S. Polager and D. Ginsberg, p53 and E2f: partners in life and death, Nature Reviews Cancer, vol.416, issue.10, pp.738-748, 2009.
DOI : 10.1038/msb.2008.65

J. Chipuk, J. Fisher, C. Dillon, R. Kriwacki, T. Kuwana et al., Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins, Proceedings of the National Academy of Sciences, vol.24, issue.5, pp.20327-20332, 2008.
DOI : 10.1016/j.molcel.2006.10.014

J. Martinou and R. Youle, Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics, Developmental Cell, vol.21, issue.1, pp.92-101, 2011.
DOI : 10.1016/j.devcel.2011.06.017

URL : https://doi.org/10.1016/j.devcel.2011.06.017

S. Tait and D. Green, Cell survival in tough times: The mitochondrial recovery plan, Cell Cycle, vol.9, issue.21, pp.4254-4255, 2010.
DOI : 10.4161/cc.9.21.13962

P. Juin, O. Geneste, F. Gautier, S. Depil, and M. Campone, Decoding and unlocking the BCL-2 dependency of cancer cells, Nature Reviews Cancer, vol.83, issue.7, pp.455-465, 2013.
DOI : 10.1016/j.bcp.2011.10.008

N. Marchenko, A. Zaika, and U. Moll, Death Signal-induced Localization of p53 Protein to Mitochondria, Journal of Biological Chemistry, vol.53, issue.3, pp.16202-16212, 2000.
DOI : 10.1093/emboj/18.21.6027

M. Mihara, S. Erster, A. Zaika, O. Petrenko, T. Chittenden et al., p53 Has a Direct Apoptogenic Role at the Mitochondria, Molecular Cell, vol.11, issue.3, pp.577-590, 2003.
DOI : 10.1016/S1097-2765(03)00050-9

J. Chipuk, T. Kuwana, L. Bouchier-hayes, N. Droin, D. Newmeyer et al., Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis, Science, vol.303, issue.5660, pp.1010-1014, 2004.
DOI : 10.1126/science.1092734

L. Pen, J. Laurent, M. Sarosiek, K. Vuillier, C. Gautier et al., Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL, Cell Death and Disease, vol.11, issue.2, p.2083, 2016.
DOI : 10.1093/nar/29.9.e45

URL : https://hal.archives-ouvertes.fr/inserm-01333971

J. Lindsay, M. Esposti, and A. Gilmore, Bcl-2 proteins and mitochondria???Specificity in membrane targeting for death, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1813, issue.4, pp.532-539, 2011.
DOI : 10.1016/j.bbamcr.2010.10.017

URL : https://doi.org/10.1016/j.bbamcr.2010.10.017

J. Montero, K. Sarosiek, J. Deangelo, O. Maertens, J. Ryan et al., Drug-Induced Death Signaling Strategy Rapidly Predicts Cancer Response to Chemotherapy, Cell, vol.160, issue.5, pp.977-989, 2015.
DOI : 10.1016/j.cell.2015.01.042

URL : https://doi.org/10.1016/j.cell.2015.01.042

F. Todt, Z. Cakir, F. Reichenbach, F. Emschermann, J. Lauterwasser et al., Differential retrotranslocation of mitochondrial Bax and Bak, The EMBO Journal, vol.34, issue.1, pp.67-80, 2015.
DOI : 10.15252/embj.201488806

F. Edlich, S. Banerjee, M. Suzuki, M. Cleland, D. Arnoult et al., Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol, Cell, vol.145, issue.1, pp.104-116, 2011.
DOI : 10.1016/j.cell.2011.02.034

J. Lauterwasser, F. Todt, R. Zerbes, T. Nguyen, W. Craigen et al., The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation, Scientific Reports, vol.199, issue.257, p.32994, 2016.
DOI : 10.1016/0003-2697(91)90094-A

B. Schellenberg, P. Wang, J. Keeble, R. Rodriguez-enriquez, S. Walker et al., Bax Exists in a Dynamic Equilibrium between the Cytosol and Mitochondria to Control Apoptotic Priming, Molecular Cell, vol.49, issue.5, pp.959-971, 2013.
DOI : 10.1016/j.molcel.2012.12.022

C. Vuillier, BCL-xL interaction triggers apoptosis EMBO reports amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737, Cell Death Differ, vol.20, pp.755-764

P. Roworth, A. Ghari, F. , L. Thangue, and N. , To live or let die ??? complexity within the E2F1 pathway, Molecular & Cellular Oncology, vol.11, issue.1, p.970480, 2015.
DOI : 10.1074/jbc.M704757200

