P. , I. Mav, J. Lcu, . Eb, . Th et al., Data analysis: VV, LCo. Data interpretation Drafting of the manuscript: VV, LCo. Critical review of the final version of the manuscript, Authors' contributions Literature search: LCo, VV. Study design: LCo All authors read and approved the final manuscript

. Dr, Janssen, MSD and ViiV Healthcare and non-financial support from Abbvie, Gilead Sciences, Janssen and MSD, outside the submitted work. Dr. Cabié reports non-financial support from BMS, Gilead Sciences and Janssen, outside the submitted work. Dr Cotte reports grants from ViiV Healthcare and MSD, personal fees from Abbvie ViiV Healthcare and non-financial support from Abbvie, Jacomet reports personal fees from Convergence Edition, Gilead Sciences and ViiV Healthcare, outside the submitted work. Dr. Pugliese, Dr Hustache-Mathieu, and Dr. Hoen have no conflicts of interest to disclose

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