Iterative fecal microbiota transplantations for eradicating digestive colonization with carbapenemase-producing Enterobacteriaceae: is it worth it?

Rafael Mahieu 1 Viviane Cassisa 2 Diane Sanderink 1 Rachel Chenouard 1, 2 Hélène Pailhoriès 1, 2 Marie Kempf 1, 2 Vincent Dubée 3, 1 Matthieu Eveillard 1, 2, *
* Auteur correspondant
1 CRCINA - Département INCIT - Equipe 6 - ATIP AVENIR / ATOMycA
CRCINA - Centre de recherche de Cancérologie et d'Immunologie / Nantes - Angers
2 Laboratoire de Bactériologie [CHU Angers]
3 Service des maladies infectieuses et tropicales [CHU Angers]
Abstract : Carbapenemase-producing Enterobacteriaceae (CPE) have emerged as a major source of bacterial resistance and their dissemination is a serious public health threat.1 It has also been demonstrated that those bacteria could disseminate outside the hospital setting. A large study including 34 hospitals in Spain demonstrated that a significant proportion of patients identified as colonized or infected with CPE during hospitalization probably acquired this multi-resistant organism in a nursing home during the period preceding their hospital admission.2 In addition, a recent review of the literature demonstrated that according to US-based studies, the percentage of CPE isolates that could be associated with the community ranged from 5.6 to 10.8%.3
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Infection Control and Hospital Epidemiology, University of Chicago Press, 2017
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Soumis le : lundi 10 juillet 2017 - 15:20:24
Dernière modification le : vendredi 19 octobre 2018 - 10:02:01

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Rafael Mahieu, Viviane Cassisa, Diane Sanderink, Rachel Chenouard, Hélène Pailhoriès, et al.. Iterative fecal microbiota transplantations for eradicating digestive colonization with carbapenemase-producing Enterobacteriaceae: is it worth it?. Infection Control and Hospital Epidemiology, University of Chicago Press, 2017. 〈inserm-01559275〉

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