Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27, Seminars in Immunology, vol.23, issue.6, pp.438-483, 2011. ,
DOI : 10.1016/j.smim.2011.08.003
A dominant function for interleukin 27 in generating interleukin 10???producing anti-inflammatory T cells, Nature Immunology, vol.25, issue.12, pp.1380-1389, 2007. ,
DOI : 10.4049/jimmunol.178.8.4779
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27???stimulated T cells, Nature Immunology, vol.7, issue.12, pp.1372-1381, 2007. ,
DOI : 10.4049/jimmunol.174.5.2814
Suppressive Effect of IL-27 on Encephalitogenic Th17 Cells and the Effector Phase of Experimental Autoimmune Encephalomyelitis, The Journal of Immunology, vol.179, issue.5, pp.3268-75, 2007. ,
DOI : 10.4049/jimmunol.179.5.3268
IL-27 Induces Th17 Differentiation in the Absence of STAT1 Signaling, The Journal of Immunology, vol.195, issue.9, pp.4144-53, 2015. ,
DOI : 10.4049/jimmunol.1302246
IL-27 mediates the response to IFN-?? therapy in multiple sclerosis patients by inhibiting Th17 cells, Brain, Behavior, and Immunity, vol.25, issue.6, pp.1170-81, 2011. ,
DOI : 10.1016/j.bbi.2011.03.007
IFN-?? Therapy Regulates TLR7-Mediated Response in Plasmacytoid Dendritic Cells of Multiple Sclerosis Patients Influencing an Anti-Inflammatory Status, Journal of Interferon & Cytokine Research, vol.35, issue.9, pp.668-81, 2015. ,
DOI : 10.1089/jir.2014.0207
IL-27: a potential biomarker for responders to glatiramer acetate therapy, Journal of Neuroimmunology, vol.304, pp.21-29, 2017. ,
DOI : 10.1016/j.jneuroim.2016.07.004
IL-27-producing CD14+ cells infiltrate inflamed joints of rheumatoid arthritis and regulate inflammation and chemotactic migration, Cytokine, vol.55, issue.2, pp.237-281, 2011. ,
DOI : 10.1016/j.cyto.2011.04.020
URL : http://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/162019/1/j.cyto.2011.04.020.pdf
IL-27 subunits and its receptor (WSX-1) mRNAs are markedly up-regulated in inflammatory cells in the CNS during experimental autoimmune encephalomyelitis, Journal of the Neurological Sciences, vol.232, issue.1-2, pp.3-9, 2005. ,
DOI : 10.1016/j.jns.2004.12.013
Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations, Brain Research, vol.1040, issue.1-2, pp.202-209, 2005. ,
DOI : 10.1016/j.brainres.2005.01.100
Production of IL-27 in multiple sclerosis lesions by astrocytes and myeloid cells: Modulation of local immune responses, Glia, vol.112, issue.4, pp.553-69, 2016. ,
DOI : 10.1016/j.clineuro.2010.04.020
Diagnostic criteria for multiple sclerosis: 2005 revisions to the ???McDonald Criteria???, Annals of Neurology, vol.6, issue.6, pp.840-846, 2005. ,
DOI : 10.1212/WNL.53.6.1184
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084507
Cerebrospinal Fluid Interleukin-6 in Central Nervous System Inflammatory Diseases, PLoS ONE, vol.31, issue.8, p.72399, 2013. ,
DOI : 10.1371/journal.pone.0072399.t002
URL : http://doi.org/10.1371/journal.pone.0072399
Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions ,
Monocyte/macrophage differentiation in early multiple sclerosis lesions, Annals of Neurology, vol.36, issue.5 ,
DOI : 10.1002/ana.410360713
Oligodendrocytes in the early course of multiple sclerosis, Annals of Neurology, vol.43, issue.1, pp.65-73, 1994. ,
DOI : 10.1007/BF00308922
Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination, Annals of Neurology, vol.143, issue.6, pp.707-724, 2000. ,
DOI : 10.1159/000111858
The Immunobiology of Interleukin-27, Annual Review of Immunology, vol.33, issue.1, pp.417-460, 2015. ,
DOI : 10.1146/annurev-immunol-032414-112134
The comparison of selected cerebrospinal fluid and serum cytokine levels in patients with multiple sclerosis and normal pressure hydrocephalus, Neuro Endocrinol Lett, vol.36, issue.6, pp.564-71, 2015. ,
The clinical significance of level changes of hs-CRP, IL-10 and TNF for patients with MS during active and relieving period, Eur Rev Med Pharmacol Sci, vol.20, issue.20, pp.4274-4280, 2016. ,
IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells, Immunity, vol.16, issue.6, pp.779-90, 2002. ,
DOI : 10.1016/S1074-7613(02)00324-2
Regulatory T Cell Suppression Is Potentiated by Target T Cells in a Cell Contact, IL-35- and IL-10-Dependent Manner, The Journal of Immunology, vol.182, issue.10, pp.6121-6129, 2009. ,
DOI : 10.4049/jimmunol.0803646
Interleukin-35: The Future of Hyperimmune-Related Diseases?, Journal of Interferon & Cytokine Research, vol.33, issue.6, pp.285-91, 2013. ,
DOI : 10.1089/jir.2012.0086
IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases, Nature, vol.42, issue.7492, pp.366-70, 2014. ,
DOI : 10.1002/eji.201142242
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260166