J. Hsieh, S. Fredersdorf, T. Kouzarides, K. Martin, and X. Lu, E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction., Genes & Development, vol.11, issue.14, 1997.
DOI : 10.1101/gad.11.14.1840

A. Phillips, S. Bates, K. Ryan, K. Helin, and K. Vousden, Induction of DNA synthesis and apoptosis are separable functions of E2F-1., Genes & Development, vol.11, issue.14, pp.1853-1863, 1997.
DOI : 10.1101/gad.11.14.1853

K. Hilgendorf, E. Leshchiner, S. Nedelcu, M. Maynard, E. Calo et al., The retinoblastoma protein induces apoptosis directly at the mitochondria, Genes & Development, vol.27, issue.9, pp.1003-1015, 2013.
DOI : 10.1101/gad.211326.112

URL : http://genesdev.cshlp.org/content/27/9/1003.full.pdf

S. Tait, M. Parsons, F. Llambi, L. Bouchier-hayes, S. Connell et al., Resistance to Caspase-Independent Cell Death Requires Persistence of Intact Mitochondria, Developmental Cell, vol.18, issue.5, pp.802-813, 2010.
DOI : 10.1016/j.devcel.2010.03.014

H. Hao, C. Chen, X. Rao, J. Gomez-gutierrez, H. Zhou et al., E2F-1- and E2Ftr-mediated apoptosis: the role of DREAM and HRK, Journal of Cellular and Molecular Medicine, vol.86, issue.3, pp.605-615, 2012.
DOI : 10.1111/j.1755-148X.2008.00495.x

L. Bell, O. Prey, J. Ryan, and K. , DNA-binding independent cell death from a minimal proapoptotic region of E2F-1, Oncogene, vol.25, issue.41, pp.5656-5663, 2006.
DOI : 10.1093/nar/19.9.2499

J. Ding, B. Mooers, Z. Zhang, J. Kale, D. Falcone et al., After Embedding in Membranes Antiapoptotic Bcl-XL Protein Binds Both Bcl-2 Homology Region 3 and Helix 1 of Proapoptotic Bax Protein to Inhibit Apoptotic Mitochondrial Permeabilization, Journal of Biological Chemistry, vol.78, issue.17, pp.11873-11896, 2014.
DOI : 10.1074/jbc.M111.264481

J. Cartier, J. Berthelet, A. Marivin, S. Gemble, V. Edmond et al., Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription, Journal of Biological Chemistry, vol.30, issue.30, pp.26406-26417, 2011.
DOI : 10.1023/B:JOMG.0000023591.45568.77

F. Hagn, C. Klein, O. Demmer, N. Marchenko, A. Vaseva et al., BclxL Changes Conformation upon Binding to Wild-type but Not Mutant p53 DNA Binding Domain, Journal of Biological Chemistry, vol.14, issue.5, pp.3439-3450, 2010.
DOI : 10.1093/jac/20.5.639

URL : http://www.jbc.org/content/285/5/3439.full.pdf

J. Han, L. Goldstein, W. Hou, B. Gastman, and H. Rabinowich, Regulation of Mitochondrial Apoptotic Events by p53-mediated Disruption of Complexes between Antiapoptotic Bcl-2 Members and Bim, Journal of Biological Chemistry, vol.8, issue.29, pp.22473-22483, 2010.
DOI : 10.1074/jbc.M611186200

F. Todt, Z. Cakir, F. Reichenbach, R. Youle, and F. Edlich, The C-terminal helix of Bcl-xL mediates Bax retrotranslocation from the mitochondria, Cell Death & Differentiation, vol.31, issue.2, pp.333-342, 2013.
DOI : 10.1038/onc.2011.497

J. Pécot, L. Maillet, L. Pen, J. Vuillier, C. Trécesson et al., Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance, Cell Reports, vol.17, issue.12, pp.3347-3358, 2016.
DOI : 10.1016/j.celrep.2016.11.064

S. Xu, G. Peng, Y. Wang, S. Fang, and M. Karbowski, The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover, Molecular Biology of the Cell, vol.22, issue.3, pp.291-300, 2011.
DOI : 10.1091/mbc.E10-09-0748

URL : http://www.molbiolcell.org/content/22/3/291.full.pdf

Y. Hsu, K. Wolter, and R. Youle, Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis, Proceedings of the National Academy of Sciences, vol.92, issue.10, pp.3668-3672, 1997.
DOI : 10.1073/pnas.92.10.4507

F. Gautier, Y. Guillemin, P. Cartron, T. Gallenne, N. Cauquil et al., Bax Activation by Engagement with, Then Release from, the BH3 Binding Site of Bcl-xL, Molecular and Cellular Biology, vol.31, issue.4, pp.832-844, 2011.
DOI : 10.1128/MCB.00161-10