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Generation of fluorescently labeled tracers – which features influence the translational potential?

Fijs van Leeuwen 1, * Bart Cornelissen 2 Federico Caobelli 3 Laura Evangelista 4 Latifa Rbah-Vidal 5 Silvana Vecchio 6 Catarina Xavier 7 Jacques Barbet 5 Marion de Jong 8
* Corresponding author
1 Interventional Molecular Imaging Laboratory [Leiden, the Netherlands]
2 CRUK/MRC - Department of Oncology [Oxford, UK]
3 Department of Nuclear Medicine [Basel, Switzerland]
4 Nuclear Medicine and Molecular Imaging Unit [Padua, Italy]
5 CRCINA-ÉQUIPE 14 - Endothelium Radiobiology and Targeting
CRCINA - Centre de Recherche en Cancérologie et Immunologie Nantes-Angers
6 Department of Advanced Biomedical Sciences [Naples, Italy]
7 ICMI - In vivo Cellular and Molecular Imaging Laboratory [Brussel, Belgium]
8 Department of Radiology & Nuclear Medicine [Rotterdam, the Netherlands]
Abstract : Given the increasing exploration of fluorescent tracers in the field of nuclear medicine, a need has risen for practical development guidelines that can help improve the translation aspects of fluorescent tracers. This editorial discusses the does and don'ts in developing fluorescence tracers. It has been put forward by the European Association of Nuclear Medicine (EANM) Translational Molecular Imaging & Therapy committee and has been approved by the EANM board.
Keywords : Dual-modality Nuclear medicine Fluorescence Image guided surgery Molecular imaging Tracers
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https://www.hal.inserm.fr/inserm-01782195
Contributor : Elizabeth Bernardo <>
Submitted on : Tuesday, May 1, 2018 - 12:27:13 PM
Last modification on : Thursday, June 18, 2020 - 10:02:07 PM

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Fijs van Leeuwen, Bart Cornelissen, Federico Caobelli, Laura Evangelista, Latifa Rbah-Vidal, et al.. Generation of fluorescently labeled tracers – which features influence the translational potential?. European Association of Nuclear Medicine, issuing body - EJNMMI radiopharmacy and chemistry, London : Springer Open, [2016]-, 2017, 2 (1), pp.15. ⟨10.1186/s41181-017-0034-8⟩. ⟨inserm-01782195⟩

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