C. Latham, S. Osborne, M. Cryle, and F. Meunier, Cellular prion protein; PS: Phosphatidylserine; PSD95: Postsynaptic density protein 95; PUFA: Polyunsaturated fatty acid; STD: Standard diet References 1 Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a, PI: Phosphatidylinositol; PrPc, pp.1543-54, 2007.
DOI : 10.1111/j.1471-4159.2006.04286.x

C. Rickman and B. Davletov, Arachidonic Acid Allows SNARE Complex Formation in the Presence of Munc18, Chemistry & Biology, vol.12, issue.5, pp.545-53, 2005.
DOI : 10.1016/j.chembiol.2005.03.004

B. Leu and J. Schmidt, Arachidonic acid as a retrograde signal controlling growth and dynamics of retinotectal arbors, Developmental Neurobiology, vol.395, issue.1, pp.18-30, 2008.
DOI : 10.1001/archopht.116.3.342

J. Schmidt, L. Mariconda, F. Morillo, and E. Apraku, A role for the polarity complex and PI3 kinase in branch formation within retinotectal arbors of zebrafish, Developmental Neurobiology, vol.361, issue.6, pp.591-601, 2014.
DOI : 10.1098/rstb.2006.1882

A. Breukel, E. Besselsen, F. L. Da-silva, and W. Ghijsen, Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals, Brain Research, vol.773, issue.1-2, pp.90-97, 1997.
DOI : 10.1016/S0006-8993(97)00918-9

T. Almeida, R. Cunha, and J. Ribeiro, Facilitation by arachidonic acid of acetylcholine release from the rat hippocampus, Brain Research, vol.826, issue.1, pp.104-115, 1999.
DOI : 10.1016/S0006-8993(99)01267-6

M. Carta, F. Lanore, N. Rebola, Z. Szabo, D. Silva et al., Membrane Lipids Tune Synaptic Transmission by Direct Modulation of Presynaptic Potassium Channels, Neuron, vol.81, issue.4, pp.787-99, 2014.
DOI : 10.1016/j.neuron.2013.12.028

URL : https://hal.archives-ouvertes.fr/hal-00993383

G. Czapski, K. Czubowicz, J. Strosznajder, and R. Strosznajder, The Lipoxygenases: Their Regulation and Implication in Alzheimer???s Disease, Neurochemical Research, vol.81, issue.2???3, pp.243-57, 2016.
DOI : 10.1016/j.plefa.2009.05.024

M. Figueiredo-pereira, P. Rockwell, T. Schmidt-glenewinkel, and P. Serrano, Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration, Frontiers in Molecular Neuroscience, vol.7, issue.369, p.104, 2014.
DOI : 10.1016/j.nurt.2009.10.016

J. Rao, M. Kellom, H. Kim, S. Rapoport, and E. Reese, Neuroinflammation and Synaptic Loss, Neurochemical Research, vol.11, issue.Suppl 1, pp.903-913, 2012.
DOI : 10.1038/sj.mp.4001792

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478877

N. Woodling, Q. Wang, P. Priyam, P. Larkin, J. Shi et al., Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling, Journal of Neuroscience, vol.34, issue.17, pp.5882-94, 2014.
DOI : 10.1523/JNEUROSCI.0410-14.2014

C. Leslie, Regulation of the specific release of arachidonic acid by cytosolic phospholipase A2, Prostaglandins, Leukotrienes and Essential Fatty Acids, vol.70, issue.4, pp.373-379, 2004.
DOI : 10.1016/j.plefa.2003.12.012

B. Kriem, I. Sponne, A. Fifre, C. Malaplate-armand, K. Lozac-'h-pillot et al., Cytosolic phospholipase A 2 mediates neuronal apoptosis induced by soluble oligomers of the amyloid-beta peptide, FASEB J, vol.19, pp.85-92, 2005.

R. Sanchez-mejia, J. Newman, S. Toh, G. Yu, Y. Zhou et al., Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease, Nature Neuroscience, vol.3, issue.6, pp.1311-1319, 2008.
DOI : 10.1038/nn.2213

C. Desbène, C. Malaplate-armand, I. Youssef, P. Garcia, C. Stenger et al., Critical role of cPLA 2 in A? oligomer-induced neurodegeneration and memory deficit, Neurobiol Aging, vol.33, pp.1123-1140, 2012.

W. Lands, Metabolism of glycerolipides; a comparison of lecithin and triglyceride synthesis, J Biol Chem, vol.231, pp.883-891, 1958.

