227-390022, 1994. ,
DOI : 10.1016/0022-1759(94)90110-4
Determination of cytotoxic T lymphocyte activity by time-resolved fluorometry using europiumlabelled concanavalin A-stimulated cells as targets, J Immunol Methods, vol.11488, pp.191-50022, 1988. ,
DOI : 10.1016/0022-1759(88)90173-1
A Novel Method for Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry, PLOS ONE, vol.3, issue.16, 2015. ,
DOI : 10.1371/journal.pone.0141074.s002
URL : https://doi.org/10.1371/journal.pone.0141074
A novel non-radioactive cellular cytotoxicity test based on the differential assessment of living and killed target and effector cells, Journal of Immunological Methods, vol.180, issue.1, pp.1-137897241, 1995. ,
DOI : 10.1016/0022-1759(94)00293-6
Antibody-dependent cell-mediated cytotoxicity: a flow cytometry-based assay using fluorophores, Journal of Immunological Methods, vol.258, issue.1-2, pp.183-91, 2001. ,
DOI : 10.1016/S0022-1759(01)00474-4
A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis, Journal of Immunological Methods, vol.249, issue.1-2, pp.99-110, 2001. ,
DOI : 10.1016/S0022-1759(00)00329-X
An enzyme-release assay for natural cytotoxicity, Journal of Immunological Methods, vol.64, issue.3, pp.313-200022, 1983. ,
DOI : 10.1016/0022-1759(83)90438-6
A very sensitive coupled luminescent assay for cytotoxicity and complement-mediated lysis, Journal of Immunological Methods, vol.207, issue.1, pp.43-51, 1997. ,
DOI : 10.1016/S0022-1759(97)00098-7
Measurement of cytotoxicity by ATP-based luminescence assay in primary cell cultures and cell lines, Toxicology in Vitro, vol.11, issue.5, pp.553-559, 1997. ,
DOI : 10.1016/S0887-2333(97)00060-X
An impedance-based cytotoxicity assay for real-time and label-free assessment of T-cell-mediated killing of adherent cells, Journal of Immunological Methods, vol.405, pp.192-200, 2014. ,
DOI : 10.1016/j.jim.2014.01.012
gd T cell-mediated antibody-dependent cellular cytotoxicity with CD19 antibodies assessed by an impedance-based label-free real-time cytotoxicity assay, Front Immunol, vol.5, p.618, 2014. ,
DOI : 10.3389/fimmu.2014.00618
URL : http://journal.frontiersin.org/article/10.3389/fimmu.2014.00618/pdf
Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay, mAbs, vol.148, issue.3, pp.310-318, 2012. ,
DOI : 10.1038/nbt1026
URL : http://www.tandfonline.com/doi/pdf/10.4161/mabs.19873?needAccess=true
T Cells, The Journal of Experimental Medicine, vol.170, issue.7, pp.925-961, 2004. ,
DOI : 10.4049/jimmunol.170.2.805
Chronic lymphocytic leukaemia cells are efficiently killed by an anti-CD20 monoclonal antibody selected for improved engagement of Fc??RIIIA/CD16, British Journal of Haematology, vol.177, issue.6, pp.635-678, 2008. ,
DOI : 10.1200/JCO.2003.05.013
Combined Fc-protein- and Fc-glyco-engineering of scFv-Fc fusion proteins synergistically enhances CD16a binding but does not further enhance NK-cell mediated ADCC, Journal of Immunological Methods, vol.373, issue.1-2, pp.67-78, 2011. ,
DOI : 10.1016/j.jim.2011.08.003
Mechanisms of escape from Trastuzumab-mediated ADCC in esophageal squamous cell carcinoma: relation to susceptibility to perforin-granzyme, Anticancer Res, vol.29, pp.2137-4619528474, 2009. ,
Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate, ACS Chemical Biology, vol.7, issue.11, pp.1848-57, 2012. ,
DOI : 10.1021/cb3002478
URL : https://doi.org/10.1021/cb3002478
Lipoplex mediated silencing of membrane regulators (CD46, CD55 and CD59) enhances complement-dependent anti-tumor activity of trastuzumab and pertuzumab, Molecular Oncology, vol.150, issue.3, pp.580-94, 2013. ,
DOI : 10.1111/j.1365-2249.2007.03507.x
