L. Musset, S. Pelleau, and R. Girod, Malaria on the Guiana Shield: a review of the situation in French 363

H. Hiwat, L. Hardjopawiro, and W. Takken, Novel strategies lead to pre-elimination of malaria in previously high-risk areas in Suriname, South America, Malaria Journal, vol.11, issue.1, pp.10-366, 2012.
DOI : 10.3201/eid1302.060631

V. Ardillon, F. Eltges, and A. Chocho, Evolution de la situation épidémiologique du paludisme en 367

. Guyane-de, Bull Veille Sanit -Cire Antill-Guyane, pp.5-11, 2005.

L. Préfecture-de and . Guyane, Lutte contre l'orpaillage illégal en Guyane. 369 http://www.guyane.pref.gouv.fr/Publications/Etudes-sur-la-Guyane/Lutte-contre-l-orpaillage- 370 illegale-Bilan-et-actions, pp.28-29, 2014.

M. Douine, L. Musset, and F. Corlin, Prevalence of Plasmodium spp. in illegal gold miners in French Guiana in 2015: a hidden but critical malaria reservoir, 373 7. Pommier de Santi V, Djossou FCL, Barthes N, et al. Malaria Hyperendemicity and Risk for 374, p.315, 2016.
DOI : 10.1371/journal.pone.0103905

URL : https://hal.archives-ouvertes.fr/hal-01346800

M. Heemskerk and C. Duijves, Study on the knowledge, attitudes and practices of malaria and malaria 377 treatment in the small-scale gold mining sector in Suriname. 2013. 378 http://siapsprogram.org/publication/study-on-the-knowledge-attitudes-and-practices-of-malaria- 379 and-malaria-treatment-in-the-small-scale-gold-mining-sector-in-suriname

M. Gatton, L. Martin, and Q. Cheng, Evolution of Resistance to Sulfadoxine-Pyrimethamine in 381

N. White, Antimalarial drug resistance, Journal of Clinical Investigation, vol.113, issue.8, pp.1084-92, 2004.
DOI : 10.1172/JCI21682

R. Packard, The Origins of Antimalarial-Drug Resistance, New England Journal of Medicine, vol.371, issue.5, pp.397-406, 2014.
DOI : 10.1056/NEJMp1403340

D. 'alessandro, U. Buttiens, and H. , History and importance of antimalarial drug resistance, Tropical Medicine and International Health, vol.41, issue.11, pp.845-853, 2001.
DOI : 10.1016/0169-4758(96)10055-7

P. Phompradit, P. Muhamad, and R. Wisedpanichkij, Four years' monitoring of in vitro sensitivity 387 and candidate molecular markers of resistance of Plasmodium falciparum to artesunate- 388 mefloquine combination in the Thai-Myanmar border Artemisinin resistance in Plasmodium falciparum malaria, Malar J. N Engl J Med, vol.13, issue.361, pp.455-67, 2009.

E. Ashley, M. Dhorda, and R. Fairhurst, Malaria, New England Journal of Medicine, vol.371, issue.5, pp.411-434, 2014.
DOI : 10.1056/NEJMoa1314981

URL : https://hal.archives-ouvertes.fr/inserm-00854378

K. Wangdi, M. Gatton, and G. Kelly, Cross-Border Malaria: A Major Obstacle for Malaria Elimination, Adv Parasitol, vol.89, pp.79-107, 2015.
DOI : 10.1016/bs.apar.2015.04.002

R. Fairhurst, G. Nayyar, and J. Breman, Artemisinin-Resistant Malaria: Research Challenges, Opportunities, and Public Health Implications, The American Journal of Tropical Medicine and Hygiene, vol.87, issue.2, pp.231-272, 2012.
DOI : 10.4269/ajtmh.2012.12-0025

URL : http://www.ajtmh.org/deliver/fulltext/14761645/87/2/231.pdf?itemId=/content/journals/10.4269/ajtmh.2012.12-0025&mimeType=pdf&containerItemId=content/journals/14761645

B. Witkowski, C. Amaratunga, and N. Khim, Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies, The Lancet Infectious Diseases, vol.13, issue.12, pp.1043-1052, 2013.
DOI : 10.1016/S1473-3099(13)70252-4

URL : https://hal.archives-ouvertes.fr/pasteur-00863935

F. Ariey, B. Witkowski, and C. Amaratunga, A molecular marker of artemisinin-resistant Plasmodium falciparum malaria, Nature, vol.10, issue.7481, pp.50-55, 2014.
DOI : 10.1038/nsb899

