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Sleep disorders in neurology French consensus. Idiopathic hypersomnia: Investigations and follow-up

Abstract : Idiopathic hypersomnia is a rare, central hypersomnia, recently identified and to date of unknown physiopathology. It is characterised by a more or less permanent, excessive daytime sleepiness, associated with long and unrefreshing naps. Night-time sleep is of good quality, excessive in quantity, associated with sleep inertia in the subtype previously described as "with long sleep time". Diagnosis of idiopathic hypersomnia is complex due to the absence of a quantifiable biomarker, the heterogeneous symptoms, which overlap with the clinical picture of type 2 narcolepsy, and its variable evolution over time. Detailed evaluation enables other frequent causes of somnolence, such as depression or sleep deprivation, to be eliminated. Polysomnography and multiple sleep latency tests (MSLT) are essential to rule out other sleep pathologies and to objectify excessive daytime sleepiness. Sometimes the MSLT do not show excessive sleepiness, hence a continued sleep recording of at least 24hours is necessary to show prolonged sleep (>11h/24h). In this article, we propose recommendations for the work-up to be carried out during diagnosis and follow-up for patients suffering from idiopathic hypersomnia.
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https://www.hal.inserm.fr/inserm-01484944
Contributor : Yves Dauvilliers <>
Submitted on : Wednesday, March 8, 2017 - 9:20:51 AM
Last modification on : Thursday, August 20, 2020 - 3:20:23 AM
Long-term archiving on: : Friday, June 9, 2017 - 12:52:42 PM

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Smaranda Leu-Semenescu, Maria Antonia Quera-Salva, Yves Dauvilliers. Sleep disorders in neurology French consensus. Idiopathic hypersomnia: Investigations and follow-up. Revue Neurologique, Elsevier Masson, 2017, 173 (1-2), pp.32-37. ⟨10.1016/j.neurol.2016.09.015⟩. ⟨inserm-01484944⟩

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