S. Cruz-biotechnology, S. Cruz, and C. , mouse anti-core 19D9D6 (kind gift from C), rat anti-E2 clone 3/11 (kind gift from, mouse anti-NS5A 9E10 (kind gift from C. Rice rabbit anti- NS4B (kind gift from M. Kohara, Tokyo Metropolitan Institute of Medical Science, p.790052

S. Chemicals and . Houston, A922500 (Sigma-Aldrich), CHX (Sigma-Aldrich), Mowiol 40-88 (Fluka), Bodipy 493/503 and Hoecsht 33342 (Molecular Probes Europe BV) Protease/phosphatase inhibitor cocktail) was used according to manufacturer's instructions