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Journal Articles International Journal of Molecular Sciences Year : 2017

PET Imaging for Initial Staging and Therapy Assessment in Multiple Myeloma Patients

Rodolphe Leforestier
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Bastien Jamet
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Cyrille Touzeau
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Philippe Moreau
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Abstract

Multiple myeloma (MM) is a hematological neoplasm characterized by the clonal proliferation of malignant plasma cells in the bone marrow. MM results in diffuse or focal bone infiltration and extramedullary lesions. Over the past two decades, advances have been made with regard to the diagnosis, staging, treatment, and imaging of MM. Computed tomography (CT) and magnetic resonance imaging (MRI) are currently recommended as the most effective imaging modalities at diagnostic. Yet, recent data from the literature suggest that positron emission tomography combined with computed tomography (PET/CT) using 18 F-deoxyglucose (FDG) is a promising technique for initial staging and therapeutic monitoring in this pathology. This paper reviews the recent advances as well as the potential place of a more specific radiopharmaceutical in MM.

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Cancer
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Dates and versions

inserm-01500327 , version 1 (03-04-2017)

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Clément Bailly, Rodolphe Leforestier, Bastien Jamet, Thomas Carlier, Mickael Bourgeois, et al.. PET Imaging for Initial Staging and Therapy Assessment in Multiple Myeloma Patients. International Journal of Molecular Sciences, 2017, 18 (2), pii: E445. ⟨10.3390/ijms18020445⟩. ⟨inserm-01500327⟩
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