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Journal articles
Parameter Estimation in Nonlinear Mixed Effect Models Using saemix, an R Implementation of the SAEM Algorithm
Abstract : The saemix package for R provides maximum likelihood estimates of parameters in nonlinear mixed effect models, using a modern and efficient estimation algorithm, the stochastic approximation expectation-maximisation (SAEM) algorithm. In the present paper we describe the main features of the package, and apply it to several examples to illustrate its use. Making use of S4 classes and methods to provide user-friendly interaction, this package provides a new estimation tool to the R community.
Cited literature [39 references]
https://www.hal.inserm.fr/inserm-01502767
Contributor : Emmanuelle Comets <>
Submitted on : Wednesday, April 12, 2017 - 3:14:41 PM
Last modification on : Thursday, January 14, 2021 - 11:17:19 AM
Long-term archiving on: : Thursday, July 13, 2017 - 12:18:06 PM
Contributor : Emmanuelle Comets <>
Submitted on : Wednesday, April 12, 2017 - 3:14:41 PM
Last modification on : Thursday, January 14, 2021 - 11:17:19 AM
Long-term archiving on: : Thursday, July 13, 2017 - 12:18:06 PM
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