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biospear: an R package for biomarker selection in penalized Cox regression.

Nils Ternes 1, 2 Federico Rotolo 1, 2 Stefan Michiels 2, 1, *
* Corresponding author
2 U1018 (Équipe 2) - Méthodologie et épidémiologie clinique en oncologie moléculaire
CESP - Centre de recherche en épidémiologie et santé des populations, IGR - Institut Gustave Roussy
Abstract : Summary: The R package biospear allows selecting the biomarkers with the strongest impact on survival and on the treatment effect in high-dimensional Cox models, and estimating expected survival probabilities. Most of the implemented approaches are based on penalized regression techniques. Availability: The package is available on the CRAN. ( ).
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Submitted on : Tuesday, November 7, 2017 - 10:53:45 AM
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Nils Ternes, Federico Rotolo, Stefan Michiels. biospear: an R package for biomarker selection in penalized Cox regression.. Bioinformatics, Oxford University Press (OUP), 2017, Epub ahead of print. ⟨10.1093/bioinformatics/btx560⟩. ⟨inserm-01630061⟩



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