J. Anderson, B. Johnstone, and D. Remley, Breast-feeding and cognitive development: a meta-analysis, Am J Clin Nutr, vol.70, pp.525-560, 1999.

J. Bernard, D. Agostini, M. Forhan, A. Alfaiate, T. Bonet et al., Breastfeeding Duration and Cognitive Development at 2 and 3 Years of Age in the EDEN Mother???Child Cohort, The Journal of Pediatrics, vol.163, issue.1, pp.36-42, 2013.
DOI : 10.1016/j.jpeds.2012.11.090
URL : https://hal.archives-ouvertes.fr/inserm-00788598

M. Quigley, C. Hockley, C. Carson, Y. Kelly, M. Renfrew et al., Breastfeeding is Associated with Improved Child Cognitive Development: A Population-Based Cohort Study, The Journal of Pediatrics, vol.160, issue.1, pp.25-32, 2012.
DOI : 10.1016/j.jpeds.2011.06.035

M. Belfort, S. Rifas-shiman, K. Kleinman, L. Guthrie, D. Bellinger et al., Infant Feeding and Childhood Cognition at Ages 3 and 7 Years, JAMA Pediatrics, vol.167, issue.9, pp.836-880, 2013.
DOI : 10.1001/jamapediatrics.2013.455
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998659

C. Victora, B. Horta, C. De-mola, L. Quevedo, R. Pinheiro et al., Association between breastfeeding and intelligence, educational attainment, and income at 30 years of age: a prospective birth cohort study from Brazil, The Lancet Global Health, vol.3, issue.4, pp.199-205, 2015.
DOI : 10.1016/S2214-109X(15)70002-1

S. Jacobson, L. Chiodo, and J. Jacobson, Breastfeeding Effects on Intelligence Quotient in 4-??and 11-Year-Old Children, PEDIATRICS, vol.103, issue.5, p.71, 1999.
DOI : 10.1542/peds.103.5.e71

G. Der, G. Batty, and I. Deary, Effect of breast feeding on intelligence in children: prospective study, sibling pairs analysis, and meta-analysis, BMJ, vol.333, issue.7575, p.945, 2006.
DOI : 10.1136/bmj.38978.699583.55

N. Andreas, B. Kampmann, M. Le-doare, and K. , Human breast milk: A review on its composition and bioactivity, Early Human Development, vol.91, issue.11, pp.629-664, 2015.
DOI : 10.1016/j.earlhumdev.2015.08.013

B. Koletzko, L. E. Agostoni, C. Bohles, H. Campoy, C. Cetin et al., The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations, Journal of Perinatal Medicine, vol.36, issue.1, pp.5-14, 2008.
DOI : 10.1515/JPM.2008.001

K. Simmer, S. Patole, and S. Rao, Long-chain polyunsaturated fatty acid supplementation in infants born at term, Cochrane Database Syst Rev, vol.4, p.376, 2011.

J. Jacobson, S. Jacobson, G. Muckle, M. Kaplan-estrin, P. Ayotte et al., Beneficial Effects of a Polyunsaturated Fatty Acid on Infant Development: Evidence from the Inuit of Arctic Quebec, The Journal of Pediatrics, vol.152, issue.3, pp.356-64, 2008.
DOI : 10.1016/j.jpeds.2007.07.008

M. Guxens, M. Mendez, C. Molto-puigmarti, J. Julvez, R. Garcia-esteban et al., Breastfeeding, Long-Chain Polyunsaturated Fatty Acids in Colostrum, and Infant Mental Development, PEDIATRICS, vol.128, issue.4, pp.880-889, 2011.
DOI : 10.1542/peds.2010-1633

J. Julvez, M. Guxens, A. Carsin, J. Forns, M. Mendez et al., A cohort study on full breastfeeding and child neuropsychological development: the role of maternal social, psychological, and nutritional factors, Developmental Medicine & Child Neurology, vol.16, issue.2
DOI : 10.1111/dmcn.12282

J. Bernard, A. M. Garcia, C. Forhan, A. , D. Agostini et al., The association between linoleic acid levels in colostrum and child cognition at 2 and 3 y in the EDEN cohort, Pediatric Research, vol.85, issue.6, pp.829-864, 2015.
DOI : 10.1194/jlr.D500022-JLR200
URL : https://hal.archives-ouvertes.fr/hal-01414358

B. Heude, A. Forhan, R. Slama, L. Douhaud, S. Bedel et al., Cohort Profile: The EDEN mother-child cohort on the prenatal and early postnatal determinants of child health and development, International Journal of Epidemiology, vol.45, issue.2, pp.353-63, 2016.
DOI : 10.1093/ije/dyv151

R. Fuhrer and F. Rouillon, La version française de l'échelle CES-D (Center for Epidemiologic Studies-Depression Scale) Description et traduction de l'échelle d'autoévaluation. / The French version of the CES-D (Center for Epidemiologic Studies-Depression Scale), Eur Psychiatr, vol.4, pp.163-169, 1989.