Y. Cho, A novel role of brain-type ACS4 isotype in neuronal differentiation, Biochemical and Biophysical Research Communications, vol.419, issue.3, pp.505-515, 2012.
DOI : 10.1016/j.bbrc.2012.02.046

S. Ferreira, M. Lourenco, M. Oliveira, D. Felice, and F. , Soluble amyloid-? oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease, Front Cell Neurosci, vol.9, p.191, 2015.

L. Haas, S. Salazar, M. Kostylev, J. Um, A. Kaufman et al., Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer???s disease, Brain, vol.139, issue.2, pp.526-572, 2016.
DOI : 10.1093/brain/awv356

URL : http://doi.org/10.1093/brain/awv356

E. Pinnock, K. Jovanovic, M. Pinto, E. Ferreira, D. Costa et al., LRP/LR Antibody Mediated Rescuing of Amyloid-??-Induced Cytotoxicity is Dependent on PrPc in Alzheimer???s Disease, Journal of Alzheimer's Disease, vol.2, issue.3, pp.645-57, 2015.
DOI : 10.1038/ncomms1341

E. West, C. Osborne, W. Nolan, and C. Bate, Monoacylated Cellular Prion Proteins Reduce Amyloid-??-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage, Biology, vol.268, issue.2, pp.367-82, 2015.
DOI : 10.1126/science.1174621

S. Tu, S. Okamoto, S. Lipton, and H. Xu, Oligomeric A??-induced synaptic dysfunction in Alzheimer???s disease, Molecular Neurodegeneration, vol.9, issue.1, p.48, 2014.
DOI : 10.1093/hmg/dds072

D. Whitcomb, E. Hogg, P. Regan, T. Piers, P. Narayan et al., Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus, Scientific Reports, vol.125, issue.1, p.10934, 2015.
DOI : 10.1016/S0165-0270(03)00050-5

J. Henley and K. Wilkinson, AMPA receptor trafficking and the mechanisms underlying synaptic plasticity and cognitive aging, Dialogues Clin Neurosci, vol.15, pp.11-27, 2013.

I. Youssef, S. Florent-béchard, C. Malaplate-armand, V. Koziel, B. Bihain et al., N-truncated amyloid-?? oligomers induce learning impairment and neuronal apoptosis, Neurobiology of Aging, vol.29, issue.9, pp.1319-1352, 2008.
DOI : 10.1016/j.neurobiolaging.2007.03.005

P. Garcia, I. Youssef, J. Utvik, S. Florent-béchard, V. Barthélémy et al., Ciliary Neurotrophic Factor Cell-Based Delivery Prevents Synaptic Impairment and Improves Memory in Mouse Models of Alzheimer's Disease, Journal of Neuroscience, vol.30, issue.22, pp.7516-7543, 2010.
DOI : 10.1523/JNEUROSCI.4182-09.2010

R. Morris, Developments of a water-maze procedure for studying spatial learning in the rat, Journal of Neuroscience Methods, vol.11, issue.1, pp.47-60, 1984.
DOI : 10.1016/0165-0270(84)90007-4

J. Folch, M. Lees, S. Stanley, and G. , A simple method for the isolation and purification of total lipides from animal tissues, J Biol Chem, vol.226, pp.497-509, 1957.

G. Lepage and C. Roy, Direct transesterification of all classes of lipids in one-step reaction, J Lipid Res, vol.27, pp.114-134, 1986.

S. Uran, Å. Larsen, P. Jacobsen, and T. Skotland, Analysis of phospholipid species in human blood using normal-phase liquid chromatography coupled with electrospray ionization ion-trap tandem mass spectrometry, Journal of Chromatography B: Biomedical Sciences and Applications, vol.758, issue.2, pp.265-75, 2001.
DOI : 10.1016/S0378-4347(01)00188-8

C. Skeaff, L. Hodson, and J. Mckenzie, Dietary-induced changes in fatty acid composition of human plasma, platelet, and erythrocyte lipids follow a similar time course, J Nutr, vol.136, pp.565-574, 2006.

