Decoding and unlocking the BCL-2 dependency of cancer cells, Nature Reviews Cancer, vol.83, issue.7, pp.455-465, 2013. ,
DOI : 10.1016/j.bcp.2011.10.008
An informatics approach identifying markers of chemosensitivity in human cancer cell lines, Cancer Res, vol.60, pp.6101-6110, 2000. ,
Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency, Cancer Cell, vol.21, issue.4, pp.547-562, 2012. ,
DOI : 10.1016/j.ccr.2012.02.028
Programmed Anuclear Cell Death Delimits Platelet Life Span, Cell, vol.128, issue.6, pp.1173-1186, 2007. ,
DOI : 10.1016/j.cell.2007.01.037
URL : https://doi.org/10.1016/j.cell.2007.01.037
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release, Genes & Development, vol.13, issue.11, pp.1367-1381, 1999. ,
DOI : 10.1101/gad.13.11.1367
URL : http://genesdev.cshlp.org/content/13/11/1367.full.pdf
Intrinsic tumour suppression, Nature, vol.35, issue.7015, pp.307-315, 2004. ,
DOI : 10.1016/S0962-8924(01)02151-1
RAS oncogenes: weaving a tumorigenic web, Nature Reviews Cancer, vol.410, issue.11, pp.761-774, 2011. ,
DOI : 10.1038/35074129
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632399/pdf
Targeting RAS signalling pathways in cancer therapy, Nature Reviews Cancer, vol.61, issue.1, pp.11-22, 2003. ,
DOI : 10.1038/356397a0
A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors, BMC Medical Genomics, vol.98, issue.Suppl 1, p.26, 2010. ,
DOI : 10.1093/jnci/djj052
Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival, Cell Cycle, vol.31, issue.18, pp.2937-2947, 2013. ,
DOI : 10.1146/annurev-immunol-032712-100008
URL : http://www.tandfonline.com/doi/pdf/10.4161/cc.25972?needAccess=true
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells, Cell, vol.133, issue.4, pp.704-715, 2008. ,
DOI : 10.1016/j.cell.2008.03.027
Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition, PLoS ONE, vol.133, issue.8, p.2888, 2008. ,
DOI : 10.1371/journal.pone.0002888.g005
Cancer stem cells: Implications for cancer causation and therapy resistance, Discov. Med, vol.5, pp.278-282, 2005. ,
Cancer Stem Cells and Radiotherapy: New Insights Into Tumor Radioresistance, JNCI: Journal of the National Cancer Institute, vol.98, issue.24, pp.1755-1757, 2006. ,
DOI : 10.1093/jnci/djj505
URL : https://academic.oup.com/jnci/article-pdf/98/24/1755/7688244/djj505.pdf
Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras Mediated Transformation, Cancer Research, vol.67, issue.18, pp.8460-8467, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-0108
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion, Proceedings of the National Academy of Sciences, vol.17, issue.10, pp.1397-1402, 2011. ,
DOI : 10.1101/gad.1061803
Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation, Proteome Science, vol.6, issue.1, p.27, 2008. ,
DOI : 10.1186/1477-5956-6-27
URL : https://proteomesci.biomedcentral.com/track/pdf/10.1186/1477-5956-6-27?site=proteomesci.biomedcentral.com
Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression, Cell, vol.135, issue.2, pp.227-239, 2008. ,
DOI : 10.1016/j.cell.2008.09.017
URL : https://doi.org/10.1016/j.cell.2008.09.017
HMGA2 Maintains Oncogenic RAS-Induced Epithelial-Mesenchymal Transition in Human Pancreatic Cancer Cells, The American Journal of Pathology, vol.174, issue.3, pp.854-868, 2009. ,
DOI : 10.2353/ajpath.2009.080523
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665746/pdf
HMGA2 Is a Driver of Tumor Metastasis, Cancer Research, vol.73, issue.14, pp.4289-4299, 2013. ,
DOI : 10.1158/0008-5472.CAN-12-3848
Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals, Molecular Cell, vol.49, issue.2, pp.249-261, 2013. ,
DOI : 10.1016/j.molcel.2012.11.002
Protein Kinase C ?? Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells, Cancer Cell, vol.24, issue.3, pp.347-364, 2013. ,
DOI : 10.1016/j.ccr.2013.08.005
URL : https://doi.org/10.1016/j.ccr.2013.08.005
Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models, Cancer Cell, vol.23, issue.1, pp.121-128, 2013. ,
DOI : 10.1016/j.ccr.2012.11.007
Ubiquitin on Ras: Warden or Partner in Crime?, Science Signaling, vol.4, issue.163, p.12, 2011. ,
DOI : 10.1126/scisignal.2001874
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495660/pdf
Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells, Nature, vol.29, issue.7571, pp.131-135, 2015. ,
DOI : 10.1093/bioinformatics/bts714
BCL-XL Mediates the Strong Selective Advantage of a 20q11.21 Amplification Commonly Found in Human Embryonic Stem Cell Cultures, Stem Cell Reports, vol.1, issue.5, pp.379-386, 2013. ,
DOI : 10.1016/j.stemcr.2013.10.005
Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL, MHR: Basic science of reproductive medicine, vol.20, issue.2, pp.168-177, 2014. ,
DOI : 10.1093/molehr/gat077
PKC Regulates a Farnesyl-Electrostatic Switch on K-Ras that Promotes its Association with Bcl-Xl on Mitochondria and Induces Apoptosis, Molecular Cell, vol.21, issue.4, pp.481-493, 2006. ,
DOI : 10.1016/j.molcel.2006.01.012
URL : https://doi.org/10.1016/j.molcel.2006.01.012
RelB NF-??B Represses Estrogen Receptor ?? Expression via Induction of the Zinc Finger Protein Blimp1, Molecular and Cellular Biology, vol.29, issue.14, pp.3832-3844, 2009. ,
DOI : 10.1128/MCB.00032-09
A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Research, vol.29, issue.9, p.45, 2001. ,
DOI : 10.1093/nar/29.9.e45
Accurate normalization of real-time quantitative RT- PCR data by geometric averaging of multiple internal control genes, Genome. Biol, vol.3, p.34, 2002. ,