Proteases: Multifunctional Enzymes in Life and Disease, Journal of Biological Chemistry, vol.283, issue.45, pp.30433-30440, 2008. ,
DOI : 10.1074/jbc.R800035200
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2576539
Human and mouse proteases: a comparative genomic approach, Nature Reviews Genetics, vol.4, issue.7, pp.544-58, 2003. ,
DOI : 10.1038/nrg1111
Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes, Protein Science, vol.152, issue.4, pp.815-851, 1998. ,
DOI : 10.1002/pro.5560070401
Serine Protease Mechanism and Specificity, Chemical Reviews, vol.102, issue.12, pp.4501-4525, 2002. ,
DOI : 10.1021/cr000033x
Membrane-Anchored Serine Proteases in Vertebrate Cell and Developmental Biology, Annual Review of Cell and Developmental Biology, vol.27, issue.1, pp.213-248, 2011. ,
DOI : 10.1146/annurev-cellbio-092910-154247
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391589
Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis, Oncogene, vol.21, issue.23, pp.3765-79, 2002. ,
DOI : 10.1038/sj.onc.1205502
Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1, The Journal of Cell Biology, vol.208, issue.4, pp.901-911, 2003. ,
DOI : 10.1046/j.1523-1747.2002.00133.x
Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway, The American Journal of Pathology, vol.175, issue.4, pp.1453-63, 2009. ,
DOI : 10.2353/ajpath.2009.090240
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751542
Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine, Proceedings of the National Academy of Sciences, vol.215, issue.2-3, pp.4200-4205, 2010. ,
DOI : 10.1007/s00232-007-9014-3
Regulation of Feto-Maternal Barrier by Matriptase- and PAR-2-Mediated Signaling Is Required for Placental Morphogenesis and Mouse Embryonic Survival, PLoS Genetics, vol.169, issue.7, p.1004470, 2014. ,
DOI : 10.1371/journal.pgen.1004470.s008
Matriptase Deletion Initiates a Sj?gren?s Syndrome-Like Disease in Mice, PLoS ONE, vol.80, issue.2, p.82852, 2014. ,
DOI : 10.1371/journal.pone.0082852.s002
URL : http://doi.org/10.1371/journal.pone.0082852
Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis, Oncogene, vol.34, issue.32, pp.3679-95, 2012. ,
DOI : 10.1159/000015125
Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation, Genes & Development, vol.19, issue.16, pp.1934-50, 2005. ,
DOI : 10.1101/gad.1300705
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1186192
Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA, Biochemical Journal, vol.149, issue.2, pp.219-247, 2010. ,
DOI : 10.1016/S0014-4827(03)00204-0
URL : https://hal.archives-ouvertes.fr/hal-00479257
Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome, Nature Genetics, vol.51, issue.8, pp.676-83, 2010. ,
DOI : 10.1074/jbc.M801970200
Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling, Nature Communications, vol.288, p.6776, 2015. ,
DOI : 10.1038/ncomms7776
Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis, Oncogene, vol.109, issue.3, pp.346-56, 2015. ,
DOI : 10.1074/jbc.M801970200
c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase, Oncogene, vol.19, issue.17, pp.2003-2019, 2011. ,
DOI : 10.1038/onc.2010.586
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084339
Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway, Proceedings of the National Academy of Sciences, vol.42, issue.4, pp.5771-5777, 2007. ,
DOI : 10.1021/bi026878f
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838401
Cellular Localization of Membrane-type Serine Protease 1 and Identification of Protease-activated Receptor-2 and Single-chain Urokinase-type Plasminogen Activator as Substrates, Journal of Biological Chemistry, vol.275, issue.34, pp.26333-26375, 2000. ,
DOI : 10.1074/jbc.M002941200
Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer, Cancer Res, vol.63, issue.5, pp.1101-1106, 2003. ,
Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis, American Journal of Respiratory and Critical Care Medicine, vol.193, issue.8, pp.847-60, 2016. ,
DOI : 10.1164/rccm.201502-0299OC
Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling, Blood, vol.127, issue.25, pp.3260-3269, 2016. ,
DOI : 10.1182/blood-2015-11-683110
A Novel Signaling Axis of Matriptase/PDGF-D/?-PDGFR in Human Prostate Cancer, Cancer Research, vol.70, issue.23, pp.9631-9671, 2010. ,
DOI : 10.1158/0008-5472.CAN-10-0511
Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis, Arthritis & Rheumatism, vol.62, issue.7, pp.1955-66, 2010. ,
DOI : 10.1002/art.27476
Molecular Cloning of cDNA for Matriptase, a Matrix-degrading Serine Protease with Trypsin-like Activity, Journal of Biological Chemistry, vol.274, issue.26, pp.18231-18237, 1999. ,
DOI : 10.1074/jbc.274.26.18231
Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains, Immunogenetics, vol.49, issue.5, pp.420-428, 1999. ,
DOI : 10.1007/s002510050515
Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin, Nature Structural & Molecular Biology, vol.22, issue.1, pp.71-77, 2006. ,
DOI : 10.1038/nsmb1035
The Activation of Matriptase Requires Its Noncatalytic Domains, Serine Protease Domain, and Its Cognate Inhibitor, Journal of Biological Chemistry, vol.278, issue.29, pp.26773-26782, 2003. ,
DOI : 10.1074/jbc.M304282200
N-terminal Processing Is Essential for Release of Epithin, a Mouse Type II Membrane Serine Protease, Journal of Biological Chemistry, vol.276, issue.48, pp.44581-44590, 2001. ,
DOI : 10.1074/jbc.M107059200
Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition, AJP: Cell Physiology, vol.297, issue.2, pp.459-70, 2009. ,
DOI : 10.1152/ajpcell.00201.2009
Transport via the Transcytotic Pathway Makes Prostasin Available as a Substrate for Matriptase, Journal of Biological Chemistry, vol.286, issue.7, pp.5793-802, 2011. ,
DOI : 10.1074/jbc.M110.186874
Reverse biochemistry: Use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue, Proceedings of the National Academy of Sciences, vol.25, issue.17, pp.11054-61, 1999. ,
DOI : 10.1021/bi00365a020
HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease, AJP: Cell Physiology, vol.289, issue.2, pp.462-70, 2005. ,
DOI : 10.1152/ajpcell.00076.2005
The optimal activity of a pseudozymogen form of recombinant matriptase under the mildly acidic pH and low ionic strength conditions, The Journal of Biochemistry, vol.147, issue.4, pp.485-92, 2010. ,
DOI : 10.1093/jb/mvp190
A Matriptase-Prostasin Reciprocal Zymogen Activation Complex with Unique Features: PROSTASIN AS A NON-ENZYMATIC CO-FACTOR FOR MATRIPTASE ACTIVATION, Journal of Biological Chemistry, vol.288, issue.26, pp.19028-19067, 2013. ,
DOI : 10.1074/jbc.M113.469932
The Protease Inhibitor HAI-2, but Not HAI-1, Regulates Matriptase Activation and Shedding through Prostasin, Journal of Biological Chemistry, vol.289, issue.32, pp.22319-22351, 2014. ,
DOI : 10.1074/jbc.M114.574400
Molecular Cloning, Tissue-specific Expression, and Cellular Localization of Human Prostasin mRNA, Journal of Biological Chemistry, vol.270, issue.22, pp.13483-13492, 1995. ,
DOI : 10.1074/jbc.270.22.13483
Protein Detection by Simple Western??? Analysis, Methods Mol Biol, vol.1312, pp.465-473, 2015. ,
DOI : 10.1007/978-1-4939-2694-7_47
Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin, Journal of Biological Chemistry, vol.291, issue.6, pp.2577-82, 2016. ,
DOI : 10.1074/jbc.C115.706721
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742728
Evidence for a Matriptase-Prostasin Proteolytic Cascade Regulating Terminal Epidermal Differentiation, Journal of Biological Chemistry, vol.281, issue.44, pp.32941-32946, 2006. ,
DOI : 10.1074/jbc.C600208200
Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin, Development, vol.143, issue.15, pp.2818-2846, 2016. ,
DOI : 10.1242/dev.137968
Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis, The American Journal of Pathology, vol.168, issue.5, pp.1513-1538, 2006. ,
DOI : 10.2353/ajpath.2006.051071
The Membrane-anchored Serine Protease Prostasin (CAP1/PRSS8) Supports Epidermal Development and Postnatal Homeostasis Independent of Its Enzymatic Activity, Journal of Biological Chemistry, vol.289, issue.21, pp.14740-14749, 2014. ,