K. Lee, C. Moussa, Y. Lee, Y. Sung, B. Howell et al., Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines, Neuroscience, vol.169, issue.1, pp.344-56, 2010.
DOI : 10.1016/j.neuroscience.2010.04.078

E. Miller, P. Teravskis, B. Dummer, X. Zhao, R. Huganir et al., Tau phosphorylation and tau mislocalization mediate soluble A?? oligomer-induced AMPA glutamate receptor signaling deficits, European Journal of Neuroscience, vol.44, issue.Suppl 1, pp.1214-1238, 2014.
DOI : 10.1016/j.neuron.2004.11.011

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123852

D. Nair, E. Hosy, J. Petersen, A. Constals, G. Giannone et al., Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95, Journal of Neuroscience, vol.33, issue.32, pp.13204-13228, 2013.
DOI : 10.1523/JNEUROSCI.2381-12.2013

URL : http://www.jneurosci.org/content/jneuro/33/32/13204.full.pdf

F. Yaghmoor, A. Noorsaeed, S. Alsaggaf, W. Aljohani, H. Scholtzova et al., The Role of TREM2 in Alzheimer???s Disease and Other Neurological Disorders, Journal of Alzheimer's Disease & Parkinsonism, vol.04, issue.05, p.160, 2014.
DOI : 10.4172/2161-0460.1000160

Y. Lu, W. Liu, and X. Wang, TREM2 variants and risk of Alzheimer???s disease: a meta-analysis, Neurological Sciences, vol.71, issue.4, pp.1881-1889, 2015.
DOI : 10.1001/jamaneurol.2013.6237

G. Barceló-coblijn, E. Högyes, K. Kitajka, L. Puskás, A. Zvara et al., Modification by docosahexaenoic acid of age-induced alterations in gene expression and molecular composition of rat brain phospholipids, Proceedings of the National Academy of Sciences, vol.91, issue.18, pp.11321-11327, 2003.
DOI : 10.1073/pnas.91.18.8368

Y. Sato, F. Bernier, I. Suzuki, S. Kotani, M. Nakagawa et al., Comparative lipidomics of mouse brain exposed to enriched environment, Journal of Lipid Research, vol.2, issue.Suppl. 1, pp.2687-96, 2013.
DOI : 10.1038/srep00431

L. Horrocks, Sources for Brain Arachidonic Acid Uptake and Turnover in Glycerophospholipids, Annals of the New York Academy of Sciences, vol.261, issue.1 Arachidonie A, pp.17-24, 1989.
DOI : 10.1016/0006-291X(85)90162-7

T. Tanaka, D. Iwawaki, M. Sakamoto, Y. Takai, J. Morishige et al., Mechanisms of accumulation of arachidonate in phosphatidylinositol in yellowtail. A comparative study of acylation systems of phospholipids in rat and the fish species Seriola quinqueradiata, European Journal of Biochemistry, vol.86, issue.7, pp.1466-73, 2003.
DOI : 10.1038/16711

B. Sarkar, A. Das, and S. Maiti, Thermodynamically stable amyloid-?? monomers have much lower membrane affinity than the small oligomers, Frontiers in Physiology, vol.4, p.84, 2013.
DOI : 10.3389/fphys.2013.00084

URL : http://doi.org/10.3389/fphys.2013.00084

F. Morroni, G. Sita, A. Tarozzi, R. Rimondini, and P. Hrelia, Early effects of A?? 1-42 oligomers injection in mice: Involvement of PI3K/Akt/GSK3 and MAPK/ERK1/2 pathways, Behavioural Brain Research, vol.314, pp.106-121, 2016.
DOI : 10.1016/j.bbr.2016.08.002

F. Mcintee, P. Giannoni, S. Blais, G. Sommer, T. Neubert et al., In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's A?? protein, Frontiers in Aging Neuroscience, vol.12, issue.251, p.223, 2016.
DOI : 10.1038/nrn3114

S. Jang and H. Chung, Emerging Link between Alzheimer???s Disease and Homeostatic Synaptic Plasticity, Neural Plasticity, vol.12, issue.2, p.7969272, 2016.
DOI : 10.1083/jcb.201003007

URL : http://doi.org/10.1155/2016/7969272

U. Sengupta, A. Nilson, and R. Kayed, The Role of Amyloid-?? Oligomers in Toxicity, Propagation, and Immunotherapy, EBioMedicine, vol.6, pp.42-51, 2016.
DOI : 10.1016/j.ebiom.2016.03.035

Z. Amtul, M. Uhrig, L. Wang, R. Rozmahel, and K. Beyreuther, Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight, Neurobiology of Aging, vol.33, issue.4, pp.831-852, 2012.
DOI : 10.1016/j.neurobiolaging.2011.07.014

T. Hosono, A. Mouri, K. Nishitsuji, C. Jung, M. Kontani et al., Arachidonic or Docosahexaenoic Acid Diet Prevents Memory Impairment in Tg2576 Mice, Journal of Alzheimer's Disease, vol.62, issue.1, pp.149-62, 2015.
DOI : 10.1212/01.WNL.0000103860.75218.A5