N. Mamelle, F. Munoz, and H. Grandjean, Fetal growth from the AUDIPOG study. I. Establishment of reference curves], J Gynecol Obstet Biol Reprod (Paris), vol.25, pp.61-70, 1995.

B. Caldwell and R. Bradley, Home Observation for Measurement of the Environment, 1984.

M. Bonet, L. Marchand, M. Kaminski, A. Fohran, A. Betoko et al., Breastfeeding Duration, Social and Occupational Characteristics of Mothers in the French ???EDEN Mother???Child??? Cohort, Maternal and Child Health Journal, vol.122, issue.Suppl 2, pp.714-736, 2013.
DOI : 10.1007/s10995-012-1053-4
URL : https://hal.archives-ouvertes.fr/inserm-00912770

A. Masood, K. Stark, N. Salem, and . Jr, A simplified and efficient method for the analysis of fatty acid methyl esters suitable for large clinical studies, The Journal of Lipid Research, vol.46, issue.10
DOI : 10.1194/jlr.D500022-JLR200

D. Wechsler, Wechsler Preschool and Primary Scale of Intelligence (WPPSI- III) San Antonio (TX): Psychological Corporation, 2002.

M. Kramer, F. Aboud, E. Mironova, I. Vanilovich, R. Platt et al., Breastfeeding and Child Cognitive Development, Archives of General Psychiatry, vol.65, issue.5, pp.578-84, 2008.
DOI : 10.1001/archpsyc.65.5.578

J. Dunstan, L. Mitoulas, G. Dixon, D. Doherty, P. Hartmann et al., The Effects of Fish Oil Supplementation in Pregnancy on Breast Milk Fatty Acid Composition Over the Course of Lactation: A Randomized Controlled Trial, Pediatric Research, vol.143, issue.6, pp.689-94, 2007.
DOI : 10.1203/PDR.0b013e318159a93a

C. Molto-puigmarti, A. Castellote, X. Carbonell-estrany, and M. Lopez-sabater, Differences in fat content and fatty acid proportions among colostrum, transitional, and mature milk from women delivering very preterm, preterm,??and??term infants, Clinical Nutrition, vol.30, issue.1, pp.116-139, 2011.
DOI : 10.1016/j.clnu.2010.07.013

M. Brion, D. Lawlor, A. Matijasevich, B. Horta, L. Anselmi et al., What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts, International Journal of Epidemiology, vol.40, issue.3, pp.670-80, 2011.
DOI : 10.1093/ije/dyr020

K. Clark, M. Castillo, A. Calatroni, T. Walter, M. Cayazzo et al., Breast-feeding and Mental and Motor Development at 5?? Years, Ambulatory Pediatrics, vol.6, issue.2, pp.65-71, 2006.
DOI : 10.1016/j.ambp.2005.11.003
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540451

M. Kramer, E. Fombonne, S. Igumnov, I. Vanilovich, L. Matush et al., Effects of Prolonged and Exclusive Breastfeeding on Child Behavior and Maternal Adjustment: Evidence From a Large, Randomized Trial, PEDIATRICS, vol.121, issue.3, pp.435-475, 2008.
DOI : 10.1542/peds.2007-1248

H. Peyre, J. Bernard, N. Hoertel, A. Forhan, M. Charles et al., Differential effects of factors influencing cognitive development at the age of 5-to-6 years, Cognitive Development, vol.40, pp.152-62, 2016.
DOI : 10.1016/j.cogdev.2016.10.001

K. Sabel, B. Strandvik, M. Petzold, and C. Lundqvist-persson, Motor, mental and behavioral developments in infancy are associated with fatty acid pattern in breast milk and plasma of premature infants, Prostaglandins, Leukotrienes and Essential Fatty Acids, vol.86, issue.4-5, pp.183-191, 2012.
DOI : 10.1016/j.plefa.2012.02.008

W. Lassek and S. Gaulin, Linoleic and docosahexaenoic acids in human milk have opposite relationships with cognitive test performance in a sample of 28 countries, Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), vol.91, issue.5, pp.195-201, 2014.
DOI : 10.1016/j.plefa.2014.07.017

