P. Silva, A. Trifunovic, P. Navas, J. Vazquez, and J. A. Enríquez, The 7, 2016.
URL : https://hal.archives-ouvertes.fr/in2p3-00680507

S. Guerrero-castillo, F. Baertling, D. Kownatzki, and H. J. Wessels, The Assembly Pathway of Mitochondrial Respiratory 11

L. Brizuela, J. A. Pospisilik, L. E. Otterbein, and O. Wagner, The 15, 2012.

L. He, K. J. Weber, and J. D. Schilling, Glutamine modulates macrophage 19 lipotoxicity, 2016.

I. J. Clifton, D. Butler, A. S. Soares, N. J. Oldham, L. A. Mcneill et al., Structural and mechanistic studies on the inhibition of the hypoxia bacterial endotoxin and cytokines, Biol. Chem, vol.23, issue.398, pp.303-317, 2007.

A. Iwasaki and R. Medzhitov, Regulation of adaptive immunity by the innate 3, 2010.

F. S. Sutterwala, Mitochondrial cardiolipin is required for Nlrp3 7, 2013.

C. A. Janeway, Approaching the asymptote? Evolution and revolution in 10 immunology, Cold Spring Harbor Symposia on Quantitative Biology, 1989.

Z. Jin, W. Wei, M. Yang, Y. Du, and Y. Wan, Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization, Cell Metabolism, vol.20, issue.3, pp.483-498, 2014.
DOI : 10.1016/j.cmet.2014.07.011

R. Van-crevel and M. G. Netea, Rewiring cellular metabolism via the 22, 2016.

E. L. Mills, B. Kelly, and L. A. O-'neill, Mitochondria are the powerhouses of immunity, Nature Immunology, vol.118, issue.5, pp.488-498, 2017.
DOI : 10.7150/ijbs.14405

J. Howrylak, S. W. Ryter, K. Nakahira, and A. M. Choi, UCP2-induced fatty 16 acid synthase promotes NLRP3 inflammasome activation during sepsis, J Clin, vol.17, 2015.

J. S. Moon, K. Nakahira, K. P. Chung, G. M. Denicola, M. J. Koo et al., NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages, Nature Medicine, vol.21, issue.9, pp.1002-1012, 2016.
DOI : 10.1038/ni.1980

A. Mourier, S. Matic, B. Ruzzenente, N. G. Larsson, and D. Milenkovic, The 23 respiratory Chain supercomplex organization is independent of COX7A2L, 2014.

D. Namgaladze and B. Brüne, Fatty acid oxidation is dispensable for human 1, 2014.

L. A. Oneill and R. J. Xavier, Trained immunity: A program of innate 14 immune memory in health and disease, Science, vol.352, issue.80, pp.1098-1098, 2016.

P. Newsholme, R. Curi, S. Gordon, and E. A. Newsholme, Metabolism of glucose, 17 glutamine, long-chain fatty acids and ketone bodies by murine macrophages, 1986.

M. Nomura, J. Liu, I. I. Rovira, E. Gonzalez-hurtado, J. Lee et al., Fatty acid oxidation in macrophage polarization, Nature Immunology, vol.332, issue.3, pp.216-217, 2016.
DOI : 10.1126/science.1204351

O. Neill, L. A. Kishton, R. J. Rathmell, and J. , A guide to immunometabolism for 23 immunologists, Nat Rev Immunol, vol.16, 2016.

S. Rousset, Y. Emre, O. Join-lambert, C. Hurtaud, and D. Ricquier, The uncoupling protein 2 modulates the cytokine balance in innate immunity???, Cytokine, vol.35, issue.3-4, pp.135-142
DOI : 10.1016/j.cyto.2006.07.012

URL : https://hal.archives-ouvertes.fr/hal-00136168

J. Swanson, M. Müller, and J. M. Blander, Sensing prokaryotic mRNA 20 signifies microbial viability and promotes immunity, Nature, vol.474, pp.385-389, 2012.

A. J. Sbarra and M. L. Karnovsky, The biochemical basis of phagocytosis, p.23, 1960.

G. Jiménez, E. Toledano, V. Cubillos-zapata, C. Rapisarda, A. Chen et al., Incorporation of C14-labeled building blocks into lipid, protein

S. K. Biswas, Human monocytes undergo functional re-programming 3, 2015.

D. Speijer, Being right on Q: shaping eukaryotic evolution A kinetic theory in 11 which FADH 2 /NADH ratios determine mitochondrial ROS formation, pp.10-1042, 2016.

D. Speijer, Oxygen radicals shaping evolution: Why fatty acid catabolism leads to peroxisomes while neurons do without it, BioEssays, vol.12, issue.2, pp.88-94, 2011.
DOI : 10.1016/j.cmet.2010.08.002

F. Stavru, A. E. Palmer, C. Wang, R. J. Youle, and P. Cossart, Atypical 22 mitochondrial fission upon bacterial infection, Proc. Natl. Acad. Sci. U. S. A, vol.23, issue.110, pp.16003-16011, 2013.

J. A. Smeitink and L. G. Nijtmans, Cytosolic signaling protein Ecsit also 5 localizes to mitochondria where it interacts with chaperone NDUFAF1 and 6 functions in complex I assembly, Genes Dev, vol.21, pp.615-624, 2007.

C. Wallace and D. Keast, Glutamine and macrophage function, Metabolism, vol.41, issue.9, p.9, 1992.
DOI : 10.1016/0026-0495(92)90130-3

J. R. Means, R. E. Iwasaki, A. Shadel, and G. S. , Mitochondrial DNA stress 17 primes the antiviral innate immune response, Nature, vol.520, pp.553-560, 2015.

A. P. West, G. S. Shadel, and S. Ghosh, Mitochondria in innate immune responses, Nature Reviews Immunology, vol.278, issue.6, pp.389-402, 2011.
DOI : 10.1074/jbc.M210269200