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ARF1 at the crossroads of podosome construction and function

Abstract : Podosomes are actin-based proteolytic microdomains of the plasma membrane found in cells that travel across tissues. In this issue, Rafiq et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605104) reveal that the small guanosine triphosphatase ARF1, a well-known orchestrator of membrane traffic at the Golgi, regulates podosome formation, maintenance, and function.
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Contributor : Elisabeth Genot <>
Submitted on : Tuesday, January 10, 2017 - 12:58:05 PM
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Elisabeth Genot. ARF1 at the crossroads of podosome construction and function. Journal of Cell Biology, Rockefeller University Press, 2017, 216 (1), pp.13-15. ⟨10.1083/jcb.201611097⟩. ⟨inserm-01430857⟩

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