W. Heird and A. Lapillonne, THE ROLE OF ESSENTIAL FATTY ACIDS IN DEVELOPMENT, Annual Review of Nutrition, vol.25, issue.1, pp.549-71, 2005.
DOI : 10.1146/annurev.nutr.24.012003.132254

J. Brenna, Arachidonic acid needed in infant formula when docosahexaenoic acid is present, Nutrition Reviews, vol.74, issue.5, pp.329-365, 2016.
DOI : 10.1093/nutrit/nuw007

C. Janssen and A. Kiliaan, Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: The influence of LCPUFA on neural development, aging, and neurodegeneration, Progress in Lipid Research, vol.53, pp.1-17, 2014.
DOI : 10.1016/j.plipres.2013.10.002

C. Blank, M. Neumann, M. Makrides, and R. Gibson, Optimizing DHA levels in piglets by lowering the linoleic acid to alpha-linolenic acid ratio, The Journal of Lipid Research, vol.43, issue.9, pp.1537-1580, 2002.
DOI : 10.1194/jlr.M200152-JLR200

E. Novak, R. Dyer, and S. Innis, High dietary ??-6 fatty acids contribute to reduced docosahexaenoic acid in the developing brain and inhibit secondary neurite growth, Brain Research, vol.1237, pp.136-181, 2008.
DOI : 10.1016/j.brainres.2008.07.107

J. Gould, L. Smithers, and M. Makrides, The effect of maternal omega-3 (n-3) LCPUFA supplementation during pregnancy on early childhood cognitive and visual development: a systematic review and meta-analysis of randomized controlled trials, American Journal of Clinical Nutrition, vol.97, issue.3, pp.531-575, 2013.
DOI : 10.3945/ajcn.112.045781

J. Bernard, A. M. Forhan, A. , D. Agostini, M. Charles et al., Early life exposure to polyunsaturated fatty acids and psychomotor development in children from the EDEN mother-child cohort, OCL, vol.23, issue.1, p.106, 2016.
DOI : 10.1051/ocl/2015060
URL : https://hal.archives-ouvertes.fr/hal-01425514

S. Innis, Impact of maternal diet on human milk composition and neurological development of infants, American Journal of Clinical Nutrition, vol.99, issue.3, pp.734-775, 2014.
DOI : 10.3945/ajcn.113.072595

F. Tosi, F. Sartori, P. Guarini, O. Olivieri, and N. Martinelli, Delta-5 and Delta-6 Desaturases: Crucial Enzymes in Polyunsaturated Fatty Acid-Related Pathways with Pleiotropic Influences in Health and Disease, Adv Exp Med Biol, vol.824, pp.61-81, 2014.
DOI : 10.1007/978-3-319-07320-0_7

E. Lattka, P. Rzehak, E. Szabo, V. Jakobik, M. Weck et al., Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9-octadecenoic acid concentrations over the duration of lactation, American Journal of Clinical Nutrition, vol.93, issue.2, pp.382-91, 2011.
DOI : 10.3945/ajcn.110.004515

A. Caspi, B. Williams, J. Kim-cohen, I. Craig, B. Milne et al., Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism, Proceedings of the National Academy of Sciences, vol.104, issue.47, pp.18860-18865, 2007.
DOI : 10.1073/pnas.0704292104

C. Steer, D. Smith, G. Emmett, P. Hibbeln, J. Golding et al., FADS2 Polymorphisms Modify the Effect of Breastfeeding on Child IQ, PLoS ONE, vol.62, issue.7, p.11570, 2010.
DOI : 10.1371/journal.pone.0011570.s006

C. Steer, E. Lattka, B. Koletzko, J. Golding, and J. Hibbeln, Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age, American Journal of Clinical Nutrition, vol.98, issue.6, pp.1575-82, 2013.
DOI : 10.3945/ajcn.112.051524

C. Garcia, R. Duan, V. Brevaut-malaty, C. Gire, V. Millet et al., Bioactive compounds in human milk and intestinal health and maturity in preterm newborn: an overview, Cell Mol Biol (Noisy-Le-Grand), vol.59, pp.108-139, 2013.
URL : https://hal.archives-ouvertes.fr/inserm-01098435

T. Journal, jpeds.com Volume ?? Additional members of the EDEN Mother-Child Cohort Study Group include: Isabella Annesi-Maesano, PhD (Inserm

N. Lelong, . Msc, . Inserm, F. ). Paris, J. Lepeuleinserm et al., Cathy Nabet Rémy Slama, PhD (Inserm, Michel Schweitzer) ?0.4 (?0.9, 0.2) ?0.6 (?1.1, pp.2-6

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