T. Hosono, K. Nishitsuji, T. Nakamura, C. Jung, M. Kontani et al., Arachidonic acid diet attenuates brain A?? deposition in Tg2576 mice, Brain Research, vol.1613, pp.92-101, 2015.
DOI : 10.1016/j.brainres.2015.04.005

S. Craft, The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia, Archives of Neurology, vol.66, issue.3, pp.300-305, 2009.
DOI : 10.1001/archneurol.2009.27

S. Chung, T. Kim, C. Rico, and M. Kang, Effect of Instant Cooked Giant Embryonic Rice on Body Fat Weight and Plasma Lipid Profile in High Fat-Fed Mice, Nutrients, vol.294, issue.6, pp.2266-78, 2014.
DOI : 10.1002/ddr.20141

S. Nishikawa, A. Yasoshima, K. Doi, H. Nakayama, and K. Uetsuka, Involvement of Sex, Strain and Age Factors in High Fat Diet-Induced Obesity in C57BL/6J and BALB/cA Mice, Experimental Animals, vol.56, issue.4, pp.263-72, 2007.
DOI : 10.1538/expanim.56.263

J. Pozueta, R. Lefort, and M. Shelanski, Synaptic changes in Alzheimer???s disease and its models, Neuroscience, vol.251, pp.51-65, 2013.
DOI : 10.1016/j.neuroscience.2012.05.050

H. Hsieh, J. Boehm, C. Sato, T. Iwatsubo, T. Tomita et al., AMPAR Removal Underlies A??-Induced Synaptic Depression and Dendritic Spine Loss, Neuron, vol.52, issue.5, pp.831-874, 2006.
DOI : 10.1016/j.neuron.2006.10.035

URL : http://doi.org/10.1016/j.neuron.2006.10.035

M. Kervern, A. Angeli, O. Nicole, F. Léveillé, B. Parent et al., Selective impairment of some forms of synaptic plasticity by oligomeric amyloid-? peptide in the mouse hippocampus: implication of extrasynaptic NMDA receptors, J Alzheimers Dis, vol.32, pp.183-96, 2012.

S. Bhattacharya, W. Kimble, M. Buabeid, D. Bhattacharya, J. Bloemer et al., Altered AMPA receptor expression plays an important role in inducing bidirectional synaptic plasticity during contextual fear memory reconsolidation, Neurobiology of Learning and Memory, vol.139, pp.98-108, 2017.
DOI : 10.1016/j.nlm.2016.12.013

K. Wakabayashi, M. Narisawa-saito, Y. Iwakura, T. Arai, K. Ikeda et al., Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer???s disease???, Neurobiology of Aging, vol.20, issue.3, pp.287-95, 1999.
DOI : 10.1016/S0197-4580(99)00035-4

M. Lussier, A. Sanz-clemente, and K. Roche, -Methyl-d-aspartate (NMDA) and ??-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors by Posttranslational Modifications, Journal of Biological Chemistry, vol.20, issue.48, pp.28596-603, 2015.
DOI : 10.1038/nmeth.2519

URL : https://hal.archives-ouvertes.fr/inria-00526641

P. Cantanelli, S. Sperduti, D. Ciavardelli, L. Stuppia, V. Gatta et al., Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice, Frontiers in Aging Neuroscience, vol.87, p.200, 2014.
DOI : 10.1002/jnr.21998

G. Treccani, K. Gaarn-du-jardin, G. Wegener, and H. Müller, Differential expression of postsynaptic NMDA and AMPA receptor subunits in the hippocampus and prefrontal cortex of the flinders sensitive line rat model of depression, Synapse, vol.288, issue.11, pp.471-475, 2016.
DOI : 10.1074/jbc.M113.482000

N. Adotevi and B. Leitch, Alterations in AMPA receptor subunit expression in cortical inhibitory interneurons in the epileptic stargazer mutant mouse, Neuroscience, vol.339, pp.124-162, 2016.
DOI : 10.1016/j.neuroscience.2016.09.052

H. Rösch, R. Schweigreiter, T. Bonhoeffer, Y. Barde, and M. Korte, The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus, Proceedings of the National Academy of Sciences, vol.22, issue.6, pp.7362-7369, 2005.
DOI : 10.1016/S0014-5793(99)01628-2

Z. Amtul, D. Westaway, D. Cechetto, and R. Rozmahel, Oleic Acid Ameliorates Amyloidosis in Cellular and Mouse Models of Alzheimer's Disease, Brain Pathology, vol.27, issue.3, pp.321-330, 2011.
DOI : 10.1523/JNEUROSCI.4396-06.2007