URL : https://doi.org/10.1016/j.molonc.2013.02.011
Antibody-dependent cellular cytotoxicity (ADCC) is mediated by genetically modified antigen-specific human T lymphocytes, Blood, vol.107, issue.12, pp.4669-77, 2006. ,
DOI : 10.1182/blood-2005-09-3775
A highly sensitive cytotoxicity assay based on the release of reporter enzymes, from stably transfected cell lines, J Immunol Methods, vol.20497, pp.89-98, 1997. ,
Reporter Enzyme Inhibitor Study To Aid Assembly of Orthogonal Reporter Gene Assays, ACS Chemical Biology, vol.8, issue.5, pp.1009-1026, 2013. ,
DOI : 10.1021/cb3007264
A novel ultrasensitive bioluminescent receptor-binding assay of INSL3 through chemical conjugation with nanoluciferase, Biochimie, vol.95, issue.12, pp.2454-2463, 2013. ,
DOI : 10.1016/j.biochi.2013.09.008
NanoLuc Reporter for Dual Luciferase Imaging in Living Animals, Molecular Imaging, vol.12, issue.7, pp.1-1324371848, 2013. ,
DOI : 10.2310/7290.2013.00062
URL : https://doi.org/10.2310/7290.2013.00062
Highly Sensitive Real-Time In Vivo Imaging of an Influenza Reporter Virus Reveals Dynamics of Replication and Spread, Journal of Virology, vol.87, issue.24, pp.13321-902381, 2013. ,
DOI : 10.1128/JVI.02381-13
A convenient luminescence assay of ferroportin internalization to study its interaction with hepcidin, FEBS Journal, vol.43, issue.8, pp.1773-81, 2013. ,
DOI : 10.1007/s00726-011-1164-z
URL : http://onlinelibrary.wiley.com/doi/10.1111/febs.12192/pdf
A sensitive assay for the biosynthesis and secretion of MANF using NanoLuc activity, Biochemical and Biophysical Research Communications, vol.449, issue.4, pp.483-492, 2014. ,
DOI : 10.1016/j.bbrc.2014.05.031
Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack, Blood, vol.121, issue.14, pp.2659-68, 2013. ,
DOI : 10.1182/blood-2012-07-446146
URL : http://www.bloodjournal.org/content/bloodjournal/121/14/2659.full.pdf
Mechanisms of granule-dependent killing, Cell Death & Differentiation, vol.1996, issue.2, pp.251-62, 2007. ,
DOI : 10.1182/blood-2006-03-010348
URL : http://www.nature.com/cdd/journal/v15/n2/pdf/4402244a.pdf
unified approach for performing an analytical methods comparability study [Internet], p.15081, 2015. ,
Assessing parallelism prior to determining relative potency, PDA J Pharm Sci Technol, vol.59, pp.127-3715971545, 2005. ,
Enhanced Anti-tumor Effect of Trastuzumab in Combination with Cisplatin, Japanese Journal of Cancer Research, vol.36, issue.5, pp.574-81, 2002. ,
DOI : 10.1016/0090-8258(90)90099-7
URL : http://onlinelibrary.wiley.com/doi/10.1111/j.1349-7006.2002.tb01293.x/pdf
A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions, Proceedings of the National Academy of Sciences, vol.91, issue.6, pp.19063-19071, 2006. ,
DOI : 10.1038/sj.bjc.6601676
URL : http://www.pnas.org/content/103/50/19063.full.pdf
Effects of trastuzumab on epidermal growth factor receptor-dependent and -independent human colon cancer cells, International Journal of Cancer, vol.105, issue.2, pp.291-301, 2004. ,
DOI : 10.1002/ijc.11137
URL : http://onlinelibrary.wiley.com/doi/10.1002/ijc.11686/pdf
Cytotoxic effect of calcein acetoxymethyl ester on human tumor cell lines, Anti-Cancer Drugs, vol.6, issue.4, pp.578-857579562, 1995. ,
DOI : 10.1097/00001813-199508000-00011
A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact, Cell, vol.63, issue.2, pp.251-80092, 1990. ,
DOI : 10.1016/0092-8674(90)90158-B
Multiparameter RNA and codon optimization: A standardized tool to assess and enhance autologous mammalian gene expression, PLoS One, vol.6, 2011. ,
DOI : 10.1371/journal.pone.0017596
URL : https://doi.org/10.1371/journal.pone.0017596