DOI : 10.1074/jbc.M113.541318
Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo, Developmental Cell, vol.18, issue.1, pp.25-38, 2010. ,
DOI : 10.1016/j.devcel.2009.11.014
Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency?Associated Developmental Defects by Preventing Matriptase Activation, PLoS Genetics, vol.8, issue.8, p.1002937, 2012. ,
DOI : 10.1371/journal.pgen.1002937.s002
URL : http://doi.org/10.1371/journal.pgen.1002937
Autosomal Ichthyosis with Hypotrichosis Syndrome Displays Low Matriptase Proteolytic Activity and Is Phenocopied in ST14 Hypomorphic Mice, Journal of Biological Chemistry, vol.282, issue.50, pp.36714-36737, 2007. ,
DOI : 10.1074/jbc.M705521200
The mouse frizzy (fr) and rat ?hairless? (frCR) mutations are natural variants of protease serine S1 family member 8 (Prss8), Experimental Dermatology, vol.129, issue.6, pp.527-559, 2010. ,
DOI : 10.1111/j.1600-0625.2009.01054.x
Isolation, characterization, and cDNA cloning of a vampire bat salivary plasminogen activator, J Biol Chem, vol.264, issue.30, pp.17947-52, 1989. ,
Structural Features Mediating Fibrin Selectivity of Vampire Bat Plasminogen Activators, Journal of Biological Chemistry, vol.270, issue.43, pp.25596-603, 1995. ,
DOI : 10.1074/jbc.270.43.25596
Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells, AJP: Cell Physiology, vol.288, issue.4 ,
DOI : 10.1152/ajpcell.00497.2004
Tumor Detection by Imaging Proteolytic Activity, Cancer Research, vol.70, issue.4, pp.1505-1517, 2010. ,
DOI : 10.1158/0008-5472.CAN-09-1640
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823079
Detection of Active Matriptase Using a Biotinylated Chloromethyl Ketone Peptide, PLoS ONE, vol.8, issue.10, p.77146, 2013. ,
DOI : 10.1371/journal.pone.0077146.g006
Co-localization of the channel activating protease prostasin/(CAP1/PRSS8) with its candidate activator, matriptase, Journal of Cellular Physiology, vol.270, issue.1, pp.237-282, 2007. ,
DOI : 10.1002/jcp.21115
Evidence for the occurrence of membrane-type serine protease 1/matriptase on the basolateral sides of enterocytes, Biochemical Journal, vol.388, issue.2, pp.679-87, 2005. ,
DOI : 10.1042/BJ20041639
Apical serine protease activity is necessary for assembly of a high-resistance renal collecting duct epithelium, Acta Physiologica, vol.18, issue.4, pp.347-59, 2010. ,
DOI : 10.1111/j.1748-1716.2010.02170.x
Prostasin Is Required for Matriptase Activation in Intestinal Epithelial Cells to Regulate Closure of the Paracellular Pathway, Journal of Biological Chemistry, vol.288, issue.15, pp.10328-10365, 2013. ,
DOI : 10.1074/jbc.M112.443432
Matriptase Protects Against Experimental Colitis and Promotes Intestinal Barrier Recovery, Inflammatory Bowel Diseases, vol.18, issue.7, pp.1303-1317, 2012. ,
DOI : 10.1002/ibd.21930
Mutations of the Serine Protease CAP1/Prss8 Lead to Reduced Embryonic Viability, Skin Defects, and Decreased ENaC Activity, The American Journal of Pathology, vol.181, issue.2, pp.605-620, 2012. ,
DOI : 10.1016/j.ajpath.2012.05.007
ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1, EMBO Molecular Medicine, vol.163, issue.1, pp.26-37, 2009. ,
DOI : 10.1002/emmm.200900050
Colon-Specific Deletion of Epithelial Sodium Channel Causes Sodium Loss and Aldosterone Resistance, Journal of the American Society of Nephrology, vol.25, issue.7, pp.1453-64, 2014. ,
DOI : 10.1681/ASN.2013090936
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073440
Transport via the Transcytotic Pathway Makes Prostasin Available as a Substrate for Matriptase, Journal of Biological Chemistry, vol.286, issue.7, pp.5793-802, 2010. ,
DOI : 10.1074/jbc.M110.186874
Impaired wound healing in mice with a disrupted plasminogen gene, Nature Medicine, vol.10, issue.3, pp.287-92, 1996. ,
DOI : 10.1038/368419a0
The cloned thrombin receptor is necessary and sufficient for activation of mitogen-activated protein kinase and mitogenesis in mouse lung fibroblasts. Loss of responses in fibroblasts from receptor knockout mice, J Biol Chem, vol.271, issue.35, pp.21536-21577, 1996. ,