R. Klein, T. Peto, A. Bird, and M. Vannewkirk, The epidemiology of age-related macular degeneration, American Journal of Ophthalmology, vol.137, issue.3, pp.486-95, 2004.
DOI : 10.1016/j.ajo.2003.11.069

J. Lee, D. Lee, J. Lee, and Y. Yoon, Correlation Between Subfoveal Choroidal Thickness and the Severity or Progression of Nonexudative Age-Related Macular Degeneration, Investigative Opthalmology & Visual Science, vol.54, issue.12, pp.7812-7820, 2013.
DOI : 10.1167/iovs.13-12284

F. Holz, D. Pauleikhoff, R. Klein, and A. Bird, Pathogenesis of lesions in late age-related macular disease, American Journal of Ophthalmology, vol.137, issue.3, pp.504-514, 2004.
DOI : 10.1016/j.ajo.2003.11.026

V. Bonilha, Age and disease-related structural changes in the retinal pigment epithelium, Clinical Ophthalmology, vol.2, issue.2, pp.413-437, 2008.
DOI : 10.2147/OPTH.S2151

B. Neuner, A. Komm, J. Wellmann, M. Dietzel, D. Pauleikhoff et al., Smoking history and the incidence of age-related macular degeneration???Results from the Muenster Aging and Retina Study (MARS) cohort and systematic review and meta-analysis of observational longitudinal studies, Addictive Behaviors, vol.34, issue.11, pp.938-985, 2009.
DOI : 10.1016/j.addbeh.2009.05.015

J. Hollyfield, Age-Related Macular Degeneration: The Molecular Link between Oxidative Damage, Tissue-Specific Inflammation and Outer Retinal Disease, Investigative Opthalmology & Visual Science, vol.51, issue.3, pp.1275-81, 2010.
DOI : 10.1167/iovs.09-4478

S. Beatty, H. Koh, M. Phil, D. Henson, M. Boulton et al., The role of oxidative stress in the pathogenesis of age-related macular degeneration Complement factor H polymorphism and age-related macular degeneration, Surv Ophthalmol. Science, vol.45308, issue.85720, pp.115-34421, 2000.

A. Dewan, M. Liu, S. Hartman, S. Zhang, D. Liu et al., HTRA1 Promoter Polymorphism in Wet Age-Related Macular Degeneration, Science, vol.314, issue.5801, pp.989-92, 2006.
DOI : 10.1126/science.1133807

H. Xu, M. Chen, and J. Forrester, Para-inflammation in the aging retina, Progress in Retinal and Eye Research, vol.28, issue.5, pp.348-68, 2009.
DOI : 10.1016/j.preteyeres.2009.06.001

E. Buschini, A. Piras, R. Nuzzi, and A. Vercelli, Age related macular degeneration and drusen: Neuroinflammation in the retina, Progress in Neurobiology, vol.95, issue.1, pp.14-25, 2011.
DOI : 10.1016/j.pneurobio.2011.05.011

F. Sennlaub, C. Auvynet, B. Calippe, S. Lavalette, L. Poupel et al., deficient mice, EMBO Molecular Medicine, vol.48, issue.11, pp.1775-93, 2013.
DOI : 10.1002/emmm.201302692
URL : https://hal.archives-ouvertes.fr/inserm-00315944

W. Raoul, C. Feumi, N. Keller, S. Lavalette, M. Houssier et al., Lipidbloated subretinal microglial cells are at the origin of drusen appearance in CX3CR1-deficient mice, Ophthalmic Res, vol.40, pp.3-4115, 2008.
URL : https://hal.archives-ouvertes.fr/inserm-00315944

N. Gupta, K. Brown, and A. Milam, Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration, Experimental Eye Research, vol.76, issue.4, pp.463-71, 2003.
DOI : 10.1016/S0014-4835(02)00332-9

S. Camelo, Potential Sources and Roles of Adaptive Immunity in Age-Related Macular Degeneration: Shall We Rename AMD into Autoimmune Macular Disease?, Autoimmune Diseases, vol.178, issue.12, pp.532487-532503, 2014.
DOI : 10.1371/journal.pone.0088201

P. Penfold, M. Killingsworth, S. Sarks, P. Penfold, M. Killingsworth et al., An ultrastructural study of the role of leucocytes and fibroblasts in the breakdown of Bruch's membrane Senile macular degeneration: the involvement of immunocompetent cells, Aust J Ophthalmol. Graefes Arch Clin Exp Ophthalmol, vol.12223, issue.172, pp.23-3169, 1984.

D. Gregerson, K. Lew, S. Mcpherson, N. Heuss, and D. Ferrington, RPE Cells Resist Bystander Killing by CTLs, but Are Highly Susceptible to Antigen-Dependent CTL Killing, Investigative Opthalmology & Visual Science, vol.47, issue.12, pp.5385-94, 2006.
DOI : 10.1167/iovs.06-0636

C. Faber, A. Singh, K. Falk, M. Juel, H. Sorensen et al., Age-related macular degeneration is associated with increased proportion of CD56(+) T cells in peripheral blood The biological functions of T helper 17 cell effector cytokines in inflammation, Ophthalmology. Immunity, vol.12028, issue.214, pp.2310-6454, 2008.

L. Steinman, A brief history of T(H)17, the first major revision in the

B. Yang, H. Kang, A. Fung, H. Zhao, T. Wang et al., The Role of Interleukin 17 in Tumour Proliferation, Angiogenesis, and Metastasis Targeting IL-17 and TH17 cells in chronic inflammation Functional specialization of interleukin-17 family members, Mediators Inflamm. Nat Rev Drug Discov. Immunity, vol.20141134, issue.252, pp.763-76149, 2011.

K. Hirota, H. Ahlfors, J. Duarte, and B. Stockinger, Regulation and function of innate and adaptive interleukin-17-producing cells, EMBO reports, vol.207, issue.2, pp.113-133, 2011.
DOI : 10.1038/embor.2011.248

L. Wei, B. Liu, J. Tuo, D. Shen, P. Chen et al., Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration, Cell Reports, vol.2, issue.5, pp.1151-1159, 2012.
DOI : 10.1016/j.celrep.2012.10.013

S. Zhang, Y. Liu, S. Lu, X. Cai, M. Franchina et al., Genetic Variants of Interleukin 17A Are Functionally Associated with Increased Risk of Age-Related Macular Degeneration, Inflammation, vol.431, issue.2
DOI : 10.1007/s10753-014-9973-3

E. Reinherz, S. Meuer, K. Fitzgerald, R. Hussey, H. Levine et al., Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex Expression Of IL-17 In Eyes Of Age-related Macular Degeneration, Cell Rep. Cell, vol.530, issue.31, pp.1527-35735, 1982.

B. Liu, L. Wei, C. Meyerle, J. Tuo, H. Sen et al., Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in age-related macular degeneration Molecular pathology of macrophages and interleukin-17 in agerelated macular degeneration, J Transl Med. Adv Exp Med Biol, vol.9801, issue.34, pp.1-12193, 2011.

Y. Chen, P. Yang, F. Li, and A. Kijlstra, The Effects of Th17 Cytokines on the Inflammatory Mediator Production and Barrier Function of ARPE-19 Cells, PLoS ONE, vol.107, issue.3, pp.18139-18175, 2011.
DOI : 10.1371/journal.pone.0018139.g005

Z. Zhao, P. Xu, Z. Jie, Y. Zuo, Y. B. Soong et al., gammadelta T cells as a major source of IL-17 production during age-dependent RPE degeneration, Invest Ophthalmol Vis Sci, 2014.