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Gaining Insights Into Multiple Sclerosis Lesion Characteristics from Brain Tissue Microstructure Information: A Multi-Compartment T2 Relaxometry Approach
Abstract : Clinical trends and pathogenetic ways of onset and progression of Multiple Sclerosis (MS) in patients suggest that MS is a highly heterogeneous disease. MS is predominantly a White Matter (WM) disease, which is mainly composed of myelinated axons and neuroglia type cells. Demyelination and axonal loss characterize the condition of MS in a patient. However, they follow varying trends in patients. In this work, we propose a method in which T2 relaxometry data is used to obtain a quantitative brain tissue microstructure information. This information is then studied to check its corroborations with pathogenetic understanding of MS in literature.
Cited literature [2 references]
https://www.hal.inserm.fr/inserm-01543061
Contributor : Sudhanya Chatterjee <>
Submitted on : Tuesday, June 20, 2017 - 3:52:01 PM
Last modification on : Tuesday, February 25, 2020 - 8:08:11 AM
Document(s) archivé(s) le : Sunday, December 17, 2017 - 1:07:00 PM
Contributor : Sudhanya Chatterjee <>
Submitted on : Tuesday, June 20, 2017 - 3:52:01 PM
Last modification on : Tuesday, February 25, 2020 - 8:08:11 AM
Document(s) archivé(s) le : Sunday, December 17, 2017 - 1:07:00 PM
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