URL : https://hal.archives-ouvertes.fr/pasteur-00921203

L. Bras, J. Deloron, P. Ricour, and A. , Plasmodium falciparum: Drug sensitivity in vitro of isolates before and after adaptation to continuous culture, Experimental Parasitology, vol.56, issue.1, pp.9-14, 1983.
DOI : 10.1016/0014-4894(83)90091-7

F. Breeveld, S. Vreden, and M. Grobusch, History of malaria research and its contribution to the malaria control success in Suriname: a review, Malaria Journal, vol.11, issue.1, pp.95-406, 2012.
DOI : 10.1016/j.socscimed.2004.05.025

P. Wilairatana, S. Krudsood, and K. Chalermrut, An open randomized clinical trial of Artecom vs 407 artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand. 408 Southeast Asian, J Trop Med Public Health, vol.33, pp.519-543, 2002.

H. Menan, O. Faye, and A. Same-ekobo, Comparative study of the efficacy and tolerability of 410 dihydroartemisinin-piperaquine-trimethoprim versus artemether-lumefantrine in the treatment of 411 uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal, Malar J, vol.412, issue.10, pp.185-413, 2011.

L. Evans, V. Coignez, and A. Barojas, Quality of anti-malarials collected in the private and informal sectors in Guyana and Suriname, Malaria Journal, vol.11, issue.1, pp.203-415, 2012.
DOI : 10.1186/1475-2875-4-28

V. Pribluda, L. Evans, and E. Barillas, Were medicine quality and pharmaceutical management 416 contributing factors in diminishing artemisinin efficacy in Guyana and Suriname?, Malar J, vol.417, pp.1377-418, 2014.

A. Yakasai, M. Hamza, and M. Dalhat, Adherence to Artemisinin-Based Combination Therapy for 419 the Treatment of Uncomplicated Malaria: A Systematic Review and Meta-Analysis, J Trop Med, vol.420, issue.2015, pp.189232-421, 2015.

S. Yeung and N. White, How do patients use antimalarial drugs? A review of the evidence, Tropical Medicine and International Health, vol.6, issue.1, pp.121-159, 2005.
DOI : 10.1046/j.1365-3156.1999.00471.x

C. Osorio-de-castro, M. Suárez-mutis, and E. Miranda, Dispensing and determinants of non- 424 adherence to treatment for non complicated malaria caused by Plasmodium vivax and Plasmodium 425 falciparum in high-risk municipalities in the Brazilian Amazon, Malar J, vol.14, p.426, 2015.

K. Bruxvoort, C. Festo, and M. Cairns, Measuring Patient Adherence to Malaria Treatment: A Comparison of Results from Self-Report and a Customised Electronic Monitoring Device, PLOS ONE, vol.60, issue.6, pp.134275-429, 2015.
DOI : 10.1371/journal.pone.0134275.s002

J. Amon, T. Brown, and J. Hogle, Behavioral Surveillance Surveys, BSS. Guidelines for repeated 430 behavioral surveys in populations at risk of HIV

I. Saran, E. Yavuz, and H. Kasozi, Can rapid diagnostic testing for malaria increase adherence to 433 artemether-lumefantrine?: A randomized controlled trial in Uganda, Am J Trop Med Hyg, vol.434, pp.94857-67, 2016.

L. Tourneau and F. , Les orpailleurs clandestins de Guyane française. Premier rapport d'étape dans 436 l'étude FAG/CNRS. CNRS, 2016.

S. Chenet, A. Okoth, S. Huber, and C. , Kelch Propeller Domain Mutant Allele C580Y in Guyana, Journal of Infectious Diseases, vol.213, issue.9, pp.1472-1477, 2016.
DOI : 10.1093/infdis/jiv752

URL : https://academic.oup.com/jid/article-pdf/213/9/1472/17411294/jiv752.pdf

D. Ménard, N. Khim, and J. Beghain, A Worldwide Map of Plasmodium falciparum K13-Propeller 440

I. Hastings, Complex dynamics and stability of resistance to antimalarial drugs, Parasitology, vol.62, issue.05, pp.615-639, 2006.
DOI : 10.1086/342946

Y. Lubell, A. Dondorp, and P. Guerin, Artemisinin resistance ??? modelling the potential human and economic costs, Malaria Journal, vol.13, issue.1, pp.452-445, 2014.
DOI : 10.1016/S0140-6736(12)60034-8

URL : http://doi.org/10.1186/1475-2875-13-452