G. Astarita, K. Jung, V. Vasilevko, N. Dipatrizio, S. Martin et al., Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease, PLoS ONE, vol.579, issue.Pt 1, p.24777, 2011.
DOI : 10.1371/journal.pone.0024777.t005

E. Oki, M. Norde, A. Carioca, R. Ikeda, J. Souza et al., Interaction of SNP in the CRP gene and plasma fatty acid profile in inflammatory pattern: A cross-sectional population-based study, Nutrition, vol.32, issue.1, pp.88-94, 2016.
DOI : 10.1016/j.nut.2015.07.015

J. Hou, B. Abraham, and H. El-serag, Dietary Intake and Risk of Developing Inflammatory Bowel Disease: A Systematic Review of the Literature, The American Journal of Gastroenterology, vol.19, issue.4, pp.563-73, 2011.
DOI : 10.1136/bmj.280.6210.293-a

O. Adam, C. Beringer, T. Kless, C. Lemmen, A. Adam et al., Anti-inflammatory effects of a low arachidonic acid diet and fish oil in patients with rheumatoid arthritis, Rheumatol Int, vol.23, pp.27-36, 2003.

G. Russo, Dietary n???6 and n???3 polyunsaturated fatty acids: From biochemistry to clinical implications in cardiovascular prevention, Biochemical Pharmacology, vol.77, issue.6, pp.937-983, 2009.
DOI : 10.1016/j.bcp.2008.10.020

J. Dwyer, H. Allayee, K. Dwyer, J. Fan, H. Wu et al., Arachidonate 5-Lipoxygenase Promoter Genotype, Dietary Arachidonic Acid, and Atherosclerosis, New England Journal of Medicine, vol.350, issue.1, pp.29-37, 2004.
DOI : 10.1056/NEJMoa025079

URL : http://doi.org/10.1016/j.jvs.2004.03.014

K. Fujimi, K. Noda, K. Sasaki, Y. Wakisaka, Y. Tanizaki et al., Altered Expression of COX-2 in Subdivisions of the Hippocampus during Aging and in Alzheimer???s Disease: The Hisayama Study, Dementia and Geriatric Cognitive Disorders, vol.23, issue.6, pp.423-454, 2007.
DOI : 10.1159/000101957

I. Mohri, K. Kadoyama, T. Kanekiyo, Y. Sato, K. Kagitani-shimono et al., Hematopoietic Prostaglandin D Synthase and DP1 Receptor Are Selectively Upregulated in Microglia and Astrocytes Within Senile Plaques From Human Patients and in a Mouse Model of Alzheimer Disease, Journal of Neuropathology and Experimental Neurology, vol.66, issue.6, pp.469-80, 2007.
DOI : 10.1097/01.jnen.0000240472.43038.27

J. Beauquis, A. Vinuesa, C. Pomilio, P. Pavía, V. Galván et al., Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease, Hippocampus, vol.8, issue.Suppl 1, pp.257-69, 2014.
DOI : 10.1371/journal.pone.0059586

P. Kamat, S. Swarnkar, S. Rai, V. Kumar, and N. Tyagi, Astrocyte mediated MMP-9 activation in the synapse dysfunction: an implication in Alzheimer disease, Ther Targets Neurol Dis, vol.1, p.243, 2014.

C. Balducci, A. Frasca, M. Zotti, L. Vitola, P. Mhillaj et al., Toll-like receptor 4-dependent glial cell activation mediates the impairment in memory establishment induced by ??-amyloid oligomers in an acute mouse model of Alzheimer???s disease, Brain, Behavior, and Immunity, vol.60, pp.188-97, 2017.
DOI : 10.1016/j.bbi.2016.10.012

C. Zhang, A. Li, S. Gao, X. Zhang, and H. Xiao, The TIP30 Protein Complex, Arachidonic Acid and Coenzyme A Are Required for Vesicle Membrane Fusion, PLoS ONE, vol.2002, issue.6, 2011.
DOI : 10.1371/journal.pone.0021233.g007

M. Goo, S. Scudder, and G. Patrick, Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors ? We accept pre-submission inquiries ? Our selector tool helps you to find the most relevant journal ? We provide round the clock customer support ? Convenient online submission ? Thorough peer review ? Inclusion in PubMed and all major indexing services ? Maximum visibility for your research Submit your manuscript at www.biomedcentral, com/submit Submit your next manuscript to BioMed Central and we will help you at every step, p.60, 2015.