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Matriptase zymogen supports epithelial development, homeostasis and regeneration.

Résumé : Matriptase is a membrane serine protease essential for epithelial development, homeostasis, and regeneration, as well as a central orchestrator of pathogenic pericellular signaling in the context of inflammatory and proliferative diseases. Matriptase is an unusual protease in that its zymogen displays measurable enzymatic activity.
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Submitted on : Sunday, June 4, 2017 - 5:42:07 AM
Last modification on : Wednesday, August 19, 2020 - 11:17:25 AM

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Stine Friis, Daniel Tadeo, Sylvain Le-Gall, Henrik Jessen Jürgensen, Katiuchia Uzzun Sales, et al.. Matriptase zymogen supports epithelial development, homeostasis and regeneration.. BMC Biology, BioMed Central, 2017, 15 (1), pp.46. ⟨10.1186/s12915-017-0384-4⟩. ⟨inserm-01532895⟩

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