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Intraoperative Functional Ultrasound Imaging of Human Brain Activity.

Abstract : The functional mapping of brain activity is essential to perform optimal glioma surgery and to minimize the risk of postoperative deficits. We introduce a new, portable neuroimaging modality of the human brain based on functional ultrasound (fUS) for deep functional cortical mapping. Using plane-wave transmissions at an ultrafast frame rate (1 kHz), fUS is performed during surgery to measure transient changes in cerebral blood volume with a high spatiotemporal resolution (250 µm, 1 ms). fUS identifies, maps and differentiates regions of brain activation during task-evoked cortical responses within the depth of a sulcus in both awake and anaesthetized patients.
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Contributor : Marion Imbault <>
Submitted on : Tuesday, September 19, 2017 - 8:27:15 PM
Last modification on : Sunday, April 25, 2021 - 1:42:02 PM


  • HAL Id : inserm-01590634, version 1
  • PUBMED : 28779069


Marion Imbault, Dorian Chauvet, Jean-Luc Gennisson, Laurent Capelle, Mickael Tanter. Intraoperative Functional Ultrasound Imaging of Human Brain Activity.. Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.7304. ⟨inserm-01590634⟩



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